Clara R Medici1, Claus H Vestergaard2, Peter Hjorth2, Mette V Hansen2, Jan W D Shanmuganathan2, Anne G Viuff3, Povl Munk-Jørgensen4. 1. Department of Organic Psychiatric Disorders and Emergency Ward, Aarhus University Hospital, Risskov, Denmark clara.reece.medici@post.au.dk. 2. Department of Organic Psychiatric Disorders and Emergency Ward, Aarhus University Hospital, Risskov, Denmark. 3. Regional Psychiatric Services West, Herning, Denmark. 4. Aarhus University Hospital, Risskov, Denmark.
Abstract
BACKGROUND: Patients with schizophrenia experience low quality of life (QOL). AIMS: To examine QOL in these patients and the relation between QOL and illness duration, adjusted daily doses (ADDs) of antipsychotics, body mass index (BMI), waist circumference and smoking. METHODS: In this naturalistic, cross-sectional study, 82 patients were interviewed about smoking habits. Patients completed a QOL questionnaire (World Health Organization Quality of Life-Bref) consisting of physical, psychological, social and environmental domains and had height, weight and waist circumference measured. The characteristics and QOL were correlated using multiple regression analysis. RESULTS: QOL was significantly lower in the patients than in the general population (p < .01). In first-ever diagnosed patients, QOL was associated with BMI (regression coefficient (RC): physical -0.73, psychological -1.44 and environmental -0.55; all p < .05), ADD (RC: physical 3.71, psychological 4.37 and environmental 2.94; all p < .10) and smoking (RC: physical -0.69; p < .01). In the long-term ill patients, QOL was associated with BMI (RC: physical -1.19 and psychological -1.28; all p < .05) and illness duration (RC: physical 1.38; p < .05). CONCLUSION: Patients experienced low QOL. Lower QOL was associated with high BMI, low ADD and smoking in first-ever diagnosed patients and with high BMI and short illness duration in long-term ill patients.
BACKGROUND:Patients with schizophrenia experience low quality of life (QOL). AIMS: To examine QOL in these patients and the relation between QOL and illness duration, adjusted daily doses (ADDs) of antipsychotics, body mass index (BMI), waist circumference and smoking. METHODS: In this naturalistic, cross-sectional study, 82 patients were interviewed about smoking habits. Patients completed a QOL questionnaire (World Health Organization Quality of Life-Bref) consisting of physical, psychological, social and environmental domains and had height, weight and waist circumference measured. The characteristics and QOL were correlated using multiple regression analysis. RESULTS: QOL was significantly lower in the patients than in the general population (p < .01). In first-ever diagnosed patients, QOL was associated with BMI (regression coefficient (RC): physical -0.73, psychological -1.44 and environmental -0.55; all p < .05), ADD (RC: physical 3.71, psychological 4.37 and environmental 2.94; all p < .10) and smoking (RC: physical -0.69; p < .01). In the long-term ill patients, QOL was associated with BMI (RC: physical -1.19 and psychological -1.28; all p < .05) and illness duration (RC: physical 1.38; p < .05). CONCLUSION:Patients experienced low QOL. Lower QOL was associated with high BMI, low ADD and smoking in first-ever diagnosed patients and with high BMI and short illness duration in long-term ill patients.
Authors: Melissa J Rowthorn; D Rex Billington; Christian U Krägeloh; Jason Landon; Oleg N Medvedev Journal: Qual Life Res Date: 2019-08-10 Impact factor: 4.147
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Authors: Paula Calvo; Joan R Fortuny; Sergio Guzmán; Cristina Macías; Jonathan Bowen; María L García; Olivia Orejas; Ferran Molins; Asta Tvarijonaviciute; José J Cerón; Antoni Bulbena; Jaume Fatjó Journal: Front Psychol Date: 2016-05-06