Literature DB >> 26028466

The relationship between telomere length and beekeeping among Malaysians.

Nurul Fatihah Mohamad Nasir1, Thirumulu Ponnuraj Kannan, Siti Amrah Sulaiman, Shaharum Shamsuddin, Ahmad Azlina, Stefan Stangaciu.   

Abstract

The belief that beekeepers live longer than anyone else is present since ages. However, no research has been done to explore the longevity of life in beekeepers. Here, we investigated the telomere length in 30 male beekeepers and 30 male non-beekeepers and associated them with the longevity of life using Southern analysis of terminal restriction fragments (TRFs) generated by Hinf I/Rsa I digestion of human genomic DNA using TeloTAGGG Telomere Length Assay. Interestingly, we found that the telomere length of male beekeepers was significantly longer than those of male non-beekeepers with a p value of less than 0.05, suggesting that beekeepers may have longer life compared to non-beekeepers. We further found that the consumption of bee products for a long period and frequent consumption of bee products per day are associated with telomere length. An increase of year in consuming bee products is associated with a mean increase in telomere length of 0.258 kbp. In addition, an increase in frequency of eating bee products per day was also associated with a mean increase of 2.66 kbp in telomere length. These results suggested that bee products might play some roles in telomere length maintenance.

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Year:  2015        PMID: 26028466      PMCID: PMC4450150          DOI: 10.1007/s11357-015-9797-6

Source DB:  PubMed          Journal:  Age (Dordr)        ISSN: 0161-9152


  35 in total

1.  Site-specific DNA damage at the GGG sequence by UVA involves acceleration of telomere shortening.

Authors:  S Oikawa; S Tada-Oikawa; S Kawanishi
Journal:  Biochemistry       Date:  2001-04-17       Impact factor: 3.162

Review 2.  Structure and function of telomeres.

Authors:  E H Blackburn
Journal:  Nature       Date:  1991-04-18       Impact factor: 49.962

Review 3.  A natural history of human tree climbing.

Authors:  Thomas S Kraft; Vivek V Venkataraman; Nathaniel J Dominy
Journal:  J Hum Evol       Date:  2014-03-12       Impact factor: 3.895

4.  [Principle of marginotomy in template synthesis of polynucleotides].

Authors:  A M Olovnikov
Journal:  Dokl Akad Nauk SSSR       Date:  1971

5.  Antioxidant and radical scavenging activity of honey in endothelial cell cultures (EA.hy926).

Authors:  Giangiacomo Beretta; Marica Orioli; Roberto Maffei Facino
Journal:  Planta Med       Date:  2007-09-07       Impact factor: 3.352

6.  Mechanism of telomere shortening by oxidative stress.

Authors:  Shosuke Kawanishi; Shinji Oikawa
Journal:  Ann N Y Acad Sci       Date:  2004-06       Impact factor: 5.691

7.  Telomeres shorten during ageing of human fibroblasts.

Authors:  C B Harley; A B Futcher; C W Greider
Journal:  Nature       Date:  1990-05-31       Impact factor: 49.962

8.  Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization.

Authors:  C M Counter; W C Hahn; W Wei; S D Caddle; R L Beijersbergen; P M Lansdorp; J M Sedivy; R A Weinberg
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

9.  DNA polymerase beta interacts with TRF2 and induces telomere dysfunction in a murine mammary cell line.

Authors:  Poppy Fotiadou; Octavian Henegariu; Joann B Sweasy
Journal:  Cancer Res       Date:  2004-06-01       Impact factor: 12.701

10.  Slow-down of age-dependent telomere shortening is executed in human skin keratinocytes by hormesis-like-effects of trace hydrogen peroxide or by anti-oxidative effects of pro-vitamin C in common concurrently with reduction of intracellular oxidative stress.

Authors:  Seiichi Yokoo; Kayo Furumoto; Eiso Hiyama; Nobuhiko Miwa
Journal:  J Cell Biochem       Date:  2004-10-15       Impact factor: 4.429

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  1 in total

1.  Recent advances of Blood telomere length (BTL) shortening: A potential biomarker for development of cancer.

Authors:  Paramita Mandal
Journal:  Pathol Oncol Res       Date:  2018-06-08       Impact factor: 3.201

  1 in total

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