Literature DB >> 26025125

Fine mapping of the myosin light chain kinase (MYLK) gene replicates the association with asthma in populations of Spanish descent.

Marialbert Acosta-Herrera1, Maria Pino-Yanes2, Shwu-Fan Ma3, Amalia Barreto-Luis4, Almudena Corrales4, José Cumplido5, Eva Pérez-Rodríguez6, Paloma Campo7, Celeste Eng8, José Carlos García-Robaina6, Inés Quintela9, Jesús Villar10, Miguel Blanca7, Ángel Carracedo11, Teresa Carrillo5, Joe G N Garcia12, Dara G Torgerson8, Esteban G Burchard13, Carlos Flores14.   

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Year:  2015        PMID： 26025125      PMCID： PMC4699578          DOI： 10.1016/j.jaci.2015.04.025

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN： 0091-6749            Impact factor:   10.793


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  11 in total

1.  Airway structural alterations selectively associated with severe asthma.

Authors:  Laurent Benayoun; Anne Druilhe; Marie-Christine Dombret; Michel Aubier; Marina Pretolani
Journal:  Am J Respir Crit Care Med       Date:  2003-01-16       Impact factor: 21.405

2.  HLA-DRB1*15:01 allele protects from asthma susceptibility.

Authors:  María Pino-Yanes; Almudena Corrales; Marialbert Acosta-Herrera; Eva Pérez-Rodríguez; José Cumplido; Paloma Campo; Amalia Barreto-Luis; Florentino Sánchez-García; Tobías Felipe; Inmaculada Sánchez-Machín; Inés Quintela; José Carlos García-Robaina; Jesús Villar; Miguel Blanca; Angel Carracedo; Teresa Carrillo; Carlos Flores
Journal:  J Allergy Clin Immunol       Date:  2014-07-14       Impact factor: 10.793

3.  Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.

Authors:  Joshua M Galanter; Christopher R Gignoux; Dara G Torgerson; Lindsey A Roth; Celeste Eng; Sam S Oh; Elizabeth A Nguyen; Katherine A Drake; Scott Huntsman; Donglei Hu; Saunak Sen; Adam Davis; Harold J Farber; Pedro C Avila; Emerita Brigino-Buenaventura; Michael A LeNoir; Kelley Meade; Denise Serebrisky; Luisa N Borrell; William Rodríguez-Cintrón; Andres Moreno Estrada; Karla Sandoval Mendoza; Cheryl A Winkler; William Klitz; Isabelle Romieu; Stephanie J London; Frank Gilliland; Fernando Martinez; Carlos Bustamante; L Keoki Williams; Rajesh Kumar; José R Rodríguez-Santana; Esteban G Burchard
Journal:  J Allergy Clin Immunol       Date:  2014-01-07       Impact factor: 10.793

4.  Case-control admixture mapping in Latino populations enriches for known asthma-associated genes.

Authors:  Dara G Torgerson; Christopher R Gignoux; Joshua M Galanter; Katherine A Drake; Lindsey A Roth; Celeste Eng; Scott Huntsman; Raul Torres; Pedro C Avila; Rocio Chapela; Jean G Ford; José R Rodríguez-Santana; William Rodríguez-Cintrón; Ryan D Hernandez; Esteban G Burchard
Journal:  J Allergy Clin Immunol       Date:  2012-04-13       Impact factor: 10.793

5.  Myosin light chain kinase in endothelium: molecular cloning and regulation.

Authors:  J G Garcia; V Lazar; L I Gilbert-McClain; P J Gallagher; A D Verin
Journal:  Am J Respir Cell Mol Biol       Date:  1997-05       Impact factor: 6.914

6.  A variant of the myosin light chain kinase gene is associated with severe asthma in African Americans.

Authors:  Carlos Flores; Shwu-Fan Ma; Karen Maresso; Carole Ober; Joe G N Garcia
Journal:  Genet Epidemiol       Date:  2007-05       Impact factor: 2.135

7.  Polymorphisms in the myosin light chain kinase gene that confer risk of severe sepsis are associated with a lower risk of asthma.

