INTRODUCTION: Primary melanocytic lesions of the central nervous system originate from leptomeningeal melanocytes, with a spectrum ranging from well-differentiated benign meningeal melanocytomas to malignant melanomas. Atypical melanocytomas are borderline tumors, which have clinical and pathological characteristics between benign melanocytomas and malignant melanomas. Melanocytomas are rare in children and infrequently arise from the cavernous sinus. Approximately five patients with such an origin site have been reported. MATERIALS AND METHODS: We report a 15-year-old girl with an atypical melanocytoma arising from the cavernous sinus. She underwent partial resection of the tumor and postoperative gamma knife surgery (GKS). She is stable 39 months after surgery. CONCLUSION: We discuss the first pediatric case with an intracranial atypical melanocytoma arising from the cavernous sinus.
INTRODUCTION:Primary melanocytic lesions of the central nervous system originate from leptomeningeal melanocytes, with a spectrum ranging from well-differentiated benign meningeal melanocytomas to malignant melanomas. Atypical melanocytomas are borderline tumors, which have clinical and pathological characteristics between benign melanocytomas and malignant melanomas. Melanocytomas are rare in children and infrequently arise from the cavernous sinus. Approximately five patients with such an origin site have been reported. MATERIALS AND METHODS: We report a 15-year-old girl with an atypical melanocytoma arising from the cavernous sinus. She underwent partial resection of the tumor and postoperative gamma knife surgery (GKS). She is stable 39 months after surgery. CONCLUSION: We discuss the first pediatric case with an intracranial atypical melanocytoma arising from the cavernous sinus.
Authors: Marta Navas; José M Pascual; Javier Fraga; Manuel Pedrosa; Sophia Shakur; Rodrigo Carrasco; Pedro Martínez; Rafael Manzanares; Rafael García de Sola Journal: J Neurooncol Date: 2009-05-18 Impact factor: 4.130