Literature DB >> 25940198

High seroprevalence of chikungunya virus antibodies among pregnant women living in an urban area in Benin, West Africa.

Anastasia Bacci1, Serena Marchi1, Nadine Fievet1, Achille Massougbodji1, Renè Xavier Perrin1, Jean-Philippe Chippaux1, Vittorio Sambri1, Maria Paola Landini1, Stefania Varani1, Giada Rossini2.   

Abstract

The aim of this study was to investigate the seroprevalence of antichikungunya virus (anti-CHIKV) antibodies in pregnant women living in an urban area of Benin (West Africa). Results were obtained by screening sera collected in 2006 and 2007 with enzyme-linked immunosorbent assay (ELISA) for anti-CHIKV immunoglobulin G (IgG) and IgM. Positive results were confirmed by indirect immunofluorescence test and microneutralization assay. We found that a large proportion (36.1%) of pregnant women living in Cotonou had specific IgG against CHIKV, indicating a high seroprevalence of the infection in urban southern Benin, whereas no active cases of CHIKV infection were detected. © The American Society of Tropical Medicine and Hygiene.

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Year:  2015        PMID： 25940198      PMCID： PMC4458815          DOI： 10.4269/ajtmh.14-0092

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


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