Uyên Châu Nguyên1, Mark Potse2, François Regoli3, Maria Luce Caputo3, Giulio Conte3, Romina Murzilli3, Stefano Muzzarelli3, Tiziano Moccetti3, Enrico G Caiani4, Frits W Prinzen5, Rolf Krause6, Angelo Auricchio7. 1. Faculty of Medicine, Maastricht University, Maastricht, the Netherlands. 2. Center for Computational Medicine in Cardiology, Institute of Computational Science, Università della Svizzera italiana, Lugano, Switzerland. Electronic address: mark@potse.nl. 3. Division of Cardiology, Fondazione Cardiocentro Ticino, Lugano, Switzerland. 4. Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy. 5. Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, the Netherlands. 6. Center for Computational Medicine in Cardiology, Institute of Computational Science, Università della Svizzera italiana, Lugano, Switzerland. 7. Center for Computational Medicine in Cardiology, Institute of Computational Science, Università della Svizzera italiana, Lugano, Switzerland; Division of Cardiology, Fondazione Cardiocentro Ticino, Lugano, Switzerland.
Abstract
AIM: The aim of this study was to investigate the influence of geometrical factors on the ECG morphology and vectorcardiogram (VCG) parameters. METHODS: Patient-tailored models based on five heart-failure patients with intraventricular conduction defects (IVCDs) were created. The heart was shifted up to 6 cm to the left, right, up, and down and rotated ±30° around the anteroposterior axis. Precordial electrodes were shifted 3 cm down. RESULTS: Geometry modifications strongly altered ECG notching/slurring and intrinsicoid deflection time. Maximum VCG parameter changes were small for QRS duration (-6% to +10%) and QRS-T angle (-6% to +3%), but considerable for QRS amplitude (-36% to +59%), QRS area (-37% to +42%), T-wave amplitude (-41% to +36%), and T-wave area (-42% to +33%). CONCLUSION: The position of the heart with respect to the electrodes is an important factor determining notching/slurring and voltage-dependent parameters and therefore must be considered for accurate diagnosis of IVCDs.
AIM: The aim of this study was to investigate the influence of geometrical factors on the ECG morphology and vectorcardiogram (VCG) parameters. METHODS:Patient-tailored models based on five heart-failurepatients with intraventricular conduction defects (IVCDs) were created. The heart was shifted up to 6 cm to the left, right, up, and down and rotated ±30° around the anteroposterior axis. Precordial electrodes were shifted 3 cm down. RESULTS: Geometry modifications strongly altered ECG notching/slurring and intrinsicoid deflection time. Maximum VCG parameter changes were small for QRS duration (-6% to +10%) and QRS-T angle (-6% to +3%), but considerable for QRS amplitude (-36% to +59%), QRS area (-37% to +42%), T-wave amplitude (-41% to +36%), and T-wave area (-42% to +33%). CONCLUSION: The position of the heart with respect to the electrodes is an important factor determining notching/slurring and voltage-dependent parameters and therefore must be considered for accurate diagnosis of IVCDs.
Authors: C Sánchez; G D'Ambrosio; F Maffessanti; E G Caiani; F W Prinzen; R Krause; A Auricchio; M Potse Journal: Med Biol Eng Comput Date: 2017-08-19 Impact factor: 2.602
Authors: Jonathan P Cranford; Thomas J O'Hara; Christopher T Villongco; Omar M Hafez; Robert C Blake; Joseph Loscalzo; Jean-Luc Fattebert; David F Richards; Xiaohua Zhang; James N Glosli; Andrew D McCulloch; David E Krummen; Felice C Lightstone; Sergio E Wong Journal: Cardiovasc Eng Technol Date: 2018-03-16 Impact factor: 2.495
Authors: Zachi I Attia; Christopher V DeSimone; John J Dillon; Yehu Sapir; Virend K Somers; Jennifer L Dugan; Charles J Bruce; Michael J Ackerman; Samuel J Asirvatham; Bryan L Striemer; Jan Bukartyk; Christopher G Scott; Kevin E Bennet; Dorothy J Ladewig; Emily J Gilles; Dan Sadot; Amir B Geva; Paul A Friedman Journal: J Am Heart Assoc Date: 2016-01-25 Impact factor: 5.501