Authors:  Li Gao; Audrey V Grant; Nicholas Rafaels; Maria Stockton-Porter; Tonya Watkins; Peisong Gao; Peter Chi; Melba Muñoz; Harold Watson; Georgia Dunston; Alkis Togias; Nadia Hansel; Jonathan Sevransky; James P Maloney; Marc Moss; Carl Shanholtz; Roy Brower; Joe G N Garcia; Dmitry N Grigoryev; Christopher Cheadle; Terri H Beaty; Rasika A Mathias; Kathleen C Barnes
Journal:  J Allergy Clin Immunol       Date:  2007-05       Impact factor: 10.793

8.  Gene flow from North Africa contributes to differential human genetic diversity in southern Europe.

Authors:  Laura R Botigué; Brenna M Henn; Simon Gravel; Brian K Maples; Christopher R Gignoux; Erik Corona; Gil Atzmon; Edward Burns; Harry Ostrer; Carlos Flores; Jaume Bertranpetit; David Comas; Carlos D Bustamante
Journal:  Proc Natl Acad Sci U S A       Date:  2013-06-03       Impact factor: 11.205

9.  A large-scale, consortium-based genomewide association study of asthma.

Authors:  Miriam F Moffatt; Ivo G Gut; Florence Demenais; David P Strachan; Emmanuelle Bouzigon; Simon Heath; Erika von Mutius; Martin Farrall; Mark Lathrop; William O C M Cookson
Journal:  N Engl J Med       Date:  2010-09-23       Impact factor: 91.245

10.  A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.

Authors:  Klaus Bønnelykke; Patrick Sleiman; Kasper Nielsen; Eskil Kreiner-Møller; Josep M Mercader; Danielle Belgrave; Herman T den Dekker; Anders Husby; Astrid Sevelsted; Grissel Faura-Tellez; Li Juel Mortensen; Lavinia Paternoster; Richard Flaaten; Anne Mølgaard; David E Smart; Philip F Thomsen; Morten A Rasmussen; Silvia Bonàs-Guarch; Claus Holst; Ellen A Nohr; Rachita Yadav; Michael E March; Thomas Blicher; Peter M Lackie; Vincent W V Jaddoe; Angela Simpson; John W Holloway; Liesbeth Duijts; Adnan Custovic; Donna E Davies; David Torrents; Ramneek Gupta; Mads V Hollegaard; David M Hougaard; Hakon Hakonarson; Hans Bisgaard
Journal:  Nat Genet       Date:  2013-11-17       Impact factor: 38.330
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  6 in total

1.  Mechanical Stress and Single Nucleotide Variants Regulate Alternative Splicing of the MYLK Gene.

Authors:  Joseph B Mascarenhas; Alex Y Tchourbanov; Hanli Fan; Sergei M Danilov; Ting Wang; Joe G N Garcia
Journal:  Am J Respir Cell Mol Biol       Date:  2017-01       Impact factor: 6.914

2.  Nonmuscle myosin light chain kinase activity modulates radiation-induced lung injury.

Authors:  Ting Wang; Biji Mathew; Xiaomin Wu; Yuka Shimizu; Alicia N Rizzo; Steven M Dudek; Ralph R Weichselbaum; Jeffrey R Jacobson; Louise Hecker; Joe G N Garcia
Journal:  Pulm Circ       Date:  2016-06       Impact factor: 3.017

Review 3.  Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets.

Authors:  Ting Wang; Christine Gross; Ankit A Desai; Evgeny Zemskov; Xiaomin Wu; Alexander N Garcia; Jeffrey R Jacobson; Jason X-J Yuan; Joe G N Garcia; Stephen M Black
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2016-12-15       Impact factor: 5.464

4.  Genetic and epigenetic regulation of the non-muscle myosin light chain kinase isoform by lung inflammatory factors and mechanical stress.

Authors:  Xiaoguang Sun; Belinda L Sun; Saad Sammani; Tadeo Bermudez; Steven M Dudek; Sara M Camp; Joe G N Garcia
Journal:  Clin Sci (Lond)       Date:  2021-04-16       Impact factor: 6.876

5.  Critical role for the lung endothelial nonmuscle myosin light-chain kinase isoform in the severity of inflammatory murine lung injury.

Authors:  Carrie L Kempf; Saad Sammani; Tadeo Bermudez; Jin H Song; Vivian Reyes Hernon; Matthew K Hufford; Jessica Burt; Sara M Camp; Steven M Dudek; Joe G N Garcia
Journal:  Pulm Circ       Date:  2022-04-07       Impact factor: 2.886

6.  Myosin light chain kinase ( MYLK) coding polymorphisms modulate human lung endothelial cell barrier responses via altered tyrosine phosphorylation, spatial localization, and lamellipodial protrusions.

Authors:  Ting Wang; Mary E Brown; Gabriel T Kelly; Sara M Camp; Joseph B Mascarenhas; Xiaoguang Sun; Steven M Dudek; Joe G N Garcia
Journal:  Pulm Circ       Date:  2018-02-26       Impact factor: 3.017
  6 in total

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