Literature DB >> 25944530

Sydoxanthone C and acremolin B produced by deep-sea-derived fungus Aspergillus sp. SCSIO Ind09F01.

Yongqi Tian1,2, Xiaochu Qin3, Xiuping Lin1, Kumaravel Kaliyaperumal1, Xuefeng Zhou1, Juan Liu1, Zhiran Ju1, Zhengchao Tu3, Yonghong Liu1.   

Abstract

A new xanthone named sydoxanthone C (1) and a new alkaloid named acremolin B (2), together with 10 known compounds (3-12) were isolated from a deep-sea-derived fungus Aspergillus sp. SCSIO Ind09F01. The structures of compounds (1-12) were determined by the extensive 1D, 2D-NMR, High resolution mass spectra (HRESIMS) data. Compounds 7, 8, 11 and 12 showed significant selective cytotoxicities against HeLa, DU145 and U937 cell lines. In addition, compounds 7, 8 and 11 also exhibited COX-2 inhibitory activities with the prominent IC50 values of 2.4, 7.1 and 10.6 μM, respectively.

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Year:  2015        PMID： 25944530     DOI： 10.1038/ja.2015.55

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  13 in total

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Authors:  John W Blunt; Brent R Copp; Robert A Keyzers; Murray H G Munro; Michèle R Prinsep
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3.  Diphenyl etheric metabolites from Streptomyces sp. neau50.

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Journal:  J Antibiot (Tokyo)       Date:  2011-04-06       Impact factor: 2.649

Review 4.  Secondary metabolites of fungi from marine habitats.

Authors:  Mostafa E Rateb; Rainer Ebel
Journal:  Nat Prod Rep       Date:  2011-01-12       Impact factor: 13.423

5.  New diphenyl ethers from the insect pathogenic fungus Cordyceps sp. BCC 1861.

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Journal:  Chem Pharm Bull (Tokyo)       Date:  2007-02       Impact factor: 1.645

Review 6.  Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): cyclooxygenase (COX) inhibition and beyond.

Authors:  Praveen Rao; Edward E Knaus
Journal:  J Pharm Pharm Sci       Date:  2008-09-20       Impact factor: 2.327

Review 7.  Calnexin: a membrane-bound chaperone of the endoplasmic reticulum.

Authors:  J J Bergeron; M B Brenner; D Y Thomas; D B Williams
Journal:  Trends Biochem Sci       Date:  1994-03       Impact factor: 13.807

8.  Acremolin from Acremonium strictum is N(2),3-etheno-2'-isopropyl-1-methylguanine, not a 1H-azirine. Synthesis and structural revision.

Authors:  Lawrence A Januar; Tadeusz F Molinski
Journal:  Org Lett       Date:  2013-05-01       Impact factor: 6.005

9.  Cytotoxic polyketides from the deep-sea-derived fungus Engyodontium album DFFSCS021.

Authors:  Qifeng Yao; Jie Wang; Xiaoyong Zhang; Xuhua Nong; Xinya Xu; Shuhua Qi
Journal:  Mar Drugs       Date:  2014-12-09       Impact factor: 5.118

10.  The 2'-Trifluoromethyl Analogue of Indomethacin Is a Potent and Selective COX-2 Inhibitor.

Authors:  Anna L Blobaum; Md Jashim Uddin; Andrew S Felts; Brenda C Crews; Carol A Rouzer; Lawrence J Marnett
Journal:  ACS Med Chem Lett       Date:  2013-03-25       Impact factor: 4.345
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  9 in total

Review 1.  Marine Alkylpurines: A Promising Group of Bioactive Marine Natural Products.

Authors:  Pablo A García; Elena Valles; David Díez; María-Ángeles Castro
Journal:  Mar Drugs       Date:  2018-01-01       Impact factor: 5.118

2.  Asteltoxins with Antiviral Activities from the Marine Sponge-Derived Fungus Aspergillus sp. SCSIO XWS02F40.

Authors:  Yong-Qi Tian; Xiu-Ping Lin; Zhen Wang; Xue-Feng Zhou; Xiao-Chu Qin; Kumaravel Kaliyaperumal; Tian-Yu Zhang; Zheng-Chao Tu; Yonghong Liu
Journal:  Molecules       Date:  2015-12-26       Impact factor: 4.411

3.  Phenol Derivatives From the Sponge-Derived Fungus Didymellaceae sp. SCSIO F46.

Authors:  Yongqi Tian; Xiuping Lin; Xuefeng Zhou; Yonghong Liu
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4.  Screening for Sulfur Compounds by Molybdenum-Catalyzed Oxidation Combined with Liquid Chromatography-Mass Spectrometry.

Authors:  Hirotaka Matsuo; Yu Hanamure; Rei Miyano; Yōko Takahashi; Satoshi Ōmura; Takuji Nakashima
Journal:  Molecules       Date:  2020-01-07       Impact factor: 4.411

Review 5.  Novel Natural Products from Extremophilic Fungi.

Authors:  Xuan Zhang; Shou-Jie Li; Jin-Jie Li; Zi-Zhen Liang; Chang-Qi Zhao
Journal:  Mar Drugs       Date:  2018-06-04       Impact factor: 5.118

6.  Diphenyl Ethers from a Marine-Derived Aspergillus sydowii.

Authors:  Ya-Nan Wang; Yan-Hua Mou; Yu Dong; Yan Wu; Bing-Yu Liu; Jian Bai; Dao-Jiang Yan; Le Zhang; Dan-Qing Feng; Yue-Hu Pei; You-Cai Hu
Journal:  Mar Drugs       Date:  2018-11-16       Impact factor: 5.118

7.  Two New Altenusin/Thiazole Hybrids and a New Benzothiazole Derivative from the Marine Sponge-Derived Fungus Alternaria sp. SCSIOS02F49.

Authors:  Yaping Chen; Ruyan Chen; Jinhuai Xu; Yongqi Tian; Jiangping Xu; Yonghong Liu
Journal:  Molecules       Date:  2018-11-01       Impact factor: 4.411

Review 8.  A Review of Anti-Inflammatory Compounds from Marine Fungi, 2000-2018.

Authors:  Jianzhou Xu; Mengqi Yi; Lijian Ding; Shan He
Journal:  Mar Drugs       Date:  2019-11-09       Impact factor: 5.118

Review 9.  Bioactive Marine Xanthones: A Review.

Authors:  José X Soares; Daniela R P Loureiro; Ana Laura Dias; Salete Reis; Madalena M M Pinto; Carlos M M Afonso
Journal:  Mar Drugs       Date:  2022-01-08       Impact factor: 5.118
  9 in total

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