Literature DB >> 25986998

War and peace? The oncologic and the palliative care perspective on personalized cancer treatment in a patient with advanced cancer.

Eva K Masel1, Sophie Schur, Doris Posch, Dietmar Weixler, Johannes G Meran, Manuela Schmidinger, Herbert H Watzke.   

Abstract

Personalized cancer treatment utilizing targeted therapies in a tailored approach is based on tumor and/or patient-specific molecular profiles. Recent clinical trials continue to look for new potential targets in heavily pretreated patients or rare disease entities. Careful selection of patients who may derive benefit from such therapies constitutes a challenge. This case report presents an experimental personalized cancer treatment in an advanced cancer patient and provides a list of issues for discussion: How can we combine treatment goals and simultaneously meet the individual needs in advanced cancer reconciling both perspectives: oncology and palliative care?

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Year:  2015        PMID: 25986998     DOI: 10.1007/s00508-015-0803-x

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN: 0043-5325            Impact factor:   1.704


  16 in total

1.  An agenda for personalized medicine.

Authors:  Pauline C Ng; Sarah S Murray; Samuel Levy; J Craig Venter
Journal:  Nature       Date:  2009-10-08       Impact factor: 49.962

2.  Unintended consequences of expensive cancer therapeutics—the pursuit of marginal indications and a me-too mentality that stifles innovation and creativity: the John Conley Lecture.

Authors:  Tito Fojo; Sham Mailankody; Andrew Lo
Journal:  JAMA Otolaryngol Head Neck Surg       Date:  2014-12       Impact factor: 6.223

3.  Invasive palliative interventions: when are they worth it and when are they not?

Authors:  Florian Strasser; David Blum; Daniel Bueche
Journal:  Cancer J       Date:  2010 Sep-Oct       Impact factor: 3.360

4.  Extending life or prolonging death: when is enough actually too much?

Authors:  James W Jones; Laurence B McCullough
Journal:  J Vasc Surg       Date:  2014-08       Impact factor: 4.268

5.  American Society of Clinical Oncology perspective: Raising the bar for clinical trials by defining clinically meaningful outcomes.

Authors:  Lee M Ellis; David S Bernstein; Emile E Voest; Jordan D Berlin; Daniel Sargent; Patricia Cortazar; Elizabeth Garrett-Mayer; Roy S Herbst; Rogerio C Lilenbaum; Camelia Sima; Alan P Venook; Mithat Gonen; Richard L Schilsky; Neal J Meropol; Lowell E Schnipper
Journal:  J Clin Oncol       Date:  2014-03-17       Impact factor: 44.544

6.  Clinimetric perspectives.

Authors:  A R Feinstein
Journal:  J Chronic Dis       Date:  1987

7.  The inner life of physicians and care of the seriously ill.

Authors:  D E Meier; A L Back; R S Morrison
Journal:  JAMA       Date:  2001-12-19       Impact factor: 56.272

8.  Patients' expectations about effects of chemotherapy for advanced cancer.

Authors:  Jane C Weeks; Paul J Catalano; Angel Cronin; Matthew D Finkelman; Jennifer W Mack; Nancy L Keating; Deborah Schrag
Journal:  N Engl J Med       Date:  2012-10-25       Impact factor: 91.245

9.  Modified FOLFOX6 chemotherapy in patients with metastatic urachal cancer.

Authors:  Yutaka Yanagihara; Nozomu Tanji; Noriyoshi Miura; Akitomi Shirato; Kenichi Nishimura; Tetsuya Fukumoto; Koji Azuma; Yuki Miyauchi; Tadahiko Kikugawa; Masayoshi Yokoyama
Journal:  Chemotherapy       Date:  2014-06-25       Impact factor: 2.544

10.  American Society of Clinical Oncology provisional clinical opinion: the integration of palliative care into standard oncology care.

Authors:  Thomas J Smith; Sarah Temin; Erin R Alesi; Amy P Abernethy; Tracy A Balboni; Ethan M Basch; Betty R Ferrell; Matt Loscalzo; Diane E Meier; Judith A Paice; Jeffrey M Peppercorn; Mark Somerfield; Ellen Stovall; Jamie H Von Roenn
Journal:  J Clin Oncol       Date:  2012-02-06       Impact factor: 44.544

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