Literature DB >> 25982291

Eye movements as probes of lexico-semantic processing in a patient with primary progressive aphasia.

Mustafa Seckin1, M-Marsel Mesulam1, Alfred W Rademaker1,2, Joel L Voss3, Sandra Weintraub1, Emily J Rogalski1, Robert S Hurley1.   

Abstract

Eye movement trajectories during a verbally cued object search task were used as probes of lexico-semantic associations in an anomic patient with n>an class="Disease">primary progressive aphasia. Visual search was normal on trials where the target object could be named but became lengthy and inefficient on trials where the object failed to be named. The abnormality was most profound if the noun denoting the object could not be recognized. Even trials where the name of the target object was recognized but not retrieved triggered abnormal eye movements, demonstrating that retrieval failures can have underlying associative components despite intact comprehension of the corresponding noun.

Entities:  

Keywords:  anterior temporal lobe; aphasia; eye movements; object naming; single-word comprehension

Mesh:

Year:  2015        PMID: 25982291      PMCID: PMC4651860          DOI: 10.1080/13554794.2015.1045523

Source DB:  PubMed          Journal:  Neurocase        ISSN: 1355-4794            Impact factor:   0.881


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3.  Taxonomic Interference Associated with Phonemic Paraphasias in Agrammatic Primary Progressive Aphasia.

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