Literature DB >> 25953906

Mating and memory: an educational primer for use with "epigenetic control of learning and memory in Drosophila by Tip60 HAT action".

Rebecca L Schmidt1, Sara L Sheeley2.   

Abstract

An article by Xu et al. in the December 2014 issue of GENETICS can be used to illustrate epigenetic modification of gene expression, reverse genetic manipulation, genetic/epigenetic influence on behavioral studies, and studies using the Drosophila model organism applied to human disease. This Primer provides background information; technical explanations of genetic, biochemical, and behavioral approaches from the study; and an example of an approach for classroom use with discussion questions to aid in student comprehension of the research article.
Copyright © 2015 by the Genetics Society of America.

Entities:  

Keywords:  Drosophila; Tip60; amyloid precursor protein; courtship memory; epigenetic modification; histone acetylation; mushroom body

Mesh:

Substances:

Year:  2015        PMID: 25953906      PMCID: PMC4423364          DOI: 10.1534/genetics.115.176313

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  37 in total

Review 1.  GAL4 system in Drosophila: a fly geneticist's Swiss army knife.

Authors:  Joseph B Duffy
Journal:  Genesis       Date:  2002 Sep-Oct       Impact factor: 2.487

Review 2.  Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design.

Authors:  S C Hodawadekar; R Marmorstein
Journal:  Oncogene       Date:  2007-08-13       Impact factor: 9.867

3.  Basic confocal microscopy.

Authors:  Carolyn L Smith
Journal:  Curr Protoc Neurosci       Date:  2011-07

Review 4.  Learning and memory in Drosophila: behavior, genetics, and neural systems.

Authors:  Lily Kahsai; Troy Zars
Journal:  Int Rev Neurobiol       Date:  2011       Impact factor: 3.230

5.  Crystal structure of the nucleosome core particle at 2.8 A resolution.

Authors:  K Luger; A W Mäder; R K Richmond; D F Sargent; T J Richmond
Journal:  Nature       Date:  1997-09-18       Impact factor: 49.962

6.  Tip60 HAT activity mediates APP induced lethality and apoptotic cell death in the CNS of a Drosophila Alzheimer's disease model.

Authors:  Sheila K Pirooznia; Jessica Sarthi; Ashley A Johnson; Meridith S Toth; Kellie Chiu; Sravanthi Koduri; Felice Elefant
Journal:  PLoS One       Date:  2012-07-26       Impact factor: 3.240

Review 7.  Amyloid precursor protein processing and Alzheimer's disease.

Authors:  Richard J O'Brien; Philip C Wong
Journal:  Annu Rev Neurosci       Date:  2011       Impact factor: 12.449

8.  Targeting specific HATs for neurodegenerative disease treatment: translating basic biology to therapeutic possibilities.

Authors:  Sheila K Pirooznia; Felice Elefant
Journal:  Front Cell Neurosci       Date:  2013-03-28       Impact factor: 5.505

9.  The C.R.E.A.T.E. approach to primary literature shifts undergraduates' self-assessed ability to read and analyze journal articles, attitudes about science, and epistemological beliefs.

Authors:  Sally G Hoskins; David Lopatto; Leslie M Stevens
Journal:  CBE Life Sci Educ       Date:  2011       Impact factor: 3.325

Review 10.  A tale of histone modifications.

Authors:  P A Grant
Journal:  Genome Biol       Date:  2001-04-05       Impact factor: 13.583

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  2 in total

1.  De Novo KAT5 Variants Cause a Syndrome with Recognizable Facial Dysmorphisms, Cerebellar Atrophy, Sleep Disturbance, and Epilepsy.

Authors:  Jonathan Humbert; Smrithi Salian; Periklis Makrythanasis; Gabrielle Lemire; Justine Rousseau; Sophie Ehresmann; Thomas Garcia; Rami Alasiri; Armand Bottani; Sylviane Hanquinet; Erin Beaver; Jennifer Heeley; Ann C M Smith; Seth I Berger; Stylianos E Antonarakis; Xiang-Jiao Yang; Jacques Côté; Philippe M Campeau
Journal:  Am J Hum Genet       Date:  2020-08-20       Impact factor: 11.025

2.  Effect of kaempferol on the transgenic Drosophila model of Parkinson's disease.

Authors:  Falaq Naz; Smita Jyoti; Yasir Hasan Siddique
Journal:  Sci Rep       Date:  2020-08-14       Impact factor: 4.379

  2 in total

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