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Literature DB >> 2599437

Heartburn--the acid test.

Abstract

To determine whether symptoms of gastro-oesophageal reflux are related to the degree of oesophageal acid exposure, 190 patients (of 220 referred) with heartburn and acid regurgitation were compared with 50 normal subjects. A definite relationship between frequency of reflux symptoms and degree of oesophageal acid exposure was found both in patients with and without oesophagitis. We conclude that the frequency of gastro-oesophageal reflux symptoms is related to degree of oesophageal acid exposure.

Entities: Chemical Disease Species

Mesh：

Year: 1989 PMID： 2599437 PMCID： PMC1434330 DOI： 10.1136/gut.30.11.1523

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

6 in total

1. Reproducibility of ambulatory oesophageal pH monitoring.

Authors: F Johnsson; B Joelsson
Journal: Gut Date: 1988-07 Impact factor: 23.059

2. Management of dyspepsia: report of a working party.

Authors:
Journal: Lancet Date: 1988-03-12 Impact factor: 79.321

3. Symptoms and endoscopic findings in the diagnosis of gastroesophageal reflux disease.

Authors: F Johnsson; B Joelsson; K Gudmundsson; L Greiff
Journal: Scand J Gastroenterol Date: 1987-08 Impact factor: 2.423

4. The irritable oesophagus--a frequent cause of angina-like pain.

Authors: G Vantrappen; J Janssens; G Ghillebert
Journal: Lancet Date: 1987-05-30 Impact factor: 79.321

Review 5. Non-ulcer dyspepsia: potential causes and pathophysiology.

Authors: N J Talley; S F Phillips
Journal: Ann Intern Med Date: 1988-06 Impact factor: 25.391

6. Cimetidine responders in non-ulcer dyspepsia.

Authors: T Johannessen; U Fjøsne; P M Kleveland; T Halvorsen; P Kristensen; I Løge; P E Hafstad; P Sandbakken; H Petersen
Journal: Scand J Gastroenterol Date: 1988-04 Impact factor: 2.423

6 in total

19 in total

1. What is heartburn worth? A cost-utility analysis of management strategies.

Authors: G R Heudebert; R M Centor; J C Klapow; R Marks; L Johnson; C M Wilcox
Journal: J Gen Intern Med Date: 2000-03 Impact factor: 5.128

2. Clinical outcomes after laparoscopic antireflux surgery in patients with and without preoperative endoscopic esophagitis.

Authors: Ketan M Desai; Margaret M Frisella; Nathaniel J Soper
Journal: J Gastrointest Surg Date: 2003-01 Impact factor: 3.452

Review 3. Assessment of reflux symptom severity: methodological options and their attributes.

Authors: P Bytzer
Journal: Gut Date: 2004-05 Impact factor: 23.059

Review 4. Acupuncture for functional gastrointestinal disorders.

Authors: Toku Takahashi
Journal: J Gastroenterol Date: 2006-05 Impact factor: 7.527

5. Acid suppression: how much is needed?

Authors: D G Colin-Jones
Journal: BMJ Date: 1990-09-22

6. Relation between oesophageal acid exposure and healing of oesophagitis with omeprazole in patients with severe reflux oesophagitis.

Authors: R H Holloway; J Dent; F Narielvala; A M Mackinnon
Journal: Gut Date: 1996-05 Impact factor: 23.059

7. Quality-of-life assessments in evaluation of laparoscopic Rosetti fundoplication.

Authors: H Glise; B Hallerbäck; B Johansson
Journal: Surg Endosc Date: 1995-02 Impact factor: 4.584

8. Impaired gastric motility and its relationship to reflux symptoms in patients with nonerosive gastroesophageal reflux disease.

Authors: Takeshi Kamiya; Hiroshi Adachi; Makoto Hirako; Michiko Shikano; Eriko Matsuhisa; Tsuneya Wada; Naotaka Ogasawara; Shunsuke Nojiri; Hiromi Kataoka; Makoto Sasaki; Hirotaka Ohara; Takashi Joh
Journal: J Gastroenterol Date: 2009-02-13 Impact factor: 7.527

9. Esomeprazole 40 mg provides more effective intragastric acid control than lansoprazole 30 mg, omeprazole 20 mg, pantoprazole 40 mg and rabeprazole 20 mg in patients with gastro-oesophageal reflux symptoms.

Authors: Kerstin Röhss; Tore Lind; Clive Wilder-Smith
Journal: Eur J Clin Pharmacol Date: 2004-09-02 Impact factor: 2.953

10. Effect of increasing esomeprazole and pantoprazole doses on acid control in patients with symptoms of gastro-oesophageal reflux disease: a randomized, dose-response study.

Authors: Clive Wilder-Smith; Anna Backlund; Göran Eckerwall; Tore Lind; Mia Fjellman; Kerstin Röhss
Journal: Clin Drug Investig Date: 2008 Impact factor: 2.859