Literature DB >> 25954672

Unusual Presentation of a Primary Ewing's Sarcoma of the Spine with Paraplegia: A Case Report.

Karthik Kailash Kannan1, Rajkumar Jayachandran Sundarapandian2, Vignesh Jayabalan Surulivel3.   

Abstract

Ewing's sarcoma is a primary malignancy of the bone affecting individuals in the second decade of life. Primary sarcomas of the spine are rare and the occurrence of Primary Ewing's sarcoma in the spine is very rare. Ewing's sarcoma occurring in the spine is divided into two types, Ewing's sarcoma of sacral spine which are very aggressive with poor prognosis and Ewing's sarcoma of the non sacral spine which is an extremely rare occurrence. Patient may present with neurological deficit when the tumour extends into the spinal canal causing spinal cord compression. Magnetic resonance imaging (MRI) is very sensitive in diagnosing the tumour and defining the extent of the tumour. Here we report an 18-year-old boy who presented with back pain and complete paraplegia of two months duration. The MRI gave a differential diagnosis of infective pathology due to the fluid collection in the paraspinal region, followed by primary malignancy as the second diagnosis. Patient underwent posterior spinal decompression and stabilization, and intaoperatively there was significant collection of pus whose culture showed no growth. The histopathology and immunohistochemistry studies confirmed the diagnosis of Ewing's sarcoma and patient was started on combination chemotherapy and radiotherapy.

Entities:  

Keywords:  Paraspinal; Primary malignancy of spine; Spinal cord compression

Year:  2015        PMID: 25954672      PMCID: PMC4413122          DOI: 10.7860/JCDR/2015/11647.5663

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  8 in total

Review 1.  Primitive neuroectodermal tumors of the spine: a comprehensive review with illustrative clinical cases.

Authors:  Jason A Ellis; Robert J Rothrock; Gaetan Moise; Paul C McCormick; Kurenai Tanji; Peter Canoll; Michael G Kaiser; Paul C McCormick
Journal:  Neurosurg Focus       Date:  2011-01       Impact factor: 4.047

2.  Primary Ewings sarcoma of the spine: case report.

Authors:  Leandro I Dini; Rodrigo Mendonça; Pasquale Gallo
Journal:  Arq Neuropsiquiatr       Date:  2006-09       Impact factor: 1.420

3.  Changes in incidence and survival of Ewing sarcoma patients over the past 3 decades: Surveillance Epidemiology and End Results data.

Authors:  Natia Esiashvili; Michael Goodman; Robert B Marcus
Journal:  J Pediatr Hematol Oncol       Date:  2008-06       Impact factor: 1.289

4.  Primary Ewing tumor of the vertebrae: clinical characteristics, prognostic factors, and outcome.

Authors:  L Venkateswaran; C Rodriguez-Galindo; T E Merchant; C A Poquette; B N Rao; A S Pappo
Journal:  Med Pediatr Oncol       Date:  2001-07

5.  Pseudohemangioma of the vertebra: an unusual radiographic manifestation of primary Ewing's sarcoma.

Authors:  J A Bemporad; G Sze; J C Chaloupka; C Duncan
Journal:  AJNR Am J Neuroradiol       Date:  1999 Nov-Dec       Impact factor: 3.825

6.  Ewing's sarcoma of the mobile spine.

Authors:  Rex A W Marco; J Brett Gentry; Laurence D Rhines; Valerae O Lewis; J P Wolinski; Norman Jaffe; Ziya L Gokaslan
Journal:  Spine (Phila Pa 1976)       Date:  2005-04-01       Impact factor: 3.468

7.  Ewing sarcoma demonstrates racial disparities in incidence-related and sex-related differences in outcome: an analysis of 1631 cases from the SEER database, 1973-2005.

Authors:  Muhammad U Jawad; Michael C Cheung; Elijah S Min; Michaela M Schneiderbauer; Leonidas G Koniaris; Sean P Scully
Journal:  Cancer       Date:  2009-08-01       Impact factor: 6.860

8.  Nonmetastatic Ewing's Sarcoma of the Lumbar Spine in an Adult Patient.

Authors:  Maurizio Iacoangeli; Mauro Dobran; Alessandro Di Rienzo; Lucia Giovanna Maria di Somma; Lorenzo Alvaro; Elisa Moriconi; Niccolò Nocchi; Maurizio Gladi; Massimo Scerrati
Journal:  Case Rep Oncol Med       Date:  2012-10-24
  8 in total

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