Literature DB >> 26025972

Systemic aspergilloma post aortic root surgery following coronary artery stenting: diagnostic and management dilemma.

Nabil Hussein1, Sombul Qamar2, Qamar Abid3.   

Abstract

Aspergillus infections such as Aspergillus endocarditis were once relatively rare occurrences, however, due to the increased use of intracardiac devices, the incidence has grown. With mortality rates close to 100%, in medically treated cases, it is paramount that early diagnosis and treatment are performed. An immunocompetent aviculturist presented 8 months post aortic root replacement for severe aortic regurgitation with a composite graft, with central crushing chest pain. Investigations confirmed ST elevation inferior myocardial infarction due to stenosis of the origin of the right coronary artery, which was stented. Echocardiogram demonstrated a mobile mass posterior to the left ventricular outflow tract. Following referral to our cardiothoracic surgeons, a polypoidal mass covering the right ostial button was noted along with systemic complications of the disease. Emergency redo aortic valve replacement with a homograft and coronary artery bypass was performed. Histological analysis confirmed A. fumigatus and the patient was started on intravenous voriconazole. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26025972      PMCID: PMC4458591          DOI: 10.1136/bcr-2014-207702

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  13 in total

Review 1.  Aspergillus endocarditis: a review of the literature.

Authors:  Ameeta S Kalokhe; Nadine Rouphael; Mikhael F El Chami; Kimberly A Workowski; Geeta Ganesh; Jesse T Jacob
Journal:  Int J Infect Dis       Date:  2010-10-29       Impact factor: 3.623

Review 2.  Aspergillus endocarditis after cardiac surgery.

Authors:  Ismaïl El-Hamamsy; Nicolas Dürrleman; Louis-Mathieu Stevens; Louis P Perrault; Michel Carrier
Journal:  Ann Thorac Surg       Date:  2005-07       Impact factor: 4.330

3.  Voriconazole-induced photosensitivity.

Authors:  Anurag N Malani; David M Aronoff
Journal:  Clin Med Res       Date:  2008-09-18

4.  Interaction between Aspergillus fumigatus and basement membrane laminin: binding and substrate degradation.

Authors:  G Tronchin; J P Bouchara; G Larcher; J C Lissitzky; D Chabasse
Journal:  Biol Cell       Date:  1993       Impact factor: 4.458

5.  Impact of air filtration on nosocomial Aspergillus infections. Unique risk of bone marrow transplant recipients.

Authors:  R J Sherertz; A Belani; B S Kramer; G J Elfenbein; R S Weiner; M L Sullivan; R G Thomas; G P Samsa
Journal:  Am J Med       Date:  1987-10       Impact factor: 4.965

6.  Molecular diagnosis of Aspergillus endocarditis after cardiac surgery.

Authors:  Parisa Badiee; Abdolvahab Alborzi; Elaheh Shakiba; Mazyar Ziyaeyan; Bahman Pourabbas
Journal:  J Med Microbiol       Date:  2009-02       Impact factor: 2.472

7.  Identification of an agent in cultures of Aspergillus fumigatus displaying anti-phagocytic and immunomodulating activity in vitro.

Authors:  A Müllbacher; P Waring; R D Eichner
Journal:  J Gen Microbiol       Date:  1985-05

8.  Embolic aspergillus endophthalmitis in an immunocompetent patient from aortic root aspergillus endocarditis.

Authors:  Mrinal Rana; Badia Fahad; Qamar Abid
Journal:  Mycoses       Date:  2008-03-04       Impact factor: 4.377

Review 9.  Fungal endocarditis, 1995-2000.

Authors:  Lígia C Pierrotti; Larry M Baddour
Journal:  Chest       Date:  2002-07       Impact factor: 9.410

10.  Surgical and long-term antifungal therapy for fungal prosthetic valve endocarditis.

Authors:  D D Muehrcke; B W Lytle; D M Cosgrove
Journal:  Ann Thorac Surg       Date:  1995-09       Impact factor: 4.330

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