Literature DB >> 25952785

Molecular pathogenesis of ovarian clear cell carcinoma.

Ioannis Gounaris1, James D Brenton.   

Abstract

Ovarian clear cell carcinoma is a distinct subtype of epithelial ovarian cancer, characterized by an association with endometriosis, glycogen accumulation and resistance to chemotherapy. Key driver events, including ARID1A mutations and HNF1B overexpression, have been recently identified and their functional characterization is ongoing. Additionally, the role of glycogen in promoting the malignant phenotype is coming under scrutiny. Appreciation of the notion that ovarian clear cell carcinoma is essentially an ectopic uterine cancer will hopefully lead to improved animal models of the disease, in turn paving the way for effective treatments.

Entities:  

Keywords:  ARID1A; HNF1B; PIK3CA cell cancer; endometriosis; genetically engineered mouse models; glycogen; ovarian clear

Mesh：

Substances：

Year:  2015        PMID： 25952785     DOI： 10.2217/fon.15.45

Source DB:  PubMed          Journal:  Future Oncol        ISSN： 1479-6694            Impact factor:   3.404


  15 in total

1.  The diagnostic role of PTEN and ARID1A in serous effusions.

Authors:  Ben Davidson; Maurizio Pinamonti; Dolors Cuevas; Arild Holth; Pio Zeppa; Thomas Hager; Jeremias Wohlschlaeger; Martin Tötsch
Journal:  Virchows Arch       Date:  2017-11-24       Impact factor: 4.064

