Literature DB >> 25973942

Synthesis and immunological study of α-2,9-oligosialic acid conjugates as anti-group C meningitis vaccines.

Guochao Liao1, Zhifang Zhou, Zhongwu Guo.   

Abstract

α-2,9-Di-, tri-, tetra-, and pentasialic acids were prepared and conjugated with a carrier protein. The resultant glycoconjugates elicited robust T cell-mediated immunity in mice. α-2,9-Trisialic acid was identified as a promising antigen for developing glycoconjugate vaccines against group C Neisseria meningitidis.

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Year:  2015        PMID： 25973942      PMCID： PMC4526240          DOI： 10.1039/c5cc01794g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  46 in total

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Journal:  Angew Chem Int Ed Engl       Date:  2011-08-29       Impact factor: 15.336

2.  Divergent immunoglobulin g subclass activity through selective Fc receptor binding.

Authors:  Falk Nimmerjahn; Jeffrey V Ravetch
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Review 3.  Conquering the meningococcus.

Authors:  David S Stephens
Journal:  FEMS Microbiol Rev       Date:  2007-01       Impact factor: 16.408

4.  Molecular epidemiology of neisseria meningitidis isolated in the African Meningitis Belt between 1988 and 2003 shows dominance of sequence type 5 (ST-5) and ST-11 complexes.

Authors:  Pierre Nicolas; Gunnstein Norheim; Eric Garnotel; Saacou Djibo; Dominique A Caugant
Journal:  J Clin Microbiol       Date:  2005-10       Impact factor: 5.948

5.  Stereoselective synthesis of oligo-alpha-(2,8)-sialic acids.

Authors:  Hiroshi Tanaka; Yuji Nishiura; Takashi Takahashi
Journal:  J Am Chem Soc       Date:  2006-06-07       Impact factor: 15.419

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7.  Synthesis and use of glycosyl phosphates as glycosyl donors.

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Journal:  Org Lett       Date:  1999-07-29       Impact factor: 6.005

Review 8.  Vaccine prevention of meningococcal disease, coming soon?

Authors:  S L Morley; A J Pollard
Journal:  Vaccine       Date:  2001-12-12       Impact factor: 3.641

9.  Prevalence of de-O-acetylated serogroup C meningococci before the introduction of meningococcal serogroup C conjugate vaccines in the United Kingdom.

Authors:  R Borrow; E Longworth; S J Gray; E B Kaczmarski
Journal:  FEMS Immunol Med Microbiol       Date:  2000-07

10.  Efficient synthesis of an alpha(2,9) trisialic acid by one-pot glycosylation and polymer-assisted deprotection.

Authors:  Hiroshi Tanaka; Yusuke Tateno; Yuji Nishiura; Takashi Takahashi
Journal:  Org Lett       Date:  2008-12-18       Impact factor: 6.005
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  13 in total

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3.  Facile Synthesis of Sugar Lactols via Bromine-Mediated Oxidation of Thioglycosides.

Authors:  Shuai Meng; Bishwa Raj Bhetuwal; Padam P Acharya; Jianglong Zhu
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4.  6-O-Branched Oligo-β-glucan-Based Antifungal Glycoconjugate Vaccines.

Authors:  Guochao Liao; Zhifang Zhou; Jun Liao; Luning Zu; Qiuye Wu; Zhongwu Guo
Journal:  ACS Infect Dis       Date:  2015-12-30       Impact factor: 5.084

5.  Fully Synthetic Self-Adjuvanting α-2,9-Oligosialic Acid Based Conjugate Vaccines against Group C Meningitis.

Authors:  Guochao Liao; Zhifang Zhou; Sharad Suryawanshi; Mohabul A Mondal; Zhongwu Guo
Journal:  ACS Cent Sci       Date:  2016-04-04       Impact factor: 14.553

Review 6.  Meningococcal Vaccines: Current Status and Emerging Strategies.

Authors:  Pumtiwitt C McCarthy; Abeer Sharyan; Laleh Sheikhi Moghaddam
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7.  Novel carbohydrate modified berberine derivatives: synthesis and in vitro anti-diabetic investigation.

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Review 8.  Factors contributing to the immunogenicity of meningococcal conjugate vaccines.

Authors:  Michael Bröker; Francesco Berti; Paolo Costantino
Journal:  Hum Vaccin Immunother       Date:  2016-03-02       Impact factor: 3.452

9.  Synthesis and Evaluation of GM2-Monophosphoryl Lipid A Conjugate as a Fully Synthetic Self-Adjuvant Cancer Vaccine.

Authors:  Zhifang Zhou; Satadru S Mandal; Guochao Liao; Jiatong Guo; Zhongwu Guo
Journal:  Sci Rep       Date:  2017-09-12       Impact factor: 4.379

Review 10.  Recent Advances in the Synthesis of Glycoconjugates for Vaccine Development.

Authors:  Cinzia Colombo; Olimpia Pitirollo; Luigi Lay
Journal:  Molecules       Date:  2018-07-13       Impact factor: 4.411
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