Literature DB >> 25987788

Diagnosis and surgical treatment of esophageal gastrointestinal stromal tumors.

Fang-Biao Zhang1, Hong-Can Shi1, Yu-Sheng Shu1, Wei-Ping Shi1, Shi-Chun Lu1, Xiang-Yan Zhang1, Shao-Song Tu1.   

Abstract

AIM: To retrospectively evaluate our experience with the diagnosis and surgical resection of esophageal gastrointestinal stromal tumors (GISTs).
METHODS: Between January 2003 and August 2014, five esophageal GIST cases were admitted to our hospital. In this study, the hospital records, surgery outcomes, tumor recurrence and survival of these patients were retrospectively reviewed.
RESULTS: The median age of the patients was 45.6 years (range: 12-62 years). Three patients presented with dysphagia, and one patient presented with chest discomfort. The remaining patient was asymptomatic. Four patients were diagnosed with esophageal GISTs by a preoperative endoscopic biopsy. Three patients underwent esophagectomy, and two patients underwent video-assisted thoracoscopic surgery. The mean operating time was 116 min (range: 95-148 min), and the mean blood loss was 176 mL (range: 30-300 mL). All tumors were completely resected. The mean length of postoperative hospital stay was 8.4 d (range: 6-12 d). All patients recovered and were discharged successfully. The median postoperative follow-up duration was 48 mo (range: 29-72 mo). One patient was diagnosed with recurrence, one patient was lost to follow-up, and three patients were asymptomatic and are currently being managed with close radiologic and clinical follow-up.
CONCLUSION: Surgery is the standard, effective and successful treatment for esophageal GISTs. Long-term follow-up is required to monitor recurrence and metastasis.

Entities:  

Keywords:  Esophagus; Gastrointestinal stromal tumors; Recurrence

Mesh:

Year:  2015        PMID: 25987788      PMCID: PMC4427687          DOI: 10.3748/wjg.v21.i18.5630

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  31 in total

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3.  Multiple primary gastrointestinal stromal tumors presenting in jejunum and ileum.

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7.  Gastric stromal tumors. Reappraisal of histogenesis.

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10.  Clinical, pathologic, and immunohistochemical characteristics of gastrointestinal stromal tumors of the colon and rectum: implications for surgical management and adjuvant therapies.

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  6 in total

Review 1.  Gastrointestinal stromal tumor of the esophagus: current issues of diagnosis, surgery and drug therapy.

Authors:  Jun Hihara; Hidenori Mukaida; Naoki Hirabayashi
Journal:  Transl Gastroenterol Hepatol       Date:  2018-01-22

2.  Robotic-assisted surgery for esophageal submucosal tumors: a single-center case series.

Authors:  Caterina Froiio; Felix Berlth; Giovanni Capovilla; Evangelos Tagkalos; Edin Hadzijusufovic; Carolina Mann; Hauke Lang; Peter Philipp Grimminger
Journal:  Updates Surg       Date:  2022-02-11

3.  Use of endoloop in video-assisted thoracoscopic enucleation of a very rare esophageal tumor.

Authors:  Yahya Alwatari; Wayne Tse; Kasia Trebska-McGowan; Rachit D Shah
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4.  Optimal management of GIST tumors located near the gastroesophageal junction: Case report and review of the literature.

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Review 5.  Gastrointestinal Stromal Tumors of the Small Intestine: Progress in Diagnosis and Treatment Research.

Authors:  Fangxing Peng; Yao Liu
Journal:  Cancer Manag Res       Date:  2020-05-25       Impact factor: 3.989

6.  Clinicopathologic Features and Clinical Outcomes of Esophageal Gastrointestinal Stromal Tumor: Evaluation of a Pooled Case Series.

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  6 in total

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