Literature DB >> 2598811

An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo.

R S Beddington1, E J Robertson.   

Abstract

Embryonic stem cells (ES) cells were injected into host blastocysts either in groups of 10-15 cells or as single cells in order to test their developmental potential in the developing embryo. The analysis of midgestation chimaeras, by electrophoretic separation of glucose phosphate isomerase (GPI) isozymes, showed that ES cells were capable of colonizing trophectoderm and primitive endoderm derivatives at a low frequency, as well as producing a high rate of chimaerism in tissues of the fetus and extraembryonic mesoderm.

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Year:  1989        PMID： 2598811     DOI： 10.1242/dev.105.4.733

Source DB:  PubMed          Journal:  Development        ISSN： 0950-1991            Impact factor:   6.868


  144 in total

1.  Asymmetric and node-specific nodal expression patterns are controlled by two distinct cis-acting regulatory elements.

Authors:  D P Norris; E J Robertson
Journal:  Genes Dev       Date:  1999-06-15       Impact factor: 11.361

2.  Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo.

Authors:  Lynn A Hanna; Ruth K Foreman; Illya A Tarasenko; Daniel S Kessler; Patricia A Labosky
Journal:  Genes Dev       Date:  2002-10-15       Impact factor: 11.361

3.  Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity.

Authors:  Tetsuya S Tanaka; Tilo Kunath; Wendy L Kimber; Saied A Jaradat; Carole A Stagg; Masayuki Usuda; Takashi Yokota; Hitoshi Niwa; Janet Rossant; Minoru S H Ko
Journal:  Genome Res       Date:  2002-12       Impact factor: 9.043

4.  FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse.

Authors:  P A Hoodless; M Pye; C Chazaud; E Labbé; L Attisano; J Rossant; J L Wrana
Journal:  Genes Dev       Date:  2001-05-15       Impact factor: 11.361

Review 5.  The topographical regulation of embryonic stem cell differentiation.

Authors:  Patricia Murray; David Edgar
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2004-06-29       Impact factor: 6.237

Review 6.  Understanding pancreas development for β-cell repair and replacement therapies.

Authors:  Aurelia Raducanu; Heiko Lickert
Journal:  Curr Diab Rep       Date:  2012-10       Impact factor: 4.810

7.  Bmp4 is required for the generation of primordial germ cells in the mouse embryo.

Authors:  K A Lawson; N R Dunn; B A Roelen; L M Zeinstra; A M Davis; C V Wright; J P Korving; B L Hogan
Journal:  Genes Dev       Date:  1999-02-15       Impact factor: 11.361

Review 8.  Pluripotent stem cells: origin, maintenance and induction.

Authors:  Maria P De Miguel; Sherezade Fuentes-Julián; Yago Alcaina
Journal:  Stem Cell Rev Rep       Date:  2010-12       Impact factor: 5.739

9.  Self-renewal and differentiation of mouse embryonic stem cells as measured by Oct4 expression: the role of the cAMP/PKA pathway.

Authors:  S Faherty; A Fitzgerald; M Keohan; L R Quinlan
Journal:  In Vitro Cell Dev Biol Anim       Date:  2007-01       Impact factor: 2.416

10.  The Centre for Modeling Human Disease Gene Trap resource.

Authors:  Christine To; Trevor Epp; Tammy Reid; Qing Lan; Mei Yu; Carol Y J Li; Minako Ohishi; Paula Hant; Nora Tsao; Guillermo Casallo; Janet Rossant; Lucy R Osborne; William L Stanford
Journal:  Nucleic Acids Res       Date:  2004-01-01       Impact factor: 16.971
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