Literature DB >> 25994874

Lightweight application for generating clinical research information systems: MAGIC.

Brane Leskošek1,2, Marjan Pajntar3.   

Abstract

BACKGROUND: Our purpose was to build and test a lightweight solution for generating clinical research information systems (CRIS) that would allow non-IT professionals with basic knowledge of computer usage to quickly define and build a ready-to-use, safe and secure web-based clinical research system for data management. We use the acronym MAGIC (Medical Application Generator InteraCtive) for the system.
METHODS: The generated CRIS should be very easy to build and use, so a common LAMP (Linux Apache MySQL Perl) platform was used, which also enables short development cycles. The application was built and tested using eXtreme Programming (XP) principles by a small development team consisting of one informatics specialist, one physician and one graphical designer/programmer.
RESULTS: The parameter and graphical user interface (GUI) definitions for the CRIS can be made by non-IT professionals using an intuitive English-language-like formalism called application definition language (ADL). From these definitions, the MAGIC builds an end-user CRIS that can be used on a wide variety of platforms (from standard workstations to hand-held devices). A working example of a national health-care-quality assessment program is presented to illustrate this process.
CONCLUSION: The lightweight application for generating CRIS (MAGIC) has proven to be useful for both clinical and analytical users in real working environment. To achieve better performance and interoperability, we are planning to recompile the application using XML schemas (XSD) in HL7 CDA or openEHR archetypes formats used for parameters definition and for data interchange between different information systems.

Entities:  

Keywords:  Clinical research informatics; Clinical trial; Electronic health record; Information system; Interoperability

Mesh:

Year:  2015        PMID: 25994874     DOI: 10.1007/s00508-015-0794-7

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN: 0043-5325            Impact factor:   1.704


  18 in total

1.  Testing Three Problem List Terminologies in a simulated data entry environment.

Authors:  Kin Wah Fung; Junchuan Xu; S Trent Rosenbloom; David Mohr; Naveen Maram; Thomas Suther
Journal:  AMIA Annu Symp Proc       Date:  2011-10-22

2.  Evaluation of HL7 v2.5.1 electronic case reports transmitted from a healthcare enterprise to public health.

Authors:  Deepthi Rajeev; Catherine Staes; R Scott Evans; Andrea Price; Mary Hill; Susan Mottice; Ilene Risk; Robert Rolfs
Journal:  AMIA Annu Symp Proc       Date:  2011-10-22

3.  Building co-operative bibliographic databases in European bioethics: a contribution from EU New Member States.

Authors:  Jure Dimec; Branimir Leskosek
Journal:  Comput Methods Programs Biomed       Date:  2007-06-15       Impact factor: 5.428

4.  Archetype-based knowledge management for semantic interoperability of electronic health records.

Authors:  Sebastian Garde; Rong Chen; Heather Leslie; Thomas Beale; Ian McNicoll; Sam Heard
Journal:  Stud Health Technol Inform       Date:  2009

5.  On selecting a clinical trial management system for large scale, multi-centre, multi-modal clinical research study.

Authors:  Hugo Leroux; Simon McBride; Simon Gibson
Journal:  Stud Health Technol Inform       Date:  2011

6.  Possible combinations of electronic data capture and randomization systems. principles and the realization with RANDI2 and OpenClinica.

Authors:  D Schrimpf; M Haag; L R Pilz
Journal:  Methods Inf Med       Date:  2014-02-11       Impact factor: 2.176

7.  The process of installing REDCap, a web based database supporting biomedical research: the first year.

Authors:  M Klipin; I Mare; S Hazelhurst; B Kramer
Journal:  Appl Clin Inform       Date:  2014-11-19       Impact factor: 2.342

8.  [Medical informatics in research, teaching and patient management].

Authors:  K P Adlassnig
Journal:  Wien Klin Wochenschr       Date:  1995       Impact factor: 1.704

9.  The ClinicalTrials.gov results database--update and key issues.

Authors:  Deborah A Zarin; Tony Tse; Rebecca J Williams; Robert M Califf; Nicholas C Ide
Journal:  N Engl J Med       Date:  2011-03-03       Impact factor: 91.245

10.  ClinicalTrials.gov reporting: strategies for success at an academic health center.

Authors:  Erin K O'Reilly; Nancy J Hassell; Denise C Snyder; Susan Natoli; Irwin Liu; Jackie Rimmler; Valerie Amspacher; Bruce K Burnett; Amanda B Parrish; Jelena P Berglund; Mark Stacy
Journal:  Clin Transl Sci       Date:  2014-11-12       Impact factor: 4.689

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.