Literature DB >> 25994046

The ketogenic diet in pharmacoresistant childhood epilepsy.

Steven Parrish Winesett1, Stacey Kordecki Bessone, Eric H W Kossoff.   

Abstract

Available pharmacologic treatments for seizures are limited in their efficacy. For a patient with seizures, pharmacologic treatment with available anticonvulsant medications leads to seizure control in <70% of patients. Surgical resection can lead to control in a select subset of patients but still leaves a significant number of patients with uncontrolled seizures. The ketogenic diet and related diets have proven to be useful in pharmacoresistant childhood epilepsy.

Entities:  

Keywords:  GLUT-1 deficiency; MCT diet; doose syndrome; epilepsy; infantile spasms; ketogenic; lennox-gastaut syndrome; low glycemic index diet; modified atkins diet; seizures

Mesh:

Year:  2015        PMID: 25994046     DOI: 10.1586/14737175.2015.1044982

Source DB:  PubMed          Journal:  Expert Rev Neurother        ISSN: 1473-7175            Impact factor:   4.618


  16 in total

Review 1.  From Genetic Testing to Precision Medicine in Epilepsy.

Authors:  Pasquale Striano; Berge A Minassian
Journal:  Neurotherapeutics       Date:  2020-04       Impact factor: 7.620

Review 2.  Safety and tolerability of the ketogenic diet used for the treatment of refractory childhood epilepsy: a systematic review of published prospective studies.

Authors:  Qian-Yun Cai; Zhong-Jie Zhou; Rong Luo; Jing Gan; Shi-Ping Li; De-Zhi Mu; Chao-Min Wan
Journal:  World J Pediatr       Date:  2017-07-12       Impact factor: 2.764

3.  Ketogenic diet compromises vertebral microstructure and biomechanical characteristics in mice.

Authors:  Xiuhua Wu; Jianyang Ding; Xiaolin Xu; Xiaomeng Wang; Junhao Liu; Jie Jiang; Qi Liu; Ganggang Kong; Zucheng Huang; Zhou Yang; Qingan Zhu
Journal:  J Bone Miner Metab       Date:  2019-04-09       Impact factor: 2.626

Review 4.  β-Hydroxybutyrate: A Signaling Metabolite.

Authors:  John C Newman; Eric Verdin
Journal:  Annu Rev Nutr       Date:  2017-08-21       Impact factor: 11.848

Review 5.  Pharmacotherapy for Focal Seizures in Children and Adolescents.

Authors:  Clare E Stevens; Carl E Stafstrom
Journal:  Drugs       Date:  2018-09       Impact factor: 9.546

6.  Variability in Serum Concentrations and Clinical Response in Artisanal Versus Pharmaceutical Cannabidiol Treatment of Pediatric Pharmacoresistant Epilepsy.

Authors:  Nathan T Cohen; Burak Bahar; Joan A Conry; John M Schreiber
Journal:  J Pediatr Pharmacol Ther       Date:  2022-08-19

Review 7.  The Current Status of the Ketogenic Diet in Psychiatry.

Authors:  Emmanuelle C S Bostock; Kenneth C Kirkby; Bruce V M Taylor
Journal:  Front Psychiatry       Date:  2017-03-20       Impact factor: 4.157

Review 8.  New developments in the management of partial-onset epilepsy: role of brivaracetam.

Authors:  Giangennaro Coppola; Giulia Iapadre; Francesca Felicia Operto; Alberto Verrotti
Journal:  Drug Des Devel Ther       Date:  2017-03-06       Impact factor: 4.162

9.  Ketogenic diets, physical activity and body composition: a review.

Authors:  Damoon Ashtary-Larky; Reza Bagheri; Hoda Bavi; Julien S Baker; Tatiana Moro; Laura Mancin; Antonio Paoli
Journal:  Br J Nutr       Date:  2021-07-12       Impact factor: 4.125

10.  Ketogenic diet effects on 52 children with pharmacoresistant epileptic encephalopathy: A clinical prospective study.

Authors:  Qiong Wu; Hua Wang; Yu Ying Fan; Jun Mei Zhang; Xue Yan Liu; Xiu Ying Fang; Feng Hua Yang; Qing Jun Cao; Ying Qi
Journal:  Brain Behav       Date:  2018-04-18       Impact factor: 2.708

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