Christian Geroin1, Nicola Smania2, Federico Schena3, Eleonora Dimitrova4, Elisabetta Verzini5, Federica Bombieri6, Francesca Nardello7, Michele Tinazzi8, Marialuisa Gandolfi9. 1. Neuromotor and Cognitive Rehabilitation Research Center (CRRNC), Department of Neurological and Movement Sciences, University of Verona, P.le L.A. Scuro 10, 37134 Verona, Italy. Electronic address: christian.geroin@univr.it. 2. Neuromotor and Cognitive Rehabilitation Research Center (CRRNC), Department of Neurological and Movement Sciences, University of Verona, P.le L.A. Scuro 10, 37134 Verona, Italy; Neurological Rehabilitation Unit, Azienda Ospedaliera Universitaria Integrata, P.le Scuro 10, 37134 Verona, Italy. Electronic address: nicola.smania@univr.it. 3. School of Sport and Exercise Sciences, Department of Neurological and Movement Sciences, University of Verona, Via Casorati 43, 37137 Verona, Italy. Electronic address: federico.schena@univr.it. 4. Neuromotor and Cognitive Rehabilitation Research Center (CRRNC), Department of Neurological and Movement Sciences, University of Verona, P.le L.A. Scuro 10, 37134 Verona, Italy. Electronic address: eleonora.dimitrova11@gmail.com. 5. School of Specialization in Physical Medicine and Rehabilitation, Department of Neurological and Movement Sciences, University of Verona, Italy. Electronic address: elisabetta.verzini@gmail.com. 6. School of Sport and Exercise Sciences, Department of Neurological and Movement Sciences, University of Verona, Via Casorati 43, 37137 Verona, Italy. Electronic address: federica.bombieri@univr.it. 7. School of Sport and Exercise Sciences, Department of Neurological and Movement Sciences, University of Verona, Via Casorati 43, 37137 Verona, Italy. Electronic address: francesca.nardello@univr.it. 8. Neurology Unit, Movement Disorders Division, Department of Neurological and Movement Sciences, University of Verona, P.le Scuro 10, 37134 Verona, Italy. Electronic address: michele.tinazzi@univr.it. 9. Neuromotor and Cognitive Rehabilitation Research Center (CRRNC), Department of Neurological and Movement Sciences, University of Verona, P.le L.A. Scuro 10, 37134 Verona, Italy. Electronic address: marialuisa.gandolfi@univr.it.
Abstract
INTRODUCTION: An altered sense of verticality, associated with impaired proprioception and somatosensory integration deficits, has been reported in patients with Parkinson's disease (PD) but it has not been characterized in patients with Pisa syndrome (PS). Therefore, we investigated postural control, balance, and gait disturbances in patients with PD and PS, patients with PD but without PS, and aged-matched normal controls. METHODS: This observational cross-sectional study involved patients with PD and PS (n = 10, Hoehn & Yahr score <4), patients with PD but without PS (n = 10), and age-matched healthy controls (n = 10). The primary outcome measure was the velocity of CoP displacement (VEL_MED_AP/ML) assessed by static stabilometry in eyes open (EO) and eyes closed (EC) conditions. The secondary outcomes were other stabilometric parameters, the Sensory Organization Balance Test (SOT), and gait analysis (GA). RESULTS: There were no significant differences in demographic and clinical data and Berg Balance Scale scores between the groups. There was a significant main effect in the VEL_MED_AP/ML between the groups and eye conditions (p = .016). A significant main effect was found in the EO (p = .01) and EC (p = .04) conditions. Post-hoc comparisons showed a significant increase in VEL_CoP in both the EO and EC conditions only in the patients with PD and PS. No significant main effects on SOT and GA were found. CONCLUSION: Patients with PD and PS had more difficulty achieving good postural alignment with gravity and greater velocity of body sway than the other groups. Rehabilitation programs for patients with PD and PS should include spine alignment and dynamic postural training.
INTRODUCTION: An altered sense of verticality, associated with impaired proprioception and somatosensory integration deficits, has been reported in patients with Parkinson's disease (PD) but it has not been characterized in patients with Pisa syndrome (PS). Therefore, we investigated postural control, balance, and gait disturbances in patients with PD and PS, patients with PD but without PS, and aged-matched normal controls. METHODS: This observational cross-sectional study involved patients with PD and PS (n = 10, Hoehn & Yahr score <4), patients with PD but without PS (n = 10), and age-matched healthy controls (n = 10). The primary outcome measure was the velocity of CoP displacement (VEL_MED_AP/ML) assessed by static stabilometry in eyes open (EO) and eyes closed (EC) conditions. The secondary outcomes were other stabilometric parameters, the Sensory Organization Balance Test (SOT), and gait analysis (GA). RESULTS: There were no significant differences in demographic and clinical data and Berg Balance Scale scores between the groups. There was a significant main effect in the VEL_MED_AP/ML between the groups and eye conditions (p = .016). A significant main effect was found in the EO (p = .01) and EC (p = .04) conditions. Post-hoc comparisons showed a significant increase in VEL_CoP in both the EO and EC conditions only in the patients with PD and PS. No significant main effects on SOT and GA were found. CONCLUSION:Patients with PD and PS had more difficulty achieving good postural alignment with gravity and greater velocity of body sway than the other groups. Rehabilitation programs for patients with PD and PS should include spine alignment and dynamic postural training.
Authors: S R Blau; L M Davis; A M Gorney; C S Dohse; K D Williams; J-H Lim; W G Pfitzner; E Laber; G S Sawicki; N J Olby Journal: Vet J Date: 2017-07-20 Impact factor: 2.688
Authors: C Geroin; G Squintani; A Morini; F Donato; Nicola Smania; Maria Giovanna Gandolfi; S Tamburin; Alfonso Fasano; Michele Tinazzi Journal: Funct Neurol Date: 2017 Jul/Sep
Authors: Marialuisa Gandolfi; Christian Geroin; Eleonora Dimitrova; Paolo Boldrini; Andreas Waldner; Silvia Bonadiman; Alessandro Picelli; Sara Regazzo; Elena Stirbu; Daniela Primon; Christian Bosello; Aristide Roberto Gravina; Luca Peron; Monica Trevisan; Alberto Carreño Garcia; Alessia Menel; Laura Bloccari; Nicola Valè; Leopold Saltuari; Michele Tinazzi; Nicola Smania Journal: Biomed Res Int Date: 2017-11-26 Impact factor: 3.411