2.  Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

Authors:  Catherine M Phelan; Karoline B Kuchenbaecker; Jonathan P Tyrer; Siddhartha P Kar; Kate Lawrenson; Stacey J Winham; Joe Dennis; Ailith Pirie; Marjorie J Riggan; Ganna Chornokur; Madalene A Earp; Paulo C Lyra; Janet M Lee; Simon Coetzee; Jonathan Beesley; Lesley McGuffog; Penny Soucy; Ed Dicks; Andrew Lee; Daniel Barrowdale; Julie Lecarpentier; Goska Leslie; Cora M Aalfs; Katja K H Aben; Marcia Adams; Julian Adlard; Irene L Andrulis; Hoda Anton-Culver; Natalia Antonenkova; Gerasimos Aravantinos; Norbert Arnold; Banu K Arun; Brita Arver; Jacopo Azzollini; Judith Balmaña; Susana N Banerjee; Laure Barjhoux; Rosa B Barkardottir; Yukie Bean; Matthias W Beckmann; Alicia Beeghly-Fadiel; Javier Benitez; Marina Bermisheva; Marcus Q Bernardini; Michael J Birrer; Line Bjorge; Amanda Black; Kenneth Blankstein; Marinus J Blok; Clara Bodelon; Natalia Bogdanova; Anders Bojesen; Bernardo Bonanni; Åke Borg; Angela R Bradbury; James D Brenton; Carole Brewer; Louise Brinton; Per Broberg; Angela Brooks-Wilson; Fiona Bruinsma; Joan Brunet; Bruno Buecher; Ralf Butzow; Saundra S Buys; Trinidad Caldes; Maria A Caligo; Ian Campbell; Rikki Cannioto; Michael E Carney; Terence Cescon; Salina B Chan; Jenny Chang-Claude; Stephen Chanock; Xiao Qing Chen; Yoke-Eng Chiew; Jocelyne Chiquette; Wendy K Chung; Kathleen B M Claes; Thomas Conner; Linda S Cook; Jackie Cook; Daniel W Cramer; Julie M Cunningham; Aimee A D'Aloisio; Mary B Daly; Francesca Damiola; Sakaeva Dina Damirovna; Agnieszka Dansonka-Mieszkowska; Fanny Dao; Rosemarie Davidson; Anna DeFazio; Capucine Delnatte; Kimberly F Doheny; Orland Diez; Yuan Chun Ding; Jennifer Anne Doherty; Susan M Domchek; Cecilia M Dorfling; Thilo Dörk; Laure Dossus; Mercedes Duran; Matthias Dürst; Bernd Dworniczak; Diana Eccles; Todd Edwards; Ros Eeles; Ursula Eilber; Bent Ejlertsen; Arif B Ekici; Steve Ellis; Mingajeva Elvira; Kevin H Eng; Christoph Engel; D Gareth Evans; Peter A Fasching; Sarah Ferguson; Sandra Fert Ferrer; James M Flanagan; Zachary C Fogarty; Renée T Fortner; Florentia Fostira; William D Foulkes; George Fountzilas; Brooke L Fridley; Tara M Friebel; Eitan Friedman; Debra Frost; Patricia A Ganz; Judy Garber; María J García; Vanesa Garcia-Barberan; Andrea Gehrig; Aleksandra Gentry-Maharaj; Anne-Marie Gerdes; Graham G Giles; Rosalind Glasspool; Gord Glendon; Andrew K Godwin; David E Goldgar; Teodora Goranova; Martin Gore; Mark H Greene; Jacek Gronwald; Stephen Gruber; Eric Hahnen; Christopher A Haiman; Niclas Håkansson; Ute Hamann; Thomas V O Hansen; Patricia A Harrington; Holly R Harris; Jan Hauke; Alexander Hein; Alex Henderson; Michelle A T Hildebrandt; Peter Hillemanns; Shirley Hodgson; Claus K Høgdall; Estrid Høgdall; Frans B L Hogervorst; Helene Holland; Maartje J Hooning; Karen Hosking; Ruea-Yea Huang; Peter J Hulick; Jillian Hung; David J Hunter; David G Huntsman; Tomasz Huzarski; Evgeny N Imyanitov; Claudine Isaacs; Edwin S Iversen; Louise Izatt; Angel Izquierdo; Anna Jakubowska; Paul James; Ramunas Janavicius; Mats Jernetz; Allan Jensen; Uffe Birk Jensen; Esther M John; Sharon Johnatty; Michael E Jones; Päivi Kannisto; Beth Y Karlan; Anthony Karnezis; Karin Kast; Catherine J Kennedy; Elza Khusnutdinova; Lambertus A Kiemeney; Johanna I Kiiski; Sung-Won Kim; Susanne K Kjaer; Martin Köbel; Reidun K Kopperud; Torben A Kruse; Jolanta Kupryjanczyk; Ava Kwong; Yael Laitman; Diether Lambrechts; Nerea Larrañaga; Melissa C Larson; Conxi Lazaro; Nhu D Le; Loic Le Marchand; Jong Won Lee; Shashikant B Lele; Arto Leminen; Dominique Leroux; Jenny Lester; Fabienne Lesueur; Douglas