Literature DB >> 26029648

Top five medical innovations in China mainland since Xinhai revolution [1911]: results of AME survey-002.

Yì-Xiáng J Wáng1, Fan Xiao1.   

Abstract

OBJECTIVE: This survey aims to scrutinize important medical innovations in Chinese mainland since Xinhai (Hsin-hai) revolution in 1911, which marked the end of Manchurian imperial rule and the beginning of China's republican era.
METHODS: An online cross-sectional survey was carried out during the period of Dec 29, 2014 to Feb 5, 2015, totaling 37 days. The survey was conducted on the platform provided by DXY (www.dxy.cn), which is the largest medical and paramedical related website in China. An email was sent to all DXY registered users to invite them to participate in a 5-minute survey. The participants were asked to nominate up to four important medical innovations in China mainland since Xinhai revolution. The participant could select 'zero' which means he/she felt there was no important medical innovations, or he/she did not know important medical innovations. It was noted that important medical innovations refer to (I) those with practical and almost immediate significance to improve healthcare; (II) should not only be introducing western technique to China, but those involve major improvement of existing western techniques count; (III) should not be those with important theoretical discovery but did not have almost immediate significance to improve healthcare.
RESULTS: In total 1,513 DXY users participated in the voting. Totally 489 (32.3%), 441 (29.1%), 342 (22.6%), 150 (9.9%), 91 (6.0%) participants provided 0, 1, 2, 3, 4 nominations respectively. (I) Artemisine (Qinghaosu) for malaria treatment (Project 523 team, 1972); (II) arsenic Trioxide (As2O3) for acute promyelocytic leukemia (APL) treatment (ZHANG Ting-Dong and colleagues, 1970s); (III) limb re-plantation (CHEN Zhong-Wei and colleagues, 1963); (IV) all-trans retinoic acid (ATRA) for APL treatment (WANG Zhen-Yi and colleagues, 1988); and (V) Wu's mask for plague prevention (WU Lien-The, 1910), were voted as the top five innovations in China mainland since Xinhai revolution, with 375, 96, 91, 53, and 8 votes respectively.
CONCLUSIONS: In this voting exercise, five achievements were voted as top innovations in China mainland since Xinhai revolution. However, only ATRA for APL treatment was accomplished after the ending of Great Proletarian Cultural Revolution in year 1976 in China.

Entities:  

Keywords:  Technology innovation; dialectics of nature; history of science; history of technology; inventions and discoveries

Year:  2015        PMID: 26029648      PMCID: PMC4426111          DOI: 10.3978/j.issn.2223-4292.2015.03.10

Source DB:  PubMed          Journal:  Quant Imaging Med Surg        ISSN: 2223-4306


  69 in total

1.  A biography of arsenic and medicine in Hong Kong and China.

Authors:  W Y Au
Journal:  Hong Kong Med J       Date:  2011-12       Impact factor: 2.227

2.  The mode of virus multiplication and the susceptibility of these agents to the antibiotics.

Authors:  S P BEDSON
Journal:  J Clin Pathol       Date:  1956-05       Impact factor: 3.411

3.  The amino-acid sequence in the phenylalanyl chain of insulin. I. The identification of lower peptides from partial hydrolysates.

Authors:  F SANGER; H TUPPY
Journal:  Biochem J       Date:  1951-09       Impact factor: 3.857

4.  Acupuncture in patients with osteoarthritis of the knee: a randomised trial.

Authors:  C Witt; B Brinkhaus; S Jena; K Linde; A Streng; S Wagenpfeil; J Hummelsberger; H U Walther; D Melchart; S N Willich
Journal:  Lancet       Date:  2005 Jul 9-15       Impact factor: 79.321

5.  Replantation of severed fingers. Clinical experiences in 217 cases involving 373 severed fingers.

Authors: 
Journal:  Chin Med J (Engl)       Date:  1975-05       Impact factor: 2.628

6.  Total synthesis of crystalline bovine insulin.

Authors:  Y T Kung; Y C Du; W T Huang; C C Chen; L T Ke
Journal:  Sci Sin       Date:  1965-11

7.  Arsenic trioxide in comparison with chemotherapy and bone marrow transplantation for the treatment of relapsed acute promyelocytic leukaemia.

Authors:  W Y Au; A K W Lie; C S Chim; R Liang; S K Ma; C H Chan; Y K Mak; Y T Chen; C C So; Y M Yeung; S F Yip; L G Wong; J C Chan; S Y Liu; Y L Kwong
Journal:  Ann Oncol       Date:  2003-05       Impact factor: 32.976

8.  A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic leukemia patients.

Authors:  Z X Chen; Y Q Xue; R Zhang; R F Tao; X M Xia; C Li; W Wang; W Y Zu; X Z Yao; B J Ling
Journal:  Blood       Date:  1991-09-15       Impact factor: 22.113

Review 9.  Qinghaosu (artemisinin): an antimalarial drug from China.

Authors:  D L Klayman
Journal:  Science       Date:  1985-05-31       Impact factor: 47.728

Review 10.  Acupuncture for chronic pain: individual patient data meta-analysis.

Authors:  Andrew J Vickers; Angel M Cronin; Alexandra C Maschino; George Lewith; Hugh MacPherson; Nadine E Foster; Karen J Sherman; Claudia M Witt; Klaus Linde
Journal:  Arch Intern Med       Date:  2012-10-22
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2.  The role of Chaoyang People's Hospital for the development of trioxide as an effective treatment for acute promyelocytic leukemia treatment.

Authors:  Yì-Xiáng J Wáng
Journal:  Quant Imaging Med Surg       Date:  2015-10

3.  AME survey-003 A1-part1: in current China, do you regret you joined the medical profession.

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4.  Why China is currently underperforming in medical innovation and what China can do about it?-Part I.

Authors:  Yì-Xiáng J Wáng; Fan Xiao
Journal:  Quant Imaging Med Surg       Date:  2015-06

5.  Why China is currently underperforming in medical innovation and what China can do about it?-Part II.

Authors:  Yì-Xiáng J Wáng
Journal:  Quant Imaging Med Surg       Date:  2015-06

6.  Successfully Replanted An Amputated Hand: A Case Report.

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  6 in total

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