| Literature DB >> 26018359 |
Lijuan Tang1, Si Li1, Liguang Xu1, Wei Ma1, Hua Kuang1, Libing Wang1, Chuanlai Xu1.
Abstract
A novel biosensor for ultrasensitive detection of prostate-specific antigen (PSA) was established based on gold nanorod (Au NR) dimers assembly. The circular dichroism signal was significantly amplified by a silver shell depositing on the surface of the Au NR dimers. A low limit of detection of 0.076 aM and high specificity were observed within the range of 0.1 to 50 aM target PSA. The developed biosensor has the potential to serve as a general platform for the detection of cancer biomarkers.Entities:
Keywords: Au@Ag nanorod dimers; PSA detection; chirality
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Year: 2015 PMID: 26018359 DOI: 10.1021/acsami.5b01259
Source DB: PubMed Journal: ACS Appl Mater Interfaces ISSN: 1944-8244 Impact factor: 9.229