Alejandra Soto1, Ximena Avila2, Pia Cordova3, Pola Fernandez3, Mariela Lopez3, Lorenzo A Villa3, Felipe Morales4. 1. CESFAM Bicentenario, Arauco, Chile. 2. Pharmacovigilance Unit, San Vicente Hospital, Arauco, Chile. 3. Facultad de Farmacia, Universidad de Concepción, Barrio Universitario, 4030000, Concepción, Chile. 4. Facultad de Farmacia, Universidad de Concepción, Barrio Universitario, 4030000, Concepción, Chile. felimora@udec.cl.
Abstract
BACKGROUND: Non-adherence to prescribed treatment is a principle cause of treatment failure in patients with chronic diseases, such as type 2 diabetes mellitus (T2DM) and hypertension. Improved patient monitoring and education have been shown to improve adherence and clinical outcomes. OBJECTIVE: This study evaluates the impact of a pharmacotherapy optimization plan centered on patient education that was implemented at a hospital in Arauco, Chile. METHODS: A prospective study was conducted using 50 randomly selected patients diagnosed with both T2DM and hypertension. Each patient participated in three successive interview sessions over 6 months. At each session, the following variables were evaluated by a pharmacist: blood pressure, HbA1c, adherence to prescribed medication, and patient knowledge of disease. RESULTS: Significant decreases were observed for HbA1c (<0.001), and SBP (<0.001), with stronger and more significant decreases observed for females. Patient adherence to prescribed medication also improved, but not significantly. The number of patients with full knowledge of their diseases increased significantly (p < 0.001) from 10 to 66%. CONCLUSION: This study suggests that the incorporation of a pharmacotherapeutic optimization plan for patients with chronic diseases can have a positive impact on the control of chronic diseases, such as T2DM and hypertension.
BACKGROUND: Non-adherence to prescribed treatment is a principle cause of treatment failure in patients with chronic diseases, such as type 2 diabetes mellitus (T2DM) and hypertension. Improved patient monitoring and education have been shown to improve adherence and clinical outcomes. OBJECTIVE: This study evaluates the impact of a pharmacotherapy optimization plan centered on patient education that was implemented at a hospital in Arauco, Chile. METHODS: A prospective study was conducted using 50 randomly selected patients diagnosed with both T2DM and hypertension. Each patient participated in three successive interview sessions over 6 months. At each session, the following variables were evaluated by a pharmacist: blood pressure, HbA1c, adherence to prescribed medication, and patient knowledge of disease. RESULTS: Significant decreases were observed for HbA1c (<0.001), and SBP (<0.001), with stronger and more significant decreases observed for females. Patient adherence to prescribed medication also improved, but not significantly. The number of patients with full knowledge of their diseases increased significantly (p < 0.001) from 10 to 66%. CONCLUSION: This study suggests that the incorporation of a pharmacotherapeutic optimization plan for patients with chronic diseases can have a positive impact on the control of chronic diseases, such as T2DM and hypertension.
Entities:
Keywords:
Chile; Medication adherence; Patient education; Pharmacotherapeutic optimization plan
Authors: Marie Manteuffel; Sophy Williams; William Chen; Robert R Verbrugge; Donald G Pittman; Amy Steinkellner Journal: J Womens Health (Larchmt) Date: 2013-11-08 Impact factor: 2.681
Authors: Sieta T de Vries; Joost C Keers; Rosalie Visser; Dick de Zeeuw; Flora M Haaijer-Ruskamp; Jaco Voorham; Petra Denig Journal: J Psychosom Res Date: 2013-11-13 Impact factor: 3.006
Authors: José M Castellano; Ginés Sanz; José L Peñalvo; Sameer Bansilal; Antonio Fernández-Ortiz; Luz Alvarez; Luis Guzmán; Juan Carlos Linares; Fernando García; Fabiana D'Aniello; Joan Albert Arnáiz; Sara Varea; Felipe Martínez; Alberto Lorenzatti; Iñaki Imaz; Luis M Sánchez-Gómez; Maria Carla Roncaglioni; Marta Baviera; Sidney C Smith; Kathryn Taubert; Stuart Pocock; Carlos Brotons; Michael E Farkouh; Valentin Fuster Journal: J Am Coll Cardiol Date: 2014-09-01 Impact factor: 24.094
Authors: Louise Foley; James Larkin; Richard Lombard-Vance; Andrew W Murphy; Lisa Hynes; Emer Galvin; Gerard J Molloy Journal: BMJ Open Date: 2021-09-02 Impact factor: 3.006