Weigang Wang1, Ping Li2, Yishu Wang3, Yuantao Wang1, Zhiyong Ma1, Gang Wang1, Jialin Gao1, Honglan Zhou4. 1. The Second Department of Urology, The First Hospital, Jilin University, 71 Xinmin Street, Changchun 130021, China. 2. Department of Rheumatology and Immunology, China-Japan Union Hospital, Jilin University, Changchun, China. 3. Key Laboratory of Pathobiology, Ministry of Education, School of Basic Medical Sciences, Jilin University, Changchun, China. 4. The Second Department of Urology, The First Hospital, Jilin University, 71 Xinmin Street, Changchun 130021, China. Electronic address: walkerzhouhl@163.com.
Abstract
BACKGROUND: Laparoscopic adrenalectomy (LA) is normally used to treat small-sized (<6 cm) pheochromocytoma (PCC). This study evaluated the effectiveness and safety of LA for treating large (≥6 cm) PCC. METHODS: Fifty-one patients with resectable, large-sized (≥6 cm) PCC were prospectively enrolled for elective LA (n = 23) or open adrenalectomy (n = 28). RESULTS: LA was converted into open adrenalectomy in 2 patients (2/23, 8.7%); LA was associated with relatively longer operative time (P = .033) but less intraoperative bleeding (P < .001), faster resumption of ambulatory status (P < .001), and shorter duration of postoperative hospitalization (P < .001). Frequency of PCC recurrence was similar between the 2 groups (P = 1.000). CONCLUSIONS: LA is a feasible, effective, and safe treatment modality for large-sized (≥6 cm) PCC. LA is associated with minimal invasiveness and faster postoperative recovery.
BACKGROUND: Laparoscopic adrenalectomy (LA) is normally used to treat small-sized (<6 cm) pheochromocytoma (PCC). This study evaluated the effectiveness and safety of LA for treating large (≥6 cm) PCC. METHODS: Fifty-one patients with resectable, large-sized (≥6 cm) PCC were prospectively enrolled for elective LA (n = 23) or open adrenalectomy (n = 28). RESULTS: LA was converted into open adrenalectomy in 2 patients (2/23, 8.7%); LA was associated with relatively longer operative time (P = .033) but less intraoperative bleeding (P < .001), faster resumption of ambulatory status (P < .001), and shorter duration of postoperative hospitalization (P < .001). Frequency of PCC recurrence was similar between the 2 groups (P = 1.000). CONCLUSIONS: LA is a feasible, effective, and safe treatment modality for large-sized (≥6 cm) PCC. LA is associated with minimal invasiveness and faster postoperative recovery.
Authors: Hartmut P H Neumann; Uliana Tsoy; Irina Bancos; Vincent Amodru; Martin K Walz; Amit Tirosh; Ravinder Jeet Kaur; Travis McKenzie; Xiaoping Qi; Tushar Bandgar; Roman Petrov; Marina Y Yukina; Anna Roslyakova; Anouk N A van der Horst-Schrivers; Annika M A Berends; Ana O Hoff; Luciana Audi Castroneves; Alfonso Massimiliano Ferrara; Silvia Rizzati; Caterina Mian; Sarka Dvorakova; Kornelia Hasse-Lazar; Andrey Kvachenyuk; Mariola Peczkowska; Paola Loli; Feyza Erenler; Tobias Krauss; Madson Q Almeida; Longfei Liu; Feizhou Zhu; Mònica Recasens; Nelson Wohllk; Eleonora P M Corssmit; Zulfiya Shafigullina; Jan Calissendorff; Simona Grozinsky-Glasberg; Tada Kunavisarut; Camilla Schalin-Jäntti; Frederic Castinetti; Petr Vlcek; Dmitry Beltsevich; Viacheslav I Egorov; Francesca Schiavi; Thera P Links; Ronald M Lechan; Birke Bausch; William F Young; Charis Eng Journal: JAMA Netw Open Date: 2019-08-02
Authors: Filip Čtvrtlík; Pavel Koranda; Jan Schovánek; Jozef Škarda; Igor Hartmann; Zbyněk Tüdös Journal: Exp Ther Med Date: 2018-02-14 Impact factor: 2.447