Literature DB >> 26013050

The proportional odds cumulative incidence model for competing risks.

Frank Eriksson1, Jianing Li2, Thomas Scheike1, Mei-Jie Zhang2.   

Abstract

We suggest an estimator for the proportional odds cumulative incidence model for competing risks data. The key advantage of this model is that the regression parameters have the simple and useful odds ratio interpretation. The model has been considered by many authors, but it is rarely used in practice due to the lack of reliable estimation procedures. We suggest such procedures and show that their performance improve considerably on existing methods. We also suggest a goodness-of-fit test for the proportional odds assumption. We derive the large sample properties and provide estimators of the asymptotic variance. The method is illustrated by an application in a bone marrow transplant study and the finite-sample properties are assessed by simulations.
© 2015, The International Biometric Society.

Entities:  

Keywords:  Competing risks; Estimating equations; Flexible modeling; Linear transformation model; Odds ratio; Proportional odds model; Semiparametric; Survival

Mesh:

Year:  2015        PMID: 26013050      PMCID: PMC4608382          DOI: 10.1111/biom.12330

Source DB:  PubMed          Journal:  Biometrics        ISSN: 0006-341X            Impact factor:   2.571


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