A Levine; Dong Liang; Clemens Liebrich; Jenna Lilyquist; Loren Lipworth; Jolanta Lissowska; Karen H Lu; Jan Lubinński; Craig Luccarini; Lene Lundvall; Phuong L Mai; Gustavo Mendoza-Fandiño; Siranoush Manoukian; Leon F A G Massuger; Taymaa May; Sylvie Mazoyer; Jessica N McAlpine; Valerie McGuire; John R McLaughlin; Iain McNeish; Hanne Meijers-Heijboer; Alfons Meindl; Usha Menon; Arjen R Mensenkamp; Melissa A Merritt; Roger L Milne; Gillian Mitchell; Francesmary Modugno; Joanna Moes-Sosnowska; Melissa Moffitt; Marco Montagna; Kirsten B Moysich; Anna Marie Mulligan; Jacob Musinsky; Katherine L Nathanson; Lotte Nedergaard; Roberta B Ness; Susan L Neuhausen; Heli Nevanlinna; Dieter Niederacher; Robert L Nussbaum; Kunle Odunsi; Edith Olah; Olufunmilayo I Olopade; Håkan Olsson; Curtis Olswold; David M O'Malley; Kai-Ren Ong; N Charlotte Onland-Moret; Nicholas Orr; Sandra Orsulic; Ana Osorio; Domenico Palli; Laura Papi; Tjoung-Won Park-Simon; James Paul; Celeste L Pearce; Inge Søkilde Pedersen; Petra H M Peeters; Bernard Peissel; Ana Peixoto; Tanja Pejovic; Liisa M Pelttari; Jennifer B Permuth; Paolo Peterlongo; Lidia Pezzani; Georg Pfeiler; Kelly-Anne Phillips; Marion Piedmonte; Malcolm C Pike; Anna M Piskorz; Samantha R Poblete; Timea Pocza; Elizabeth M Poole; Bruce Poppe; Mary E Porteous; Fabienne Prieur; Darya Prokofyeva; Elizabeth Pugh; Miquel Angel Pujana; Pascal Pujol; Paolo Radice; Johanna Rantala; Christine Rappaport-Fuerhauser; Gad Rennert; Kerstin Rhiem; Patricia Rice; Andrea Richardson; Mark Robson; Gustavo C Rodriguez; Cristina Rodríguez-Antona; Jane Romm; Matti A Rookus; Mary Anne Rossing; Joseph H Rothstein; Anja Rudolph; Ingo B Runnebaum; Helga B Salvesen; Dale P Sandler; Minouk J Schoemaker; Leigha Senter; V Wendy Setiawan; Gianluca Severi; Priyanka Sharma; Tameka Shelford; Nadeem Siddiqui; Lucy E Side; Weiva Sieh; Christian F Singer; Hagay Sobol; Honglin Song; Melissa C Southey; Amanda B Spurdle; Zsofia Stadler; Doris Steinemann; Dominique Stoppa-Lyonnet; Lara E Sucheston-Campbell; Grzegorz Sukiennicki; Rebecca Sutphen; Christian Sutter; Anthony J Swerdlow; Csilla I Szabo; Lukasz Szafron; Yen Y Tan; Jack A Taylor; Muy-Kheng Tea; Manuel R Teixeira; Soo-Hwang Teo; Kathryn L Terry; Pamela J Thompson; Liv Cecilie Vestrheim Thomsen; Darcy L Thull; Laima Tihomirova; Anna V Tinker; Marc Tischkowitz; Silvia Tognazzo; Amanda Ewart Toland; Alicia Tone; Britton Trabert; Ruth C Travis; Antonia Trichopoulou; Nadine Tung; Shelley S Tworoger; Anne M van Altena; David Van Den Berg; Annemarie H van der Hout; Rob B van der Luijt; Mattias Van Heetvelde; Els Van Nieuwenhuysen; Elizabeth J van Rensburg; Adriaan Vanderstichele; Raymonda Varon-Mateeva; Ana Vega; Digna Velez Edwards; Ignace Vergote; Robert A Vierkant; Joseph Vijai; Athanassios Vratimos; Lisa Walker; Christine Walsh; Dorothea Wand; Shan Wang-Gohrke; Barbara Wappenschmidt; Penelope M Webb; Clarice R Weinberg; Jeffrey N Weitzel; Nicolas Wentzensen; Alice S Whittemore; Juul T Wijnen; Lynne R Wilkens; Alicja Wolk; Michelle Woo; Xifeng Wu; Anna H Wu; Hannah Yang; Drakoulis Yannoukakos; Argyrios Ziogas; Kristin K Zorn; Steven A Narod; Douglas F Easton; Christopher I Amos; Joellen M Schildkraut; Susan J Ramus; Laura Ottini; Marc T Goodman; Sue K Park; Linda E Kelemen; Harvey A Risch; Mads Thomassen; Kenneth Offit; Jacques Simard; Rita Katharina Schmutzler; Dennis Hazelett; Alvaro N Monteiro; Fergus J Couch; Andrew Berchuck; Georgia Chenevix-Trench; Ellen L Goode; Thomas A Sellers; Simon A Gayther; Antonis C Antoniou; Paul D P Pharoah
Journal:  Nat Genet       Date:  2017-03-27       Impact factor: 38.330

