Aykut Soyder1, Füsun Taşkin2, Serdar Ozbas3. 1. Department of General Surgery, Adnan Menderes University Faculty of Medicine, Aydin, Turkey. 2. Department of Radiology, Adnan Menderes University Faculty of Medicine, Aydin, Turkey. 3. Guven Hospital, Ankara, Turkey.
Abstract
BACKGROUND: The objectives of this study were to determine the frequency of imaging-histological discordance and to compare the frequency of carcinoma between discordant lesions at ultrasound (US)-guided core needle biopsy. MATERIALS AND METHODS: From November 2009 to June 2012, we performed US-guided 14-gauge core needle biopsies on 989 breast lesions in 961 women. We reviewed 58 (5.8%) cases that had imaging-histological discordance after percutaneous breast biopsy and underwent subsequent excisional biopsy. The clinical, radiological, and histological findings were reviewed for those 58 cases. RESULTS: Among the 58 cases, subsequent excisions revealed 16 (27.5%) malignancies, which were categorized as 9 (15.5%) invasive ductal carcinomas, 4 (6.9%) malignant phyllodes tumors, and 3 (5.1%) ductal carcinomas in situ. CONCLUSION: The malignancy rate of 27.5% suggests that surgical excision should be performed in those cases presenting with imaging-histological discordance after US-guided core biopsy. Careful correlation of clinical, radiological, and histological results as well as appropriate follow-up are essential. We have submitted a short version of this work as a poster presentation during the 2012 European Society of Surgery (ESS) Congress in Istanbul/Turkey.
BACKGROUND: The objectives of this study were to determine the frequency of imaging-histological discordance and to compare the frequency of carcinoma between discordant lesions at ultrasound (US)-guided core needle biopsy. MATERIALS AND METHODS: From November 2009 to June 2012, we performed US-guided 14-gauge core needle biopsies on 989 breast lesions in 961 women. We reviewed 58 (5.8%) cases that had imaging-histological discordance after percutaneous breast biopsy and underwent subsequent excisional biopsy. The clinical, radiological, and histological findings were reviewed for those 58 cases. RESULTS: Among the 58 cases, subsequent excisions revealed 16 (27.5%) malignancies, which were categorized as 9 (15.5%) invasive ductal carcinomas, 4 (6.9%) malignant phyllodes tumors, and 3 (5.1%) ductal carcinomas in situ. CONCLUSION: The malignancy rate of 27.5% suggests that surgical excision should be performed in those cases presenting with imaging-histological discordance after US-guided core biopsy. Careful correlation of clinical, radiological, and histological results as well as appropriate follow-up are essential. We have submitted a short version of this work as a poster presentation during the 2012 European Society of Surgery (ESS) Congress in Istanbul/Turkey.
Entities:
Keywords:
Breast cancer; Core biopsy; Imaging-histological discordance
Authors: J E Meyer; D N Smith; S C Lester; P J DiPiro; C M Denison; S C Harvey; R L Christian; A Richardson; W D Ko Journal: Radiology Date: 1998-03 Impact factor: 11.105