Literature DB >> 1708110

Structure and function of telomeres.

E H Blackburn.   

Abstract

The DNA of telomeres--the terminal DNA-protein complexes of chromosomes--differs notably from other DNA sequences in both structure and function. Recent work has highlighted its remarkable mode of synthesis by the ribonucleoprotein reverse transcriptase, telomerase, as well as its ability to form unusual structures in vitro. Moreover, telomere synthesis by telomerase has been shown to be essential for telomere maintenance and long-term viability.

Mesh：

Substances：

Year:  1991        PMID： 1708110     DOI： 10.1038/350569a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  883 in total

1.  TIN2, a new regulator of telomere length in human cells.

Authors:  S H Kim; P Kaminker; J Campisi
Journal:  Nat Genet       Date:  1999-12       Impact factor: 38.330

2.  Double hybridization signals on the chromatid revealed by telomeric probes.

Authors:  C Philippe; P Coullin; A Bernheim
Journal:  Chromosome Res       Date:  1999       Impact factor: 5.239

3.  The length of telomeric G-rich strand 3'-overhang measured by oligonucleotide ligation assay.

Authors:  G Cimino-Reale; E Pascale; E Battiloro; G Starace; R Verna; E D'Ambrosio
Journal:  Nucleic Acids Res       Date:  2001-04-01       Impact factor: 16.971

4.  The effect of sodium, potassium and ammonium ions on the conformation of the dimeric quadruplex formed by the Oxytricha nova telomere repeat oligonucleotide d(G(4)T(4)G(4)).

Authors:  P Schultze; N V Hud; F W Smith; J Feigon
Journal:  Nucleic Acids Res       Date:  1999-08-01       Impact factor: 16.971

5.  The coevolution of cell senescence and diploid sexual reproduction in unicellular organisms.

Authors:  Y Cui; R S Chen; W H Wong
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-28       Impact factor: 11.205

6.  Establishment of novel human esophageal cancer cell line in relation to telomere dynamics and telomerase activity.

Authors:  Y Kiyozuka; A Asai; D Yamamoto; H Senzaki; S Yoshioka; H Takahashi; K Hioki; A Tsubura
Journal:  Dig Dis Sci       Date:  2000-05       Impact factor: 3.199

7.  Three telomerases with completely non-telomeric template replacements are catalytically active.

Authors:  T L Ware; H Wang; E H Blackburn
Journal:  EMBO J       Date:  2000-06-15       Impact factor: 11.598

8.  Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA.

Authors:  H Niida; Y Shinkai; M P Hande; T Matsumoto; S Takehara; M Tachibana; M Oshimura; P M Lansdorp; Y Furuichi
Journal:  Mol Cell Biol       Date:  2000-06       Impact factor: 4.272

9.  An anchorage nuclear structure for telomeric DNA repeats in HeLa cells.

Authors:  G Pierron; F Puvion-Dutilleul
Journal:  Chromosome Res       Date:  1999       Impact factor: 5.239

10.  The function of DNA polymerase alpha at telomeric G tails is important for telomere homeostasis.

Authors:  A Adams Martin; I Dionne; R J Wellinger; C Holm
Journal:  Mol Cell Biol       Date:  2000-02       Impact factor: 4.272
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.