BACKGROUND/AIM: Vitamin D (vitD) levels are positively associated with bone health and seasonality affects serum vit D. The aim of the study was to investigate the degree of seasonal variation on 25-hydroxyvitamin D (25(OH)D) serum levels in a population-based cohort of post-menopausal women with osteoporosis. PATIENTS AND METHODS: Serum levels of 25(OH)D were assessed in 596 patients (mean age=65.3 years; standard deviation (SD)=9.4) in different time points over a period of 2.5 years. RESULTS: The minimum 25(OH)D serum levels were observed in March (13.4±9.5 ng/ml) and the maximum levels in August, September and October (29.1±16.1, 28.9±12 and 28.4±8.9 ng/ml, respectively). The prevalence of vitD deficiency, insufficiency and sufficiency in March was 76.5, 15.7 and 7.8%, respectively. On the contrary, the highest prevalence of vitD sufficiency was observed in August, September and October (38.1%, 45.3% and 46.5%, respectively). CONCLUSION: Seasonal variations should be considered when measuring for 25(OH)D serum levels and treating vitD deficiency.
BACKGROUND/AIM: Vitamin D (vitD) levels are positively associated with bone health and seasonality affects serum vit D. The aim of the study was to investigate the degree of seasonal variation on 25-hydroxyvitamin D (25(OH)D) serum levels in a population-based cohort of post-menopausal women with osteoporosis. PATIENTS AND METHODS: Serum levels of 25(OH)D were assessed in 596 patients (mean age=65.3 years; standard deviation (SD)=9.4) in different time points over a period of 2.5 years. RESULTS: The minimum 25(OH)D serum levels were observed in March (13.4±9.5 ng/ml) and the maximum levels in August, September and October (29.1±16.1, 28.9±12 and 28.4±8.9 ng/ml, respectively). The prevalence of vitD deficiency, insufficiency and sufficiency in March was 76.5, 15.7 and 7.8%, respectively. On the contrary, the highest prevalence of vitD sufficiency was observed in August, September and October (38.1%, 45.3% and 46.5%, respectively). CONCLUSION: Seasonal variations should be considered when measuring for 25(OH)D serum levels and treating vitD deficiency.
Authors: Lamprini Β Kontopoulou; Anna Challa; Maria Vaiou; Amalia I Moula; Ioanna V Papathanasiou; Georgios Marakis; Georgios E Karpetas; Evangelos C Fradelos; Dimitrios Papagiannis; Foteini Malli; Christos G Mastorodimos; Konstantinos I Gourgoulianis; Anargyros N Moulas Journal: Adv Exp Med Biol Date: 2021 Impact factor: 2.622
Authors: Sofia Cardoso; Alejandro Santos; Rita S Guerra; Ana S Sousa; Patrícia Padrão; Pedro Moreira; Cláudia Afonso; Teresa F Amaral; Nuno Borges Journal: BMC Geriatr Date: 2017-10-31 Impact factor: 3.921
Authors: Krystian Wochna; Alicja Nowak; Anna Huta-Osiecka; Katarzyna Sobczak; Zbigniew Kasprzak; Piotr Leszczyński Journal: Int J Environ Res Public Health Date: 2019-07-13 Impact factor: 3.390