Joanna Kaluza1, Agneta Åkesson2, Alicja Wolk2. 1. Department of Human Nutrition, Warsaw University of Life Sciences - SGGW, Warsaw, Poland; Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: joanna_kaluza@sggw.pl. 2. Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Abstract
BACKGROUND: Epidemiologic studies of red meat consumption in relation to risk of heart failure (HF) are limited. We examined the associations between long-term unprocessed red meat and processed red meat consumption and incidence of HF in women. METHODS: The population-based prospective Swedish Mammography Cohort included 34,057 women, aged 48-83 years, with no history of HF or ischemic heart disease at baseline (in 1997). Meat consumption was assessed using a self-administered food-frequency questionnaire (FFQ) in 1997 as well as FFQ administered in 1987-90. Cox proportional hazard regression models were used to estimate hazard ratios (HRs) with 95% confidence intervals (CIs). RESULTS: During a mean follow-up of 13.2 years, 2806 women were diagnosed with HF. Consumption of processed meat (FFQ 1997) was statistically significant positively associated with HF incidence. Women who consumed ≥ 50 g/day processed red meat compared to those who consumed < 25 g/day had a 1.23 (95% CI: 1.09-1.39, P-trend=0.003) higher risk of HF. Long-term high consumption of processed red meat (average from 1987 to 1997) ≥ 50 g/day in comparison to < 25 g/day was associated with HR: 1.30 (95% CI: 1.05-1.60, P-trend=0.002). Women who consistently consumed (in both 1987 and 1997) ≥ 50 g/day vs. < 25 g/day had a 1.78 (95% CI: 1.00-3.16) higher risk of HF. Consumption of unprocessed meat was not associated with increased risk of HF incidence. CONCLUSIONS: Findings from this prospective study of women indicate that processed red meat, but not unprocessed red meat, consumption is associated with an increased risk of HF incidence.
BACKGROUND: Epidemiologic studies of red meat consumption in relation to risk of heart failure (HF) are limited. We examined the associations between long-term unprocessed red meat and processed red meat consumption and incidence of HF in women. METHODS: The population-based prospective Swedish Mammography Cohort included 34,057 women, aged 48-83 years, with no history of HF or ischemic heart disease at baseline (in 1997). Meat consumption was assessed using a self-administered food-frequency questionnaire (FFQ) in 1997 as well as FFQ administered in 1987-90. Cox proportional hazard regression models were used to estimate hazard ratios (HRs) with 95% confidence intervals (CIs). RESULTS: During a mean follow-up of 13.2 years, 2806 women were diagnosed with HF. Consumption of processed meat (FFQ 1997) was statistically significant positively associated with HF incidence. Women who consumed ≥ 50 g/day processed red meat compared to those who consumed < 25 g/day had a 1.23 (95% CI: 1.09-1.39, P-trend=0.003) higher risk of HF. Long-term high consumption of processed red meat (average from 1987 to 1997) ≥ 50 g/day in comparison to < 25 g/day was associated with HR: 1.30 (95% CI: 1.05-1.60, P-trend=0.002). Women who consistently consumed (in both 1987 and 1997) ≥ 50 g/day vs. < 25 g/day had a 1.78 (95% CI: 1.00-3.16) higher risk of HF. Consumption of unprocessed meat was not associated with increased risk of HF incidence. CONCLUSIONS: Findings from this prospective study of women indicate that processed red meat, but not unprocessed red meat, consumption is associated with an increased risk of HF incidence.
Authors: Feiby L Nassan; Yu-Han Chiu; Jose C Vanegas; Audrey J Gaskins; Paige L Williams; Jennifer B Ford; Jill Attaman; Russ Hauser; Jorge E Chavarro Journal: Am J Clin Nutr Date: 2018-11-01 Impact factor: 7.045
Authors: Heli E K Virtanen; Sari Voutilainen; Timo T Koskinen; Jaakko Mursu; Tomi-Pekka Tuomainen; Jyrki K Virtanen Journal: Circ Heart Fail Date: 2018-06 Impact factor: 8.790
Authors: Rocío Ortiz-Moncada; María Morales-Suárez-Varela; Ángeles Avecilla-Benítez; Aurora Norte Navarro; Rocío Olmedo-Requena; Carmen Amezcua-Prieto; José M Cancela; Gemma Blázquez Abellán; Ramona Mateos-Campos; Luis Félix Valero Juan; Susana Redondo Martín; Jéssica Alonso-Molero; Antonio José Molina de la Torre; Agustín Llopis-Morales; Isabel Peraita-Costa; Tania Fernández-Villa Journal: Int J Environ Res Public Health Date: 2019-10-15 Impact factor: 3.390