Lawrence A Januar1, Tadeusz F Molinski. 1. Department of Chemistry and Biochemistry, and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego , 9500 Gilman Drive MC0358, La Jolla, California 92093, United States.
Abstract
The first synthesis of the heterocyclic marine natural product, acremolin, is reported along with the revision of the structure from a 1H-azirine to a substituted N(2),3-ethenoguanine (5-methyl-7-isopropyl-4,5-dihydroimidazo[2,1-b]purine). Additional properties of acremolin are also described including its (1)H-(15)N-HMBC and fluorescence spectra.
The first synthesis of the heterocyclic marine natural product, acremolin, is reported along with the revision of the structure from a n class="Chemical">1H-azirine to a substituted N(2),3-ethenoguanine (5-methyl-7-isopropyl-4,5-dihydroimidazo[2,1-b]purine). Additional properties of acremolin are also described including its (1)H-(15)N-HMBC and fluorescence spectra.
Authors: Alexander F Khlebnikov; Mikhail S Novikov; Viktoriia V Pakalnis; Roman O Iakovenko; Dmitry S Yufit Journal: Beilstein J Org Chem Date: 2014-04-04 Impact factor: 2.883