Literature DB >> 26009548

Examining Determinants of Radiotherapy Access: Do Cost and Radiotherapy Inconvenience Affect Uptake of Breast-conserving Treatment for Early Breast Cancer?

J Lam1, T Cook2, S Foster1, R Poon3, C Milross4, P Sundaresan5.   

Abstract

AIMS: Radiotherapy utilisation is likely affected by multiple factors pertaining to radiotherapy access. Radiotherapy is an integral component of breast-conserving treatment (BCT) for early breast cancer. We aimed to determine if stepwise improvements in radiotherapy access in regional Australia affected the uptake of BCT and thus radiotherapy.
MATERIALS AND METHODS: Breast cancer operations in the Central Coast of New South Wales between January 2010 and March 2014 for T1-2N0-1M0 invasive or in situ (≤5 cm) disease in female patients eligible for BCT were examined. BCT uptake was calculated for three 1 year periods: period 1 (local radiotherapy available at cost to user or out of area radiotherapy with travel cost and inconvenience); period 2 (as per period 1 + publicly funded transport and radiotherapy at out of area facilities at no cost to user); period 3 (as per period 1 + publicly funded local radiotherapy at no cost to user).
RESULTS: In total, 574 cases met eligibility criteria. BCT declined with increasing distance to publicly funded radiotherapy (P = 0.035). BCT rates for periods 1, 2 and 3 were 63% (113/180), 61% (105/173) and 71% (156/221). There were no statistically significant differences in BCT between periods 1 and 2 in the whole cohort or within age, histology or tumour size subgroups. Overall, there was a 9% increase in BCT in the whole cohort in period 3 compared with periods 1 and 2 (P = 0.031). This increase was statistically significant for women over 70 years (19% increase, P = 0.034), for women with ductal carcinoma in situ (25% increase, P = 0.013) and for women with primary tumours that were ≤10 mm (21% increase, P = 0.016).
CONCLUSIONS: Improving the affordability of radiotherapy through publicly funded transport and radiotherapy at out of area facilities did not improve BCT uptake in a region where radiotherapy was locally available, albeit at cost to the user. Improving both affordability and convenience through the provision of local publicly funded radiotherapy increased BCT uptake. Service availability and affordability have long been recognised as important determinants of radiotherapy access. Our findings suggest that inconvenience may also influence radiotherapy utilisation. Crown
Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Access; availability; cost; inconvenience; radiotherapy; utilisation

Mesh:

Year:  2015        PMID: 26009548     DOI: 10.1016/j.clon.2015.04.034

Source DB:  PubMed          Journal:  Clin Oncol (R Coll Radiol)        ISSN: 0936-6555            Impact factor:   4.126


  12 in total

1.  Phase 1 in the development of a patient-reported measure to quantify perceived inconvenience of radiotherapy: generation of issues.

Authors:  P Sundaresan; C G Milross; M R Stockler; D S J Costa; M T King
Journal:  Qual Life Res       Date:  2016-03-15       Impact factor: 4.147

2.  Daily Fractionation of External Beam Accelerated Partial Breast Irradiation to 40 Gy Is Well Tolerated and Locally Effective.

Authors:  Lior Z Braunstein; Maria Thor; Jessica Flynn; Zachary Cost; Molly Wilgucki; Shalom Rosenbaum; Zhigang Zhang; Erin Gillespie; Beryl McCormick; Atif Khan; Alice Ho; Oren Cahlon; Joseph O Deasy; Simon N Powell
Journal:  Int J Radiat Oncol Biol Phys       Date:  2019-03-07       Impact factor: 7.038

3.  Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial.

Authors:  Frank A Vicini; Reena S Cecchini; Julia R White; Douglas W Arthur; Thomas B Julian; Rachel A Rabinovitch; Robert R Kuske; Patricia A Ganz; David S Parda; Michael F Scheier; Kathryn A Winter; Soonmyung Paik; Henry M Kuerer; Laura A Vallow; Lori J Pierce; Eleftherios P Mamounas; Beryl McCormick; Joseph P Costantino; Harry D Bear; Isabelle Germain; Gregory Gustafson; Linda Grossheim; Ivy A Petersen; Richard S Hudes; Walter J Curran; John L Bryant; Norman Wolmark
Journal:  Lancet       Date:  2019-12-05       Impact factor: 79.321

4.  Environmental and social benefits of the targeted intraoperative radiotherapy for breast cancer: data from UK TARGIT-A trial centres and two UK NHS hospitals offering TARGIT IORT.

Authors:  Nathan J Coombs; Joel M Coombs; Uma J Vaidya; Julian Singer; Max Bulsara; Jeffrey S Tobias; Frederik Wenz; David J Joseph; Douglas A Brown; Richard Rainsbury; Tim Davidson; Douglas J A Adamson; Samuele Massarut; David Morgan; Ingrid Potyka; Tammy Corica; Mary Falzon; Norman Williams; Michael Baum; Jayant S Vaidya
Journal:  BMJ Open       Date:  2016-05-09       Impact factor: 2.692

5.  Variations in outcomes by residential location for women with breast cancer: a systematic review.

Authors:  Paramita Dasgupta; Peter D Baade; Danny R Youlden; Gail Garvey; Joanne F Aitken; Isabella Wallington; Jennifer Chynoweth; Helen Zorbas; Philippa H Youl
Journal:  BMJ Open       Date:  2018-04-29       Impact factor: 2.692

Review 6.  Dosimetric evaluation and systematic review of radiation therapy techniques for early stage node-negative breast cancer treatment.

Authors:  Tabitha Y Chan; Johann I Tang; Poh Wee Tan; Neill Roberts
Journal:  Cancer Manag Res       Date:  2018-10-23       Impact factor: 3.989

7.  Geographical Inequalities in Surgical Treatment for Localized Female Breast Cancer, Queensland, Australia 1997-2011: Improvements over Time but Inequalities Remain.

Authors:  Peter D Baade; Paramita Dasgupta; Philippa H Youl; Christopher Pyke; Joanne F Aitken
Journal:  Int J Environ Res Public Health       Date:  2016-07-19       Impact factor: 3.390

8.  What might explain deprivation-specific differences in the excess hazard of breast cancer death amongst screen-detected women? Analysis of patients diagnosed in the West Midlands region of England from 1989 to 2011.

Authors:  Melanie Morris; Laura M Woods; Bernard Rachet
Journal:  Oncotarget       Date:  2016-08-02

9.  Are Patients Traveling for Intraoperative Radiation Therapy?

Authors:  Kelsey E Larson; Stephanie A Valente; Chirag Shah; Rahul D Tendulkar; Sheen Cherian; Courtney Yanda; Chao Tu; Jessica Echle; Stephen R Grobmyer
Journal:  Int J Breast Cancer       Date:  2017-10-09

10.  Hypofractionated radiation therapy comparing a standard radiotherapy schedule (over 3 weeks) with a novel 1-week schedule in adjuvant breast cancer: an open-label randomized controlled study (HYPORT-Adjuvant)-study protocol for a multicentre, randomized phase III trial.

Authors:  Sanjoy Chatterjee; Santam Chakraborty
Journal:  Trials       Date:  2020-09-30       Impact factor: 2.279

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