3.  Targeting STAT3 by HO3867 induces apoptosis in ovarian clear cell carcinoma.

Authors:  Kristin Bixel; Uksha Saini; Hemant Kumar Bid; John Fowler; Maria Riley; Ross Wanner; Kalpana Deepa Priya Dorayappan; Sneha Rajendran; Ikuo Konishi; Noriomi Matsumura; David E Cohn; Karuppaiyah Selvendiran
Journal:  Int J Cancer       Date:  2017-07-24       Impact factor: 7.396

4.  Whole-genome/exome analysis of circulating tumor DNA and comparison to tumor genomics from patients with heavily pre-treated ovarian cancer: subset analysis of the PERMED-01 trial.

Authors:  Renaud Sabatier; Séverine Garnier; Arnaud Guille; Nadine Carbuccia; Jihane Pakradouni; José Adelaide; Magali Provansal; Maria Cappiello; Frédérique Rousseau; Max Chaffanet; Daniel Birnbaum; Emilie Mamessier; Anthony Gonçalves; François Bertucci
Journal:  Front Oncol       Date:  2022-07-29       Impact factor: 5.738

5.  DNA Methylation Profiles of Ovarian Clear Cell Carcinoma.

Authors:  Kelly L Bolton; Francesmary Modugno; Ellen L Goode; Julie M Cunningham; Stacey J Winham; Chen Wang; Britta Weiglt; Zhuxuan Fu; Sebastian M Armasu; Bryan M McCauley; Alison H Brand; Yoke-Eng Chiew; Esther Elishaev; Charlie Gourley; Catherine J Kennedy; Angela Laslavic; Jenny Lester; Anna Piskorz; Magdalena Sekowska; James D Brenton; Michael Churchman; Anna DeFazio; Ronny Drapkin; Kevin M Elias; David G Huntsman; Beth Y Karlan; Martin Köbel; Jason Konner; Kate Lawrenson; Elli Papaemmanuil
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2021-10-25       Impact factor: 4.090

6.  Ovarian Clear Cell Carcinoma Sub-Typing by ARID1A Expression.

Authors:  Jae Yoon Choi; Hyun Ho Han; Young Tae Kim; Joo Hyun Lee; Baek Gil Kim; Suki Kang; Nam Hoon Cho
Journal:  Yonsei Med J       Date:  2017-01       Impact factor: 2.759

Review 7.  Update on rare epithelial ovarian cancers: based on the Rare Ovarian Tumors Young Investigator Conference.

Authors:  Ji Yon Agnes Jang; Nozomu Yanaihara; Eric Pujade-Lauraine; Yoshiki Mikami; Katsutoshi Oda; Michael Bookman; Jonathan Ledermann; Muneaki Shimada; Takako Kiyokawa; Byoung Gie Kim; Noriomi Matsumura; Tsunehisa Kaku; Takafumi Kuroda; Yoko Nagayoshi; Ayako Kawabata; Yasushi Iida; Jae Weon Kim; Michael Quinn; Aikou Okamoto
Journal:  J Gynecol Oncol       Date:  2017-07       Impact factor: 4.401

8.  Involvement of Chromatin Remodeling Genes and the Rho GTPases RhoB and CDC42 in Ovarian Clear Cell Carcinoma.

Authors:  Nicolai Skovbjerg Arildsen; Jenny-Maria Jönsson; Katarina Bartuma; Anna Ebbesson; Sofia Westbom-Fremer; Anna Måsbäck; Susanne Malander; Mef Nilbert; Ingrid A Hedenfalk
Journal:  Front Oncol       Date:  2017-05-29       Impact factor: 6.244

Review 9.  Current Position of the Molecular Therapeutic Targets for Ovarian Clear Cell Carcinoma: A Literature Review.

Authors:  Tsukuru Amano; Tokuhiro Chano; Fumi Yoshino; Fuminori Kimura; Takashi Murakami
Journal:  Healthcare (Basel)       Date:  2019-07-30

10.  Disruption of Glycogen Utilization Markedly Improves the Efficacy of Carboplatin against Preclinical Models of Clear Cell Ovarian Carcinoma.

Authors:  Tashbib Khan; Yaowu He; Thomas Kryza; Brittney S Harrington; Jennifer H Gunter; Mitchell A Sullivan; Tahleesa Cuda; Rebecca Rogers; Claire M Davies; Amy Broomfield; Madeline Gough; Andy C Wu; Thomas McGann; S John Weroha; Paul Haluska; Josephine M Forbes; Jane E Armes; Sinead C Barry; Jermaine I Coward; Nisha Jagasia; Naven Chetty; Cameron E Snell; Rohan Lourie; Lewis C Perrin; John D Hooper
Journal:  Cancers (Basel)       Date:  2020-04-03       Impact factor: 6.639
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.