Mehmet Ata Cebe1, Fatma Cebe2, Mehmet Fatih Cengiz3, Ali Rıza Cetin4, Osman Fatih Arpag5, Bora Ozturk6. 1. Abant Izzet Baysal University, Faculty of Dentistry, Department of Restorative Dentistry, Bolu, Turkey. Electronic address: atacebe014@hotmail.com. 2. Abant Izzet Baysal University, Faculty of Dentistry, Department of Restorative Dentistry, Bolu, Turkey. Electronic address: fkahveci61@hotmail.com. 3. Akdeniz University, Food Safety and Agricultural Research Center, Antalya, Turkey. Electronic address: fcengiz@akdeniz.edu.tr. 4. Selcuk University, Faculty of Dentistry, Department of Restorative Dentistry, Konya, Turkey. Electronic address: alirizacetin@selcuk.edu.tr. 5. Mustafa Kemal University, Faculty of Dentistry, Department of Periodontology, Hatay, Turkey. Electronic address: ofarpag@hotmail.com. 6. Selcuk University, Faculty of Dentistry, Department of Restorative Dentistry, Konya, Turkey. Electronic address: bozturk75@hotmail.com.
Abstract
OBJECTIVE: The purpose of this study was to evaluate the elution of Bis-GMA, TEGDMA, HEMA, and Bis-EMA monomers from six bulk fill composite resins over four different time periods, using HPLC. METHODS: Six different composite resin materials were used in the present study: Tetric Evo Ceram Bulk Fill (Ivoclar Vivadent, Amherst, NY), X-tra Fill (VOCO, Cuxhaven, Germany), Sonic Fill (Kerr, Orange, CA, USA), Filtek Bulk Fill (3M ESPE Dental Product, St. Paul, MN), SDR (Dentsply, Konstanz, Germany), EQUIA (GC America INC, Alsip, IL). The samples (4mm thickness, 5mm diameter) were prepared and polymerized for 20s with a light emitted diode unit. After fabrication, each sample was immediately immersed in 75wt% ethanol/water solution used as extraction fluid and stored in the amber colored bottles at room temperature. Ethanol/water samples were taken (0.5mL) at predefined time intervals:10m (T1), 1h (T2), 24h (T3) and 30 days (T4). These samples were analyzed by HPLC. The obtained data were analyzed with one-way ANOVA and Tukey HSD at significance level of p<0.05. RESULTS: Amount of eluted Bis-EMA and Bis-GMA from Tetric Evo Ceram Bulk Fill and amount of eluted TEGDMA and HEMA from X-tra Fill higher than others composites (p<0.05). SIGNIFICANCE: Residual monomers were eluted from bulk fill composite resins in all time periods and the amount of eluted monomers was increased with time.
OBJECTIVE: The purpose of this study was to evaluate the elution of Bis-GMA, TEGDMA, HEMA, and Bis-EMA monomers from six bulk fill composite resins over four different time periods, using HPLC. METHODS: Six different composite resin materials were used in the present study: Tetric Evo Ceram Bulk Fill (Ivoclar Vivadent, Amherst, NY), X-tra Fill (VOCO, Cuxhaven, Germany), Sonic Fill (Kerr, Orange, CA, USA), Filtek Bulk Fill (3M ESPE Dental Product, St. Paul, MN), SDR (Dentsply, Konstanz, Germany), EQUIA (GC America INC, Alsip, IL). The samples (4mm thickness, 5mm diameter) were prepared and polymerized for 20s with a light emitted diode unit. After fabrication, each sample was immediately immersed in 75wt% ethanol/water solution used as extraction fluid and stored in the amber colored bottles at room temperature. Ethanol/water samples were taken (0.5mL) at predefined time intervals:10m (T1), 1h (T2), 24h (T3) and 30 days (T4). These samples were analyzed by HPLC. The obtained data were analyzed with one-way ANOVA and Tukey HSD at significance level of p<0.05. RESULTS: Amount of eluted Bis-EMA and Bis-GMA from Tetric Evo Ceram Bulk Fill and amount of eluted TEGDMA and HEMA from X-tra Fill higher than others composites (p<0.05). SIGNIFICANCE: Residual monomers were eluted from bulk fill composite resins in all time periods and the amount of eluted monomers was increased with time.
Authors: Edina Lempel; Zsuzsanna Czibulya; Bálint Kovács; József Szalma; Ákos Tóth; Sándor Kunsági-Máté; Zoltán Varga; Katalin Böddi Journal: Int J Mol Sci Date: 2016-05-20 Impact factor: 5.923