Literature DB >> 26013739

Effects of chitin and its derivatives on human cancer cells lines.

M Bouhenna1, R Salah1, R Bakour2, N Drouiche3,4, N Abdi1, H Grib1, H Lounici1,5, N Mameri1.   

Abstract

The present study is focused on the effect of chitin derivatives against human cancer cell lines RD and Hep2. As an outcome from this research, chitin was cytotoxic at IC50 = 400 μg/ml and 200 μg/ml against Hep2 cells and RD cells lines, respectively. Irradiated chitin had an IC50 value of 450 μg/ml for Hep2 and an IC50 of 200 μg/ml for RD. The lowest IC50 is attributed to chitosan, 300 μg/ml in Hep2 and 190 μg/ml in RD.

Entities:  

Keywords:  Biopolymers; Chitin; Chitosan; Cytotoxicity; Enzymatic hydrolysis

Mesh:

Substances:

Year:  2015        PMID: 26013739     DOI: 10.1007/s11356-015-4712-3

Source DB:  PubMed          Journal:  Environ Sci Pollut Res Int        ISSN: 0944-1344            Impact factor:   4.223


  10 in total

1.  Reporting degree of deacetylation values of chitosan: the influence of analytical methods.

Authors:  Tanveer Ahmad Khan; Kok Khiang Peh; Hung Seng Ch'ng
Journal:  J Pharm Pharm Sci       Date:  2002 Sep-Dec       Impact factor: 2.327

2.  Improved method for i.r. determination of the degree of N-acetylation of chitosan.

Authors:  A Baxter; M Dillon; K D Taylor; G A Roberts
Journal:  Int J Biol Macromol       Date:  1992-06       Impact factor: 6.953

3.  The biuret method of estimating albumin and globulin in serum and urine.

Authors:  J Fine
Journal:  Biochem J       Date:  1935-03       Impact factor: 3.857

4.  Bioactivity and biocompatibility of a chitosan-tobermorite composite membrane for guided tissue regeneration.

Authors:  A P Hurt; G Getti; N J Coleman
Journal:  Int J Biol Macromol       Date:  2013-12-01       Impact factor: 6.953

5.  Chitosan as a nasal delivery system: the effect of chitosan solutions on in vitro and in vivo mucociliary transport rates in human turbinates and volunteers.

Authors:  T J Aspden; J D Mason; N S Jones; J Lowe; O Skaugrud; L Illum
Journal:  J Pharm Sci       Date:  1997-04       Impact factor: 3.534

6.  Critical factors in chitin production by fermentation of shrimp biowaste.

Authors:  M S Rao; J Muñoz; W F Stevens
Journal:  Appl Microbiol Biotechnol       Date:  2000-12       Impact factor: 4.813

7.  Anticancer activity of chemically prepared shrimp low molecular weight chitin evaluation with the human monocyte leukaemia cell line, THP-1.

Authors:  R Salah; P Michaud; F Mati; Z Harrat; H Lounici; N Abdi; N Drouiche; N Mameri
Journal:  Int J Biol Macromol       Date:  2012-10-17       Impact factor: 6.953

8.  Purification, characterization, and molecular cloning of an extracellular chitinase from Bacillus licheniformis stain LHH100 isolated from wastewater samples in Algeria.

Authors:  Hassiba Laribi-Habchi; Amel Bouanane-Darenfed; Nadjib Drouiche; André Pauss; Nabil Mameri
Journal:  Int J Biol Macromol       Date:  2014-10-27       Impact factor: 6.953

9.  Bioadhesive drug delivery system using glyceryl monooleate for the intravesical administration of paclitaxel.

Authors:  Seung-Ju Lee; Sae Woong Kim; Hesson Chung; Yeong Taek Park; Young Wook Choi; Yong-Hyun Cho; Moon Soo Yoon
Journal:  Chemotherapy       Date:  2005-10-13       Impact factor: 2.544

10.  Tumouricidal activity of gilthead seabream (Sparus aurata L.) natural cytotoxic cells: the role played in vitro and in vivo by retinol acetate.

Authors:  A Cuesta; M A Esteban; J Meseguer
Journal:  Fish Shellfish Immunol       Date:  2003-02       Impact factor: 4.581

  10 in total
  8 in total

1.  Levofloxacin is phytotoxic and modifies the protein profile of lupin seedlings.

Authors:  Aleksandra Orzoł; Agnieszka I Piotrowicz-Cieślak
Journal:  Environ Sci Pollut Res Int       Date:  2017-08-10       Impact factor: 4.223

2.  Production of Chitin from Penaeus vannamei By-Products to Pilot Plant Scale Using a Combination of Enzymatic and Chemical Processes and Subsequent Optimization of the Chemical Production of Chitosan by Response Surface Methodology.

Authors:  José A Vázquez; Patrícia Ramos; Jesús Mirón; Jesus Valcarcel; Carmen G Sotelo; Ricardo I Pérez-Martín
Journal:  Mar Drugs       Date:  2017-06-16       Impact factor: 5.118

3.  Preparation and Characterization of Chitosan Obtained from Shells of Shrimp (Litopenaeus vannamei Boone).

Authors:  Rayane Santa Cruz Martins de Queiroz Antonino; Bianca Rosa Paschoal Lia Fook; Vítor Alexandre de Oliveira Lima; Raid Ícaro de Farias Rached; Eunice Paloma Nascimento Lima; Rodrigo José da Silva Lima; Carlos Andrés Peniche Covas; Marcus Vinícius Lia Fook
Journal:  Mar Drugs       Date:  2017-05-15       Impact factor: 5.118

4.  Improving the Functional Activities of Curcumin Using Milk Proteins as Nanocarriers.

Authors:  Soad Taha; Ibrahim El-Sherbiny; Toshiki Enomoto; Aida Salem; Emiko Nagai; Ahmed Askar; Ghada Abady; Mahmoud Abdel-Hamid
Journal:  Foods       Date:  2020-07-24

Review 5.  Extraction of Nanochitin from Marine Resources and Fabrication of Polymer Nanocomposites: Recent Advances.

Authors:  Blessy Joseph; Rubie Mavelil Sam; Preetha Balakrishnan; Hanna J Maria; Sreeraj Gopi; Tatiana Volova; Susana C M Fernandes; Sabu Thomas
Journal:  Polymers (Basel)       Date:  2020-07-27       Impact factor: 4.329

Review 6.  Dual Role of Chitin as the Double Edged Sword in Controlling the NLRP3 Inflammasome Driven Gastrointestinal and Gynaecological Tumours.

Authors:  Chetan Roger Dhanjal; Rathnamegha Lingamsetty; Anooshka Pareddy; Se-Kwon Kim; Ritu Raval
Journal:  Mar Drugs       Date:  2022-07-11       Impact factor: 6.085

7.  Chitin-Induced Airway Epithelial Cell Innate Immune Responses Are Inhibited by Carvacrol/Thymol.

Authors:  Ali Reza Khosravi; David J Erle
Journal:  PLoS One       Date:  2016-07-27       Impact factor: 3.240

8.  A comparison of chitosan properties after extraction from shrimp shells by diluted and concentrated acids.

Authors:  Mohammed Eddya; Bouazza Tbib; Khalil El-Hami
Journal:  Heliyon       Date:  2020-02-27
  8 in total

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