| Literature DB >> 26014934 |
Marcus Ho-Yin Wong1, Lizhang Liu1, Meiying Yan2, Edward Wai-Chi Chan1, Sheng Chen3.
Abstract
The extended-spectrum-β-lactamase (ESBL) determinant CTX-M-55 is increasingly prevalent in Escherichia coli but remains extremely rare in Salmonella. This study reports the isolation of a plasmid harboring the blaCTX-M-55 element in a clinical Salmonella enterica serotype Typhimurium strain resistant to multiple antibiotics. This plasmid is genetically identical to several known IncI2-type elements harbored by E. coli strains recovered from animals. This finding indicates that IncI2 plasmids harboring the blaCTX-M genes may undergo cross-species migration among potential bacterial pathogens, with E. coli as the major source of such elements.Entities:
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Year: 2015 PMID: 26014934 PMCID: PMC4505288 DOI: 10.1128/AAC.00775-15
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191