Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The C57BL/6J Niemann-Pick C1 mouse model with decreased gene dosage is susceptible to increased weight gain when fed a high-fat diet: Confirmation of a gene-diet interaction.

Literature DB >> 25979674

The C57BL/6J Niemann-Pick C1 mouse model with decreased gene dosage is susceptible to increased weight gain when fed a high-fat diet: Confirmation of a gene-diet interaction.

David Jelinek¹, Joseph J Castillo¹, Randall A Heidenreich², William S Garver³.

Abstract

Entities: Chemical Disease Gene Mutation Species

Keywords: Gene-diet interaction; Impaired glucose tolerance; Mouse model; Niemann–Pick C1; Weight gain

Mesh：

Substances：

Year: 2015 PMID： 25979674 PMCID： PMC4483511 DOI： 10.1016/j.gene.2015.05.025

Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688

× No keyword cloud information.

16 in total

1. Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population.

Authors: S Robiou-du-Pont; A Bonnefond; L Yengo; E Vaillant; S Lobbens; E Durand; J Weill; O Lantieri; B Balkau; G Charpentier; M Marre; P Froguel; D Meyre
Journal: Int J Obes (Lond) Date: 2012-10-23 Impact factor: 5.095

2. Type C Niemann-Pick disease. A parallel loss of regulatory responses in both the uptake and esterification of low density lipoprotein-derived cholesterol in cultured fibroblasts.

Authors: P G Pentchev; H S Kruth; M E Comly; J D Butler; M T Vanier; D A Wenger; S Patel
Journal: J Biol Chem Date: 1986-12-15 Impact factor: 5.157

3. The C57BL/6J Niemann-Pick C1 mouse model with decreased gene dosage has impaired glucose tolerance independent of body weight.

Authors: David Jelinek; Joseph J Castillo; William S Garver
Journal: Gene Date: 2013-06-11 Impact factor: 3.688

4. Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations.

Authors: David Meyre; Jérôme Delplanque; Jean-Claude Chèvre; Cécile Lecoeur; Stéphane Lobbens; Sophie Gallina; Emmanuelle Durand; Vincent Vatin; Franck Degraeve; Christine Proença; Stefan Gaget; Antje Körner; Peter Kovacs; Wieland Kiess; Jean Tichet; Michel Marre; Anna-Liisa Hartikainen; Fritz Horber; Natascha Potoczna; Serge Hercberg; Claire Levy-Marchal; François Pattou; Barbara Heude; Maithé Tauber; Mark I McCarthy; Alexandra I F Blakemore; Alexandre Montpetit; Constantin Polychronakos; Jacques Weill; Lachlan J M Coin; Julian Asher; Paul Elliott; Marjo-Riitta Järvelin; Sophie Visvikis-Siest; Beverley Balkau; Rob Sladek; David Balding; Andrew Walley; Christian Dina; Philippe Froguel
Journal: Nat Genet Date: 2009-01-18 Impact factor: 38.330

5. The role of decreased levels of Niemann-Pick C1 intracellular cholesterol transport on obesity is reversed in the C57BL/6J, metabolic syndrome mouse strain: a metabolic or an inflammatory effect?

Authors: Ivan Borbon; Erin Campbell; Wangjing Ke; Robert P Erickson
Journal: J Appl Genet Date: 2012-05-15 Impact factor: 3.240

6. Common body mass index-associated variants confer risk of extreme obesity.

Authors: Chris Cotsapas; Elizabeth K Speliotes; Ida J Hatoum; Danielle M Greenawalt; Radu Dobrin; Pek Y Lum; Christine Suver; Eugene Chudin; Daniel Kemp; Marc Reitman; Benjamin F Voight; Benjamin M Neale; Eric E Schadt; Joel N Hirschhorn; Lee M Kaplan; Mark J Daly
Journal: Hum Mol Genet Date: 2009-06-24 Impact factor: 6.150

7. Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples.

Authors: M den Hoed; J Luan; C Langenberg; C Cooper; A A Sayer; K Jameson; M Kumari; M Kivimaki; A D Hingorani; A Grøntved; K-T Khaw; U Ekelund; N J Wareham; R J F Loos
Journal: Int J Obes (Lond) Date: 2012-03-20 Impact factor: 5.095

8. Studies of metabolic phenotypic correlates of 15 obesity associated gene variants.

Authors: Camilla Helene Sandholt; Marie Aare Vestmar; Dorthe Sadowa Bille; Anders Borglykke; Katrine Almind; Lars Hansen; Annelli Sandbæk; Torsten Lauritzen; Daniel Witte; Torben Jørgensen; Oluf Pedersen; Torben Hansen
Journal: PLoS One Date: 2011-09-02 Impact factor: 3.240

9. The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts.

Authors: L Liscum; R M Ruggiero; J R Faust
Journal: J Cell Biol Date: 1989-05 Impact factor: 10.539

10. Mammalian NPC1 genes may undergo positive selection and human polymorphisms associate with type 2 diabetes.

Authors: Nasser M Al-Daghri; Rachele Cagliani; Diego Forni; Majed S Alokail; Uberto Pozzoli; Khalid M Alkharfy; Shaun Sabico; Mario Clerici; Manuela Sironi
Journal: BMC Med Date: 2012-11-15 Impact factor: 8.775

6 in total

Review 1. The Extending Spectrum of NPC1-Related Human Disorders: From Niemann-Pick C1 Disease to Obesity.

Authors: Amel Lamri; Marie Pigeyre; William S Garver; David Meyre
Journal: Endocr Rev Date: 2018-04-01 Impact factor: 19.871

2. The Niemann-Pick C1 gene interacts with a high-fat diet to promote weight gain through differential regulation of central energy metabolism pathways.

Authors: Joseph J Castillo; David Jelinek; Hao Wei; Nicholas P Gannon; Roger A Vaughan; L John Horwood; F John Meaney; Randi Garcia-Smith; Kristina A Trujillo; Randall A Heidenreich; David Meyre; Robert A Orlando; Renee C LeBoeuf; William S Garver
Journal: Am J Physiol Endocrinol Metab Date: 2017-05-09 Impact factor: 4.310

6. Signatures of natural selection and ethnic-specific prevalence of NPC1 pathogenic mutations contributing to obesity and Niemann-Pick disease type C1.

Authors: Andreea Chiorean; William S Garver; David Meyre
Journal: Sci Rep Date: 2020-11-02 Impact factor: 4.379