Literature DB >> 25939984

Mechanisms of transfer of bioactive molecules through the cell membrane by electroporation.

Mindaugas S Venslauskas1, Saulius Šatkauskas.   

Abstract

A short review of biophysical mechanisms for electrotransfer of bioactive molecules through the cell membrane by using electroporation is presented. The concept of transient hydrophilic aqueous pores and membrane electroporation mechanisms of single cells and cells in suspension models are analyzed. Alongside the theoretical approach, some peculiarities of drug and gene electrotransfer into cells and applications in clinical trials are discussed.

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Year:  2015        PMID： 25939984     DOI： 10.1007/s00249-015-1025-x

Source DB:  PubMed          Journal:  Eur Biophys J        ISSN： 0175-7571            Impact factor:   1.733


  116 in total

1.  Electroporation and electrophoretic DNA transfer into cells. The effect of DNA interaction with electropores.

Authors:  S I Sukharev; V A Klenchin; S M Serov; L V Chernomordik
Journal:  Biophys J       Date:  1992-11       Impact factor: 4.033

2.  Theoretical and experimental analysis of conductivity, ion diffusion and molecular transport during cell electroporation--relation between short-lived and long-lived pores.

Authors:  Mojca Pavlin; Damijan Miklavcic
Journal:  Bioelectrochemistry       Date:  2008-04-18       Impact factor: 5.373

3.  Efficiency of the delivery of small charged molecules into cells in vitro.

Authors:  M S Venslauskas; S Satkauskas; R Rodaite-Riseviciene
Journal:  Bioelectrochemistry       Date:  2009-10-24       Impact factor: 5.373

4.  In vivo electrically mediated protein and gene transfer in murine melanoma.

Authors:  M P Rols; C Delteil; M Golzio; P Dumond; S Cros; J Teissie
Journal:  Nat Biotechnol       Date:  1998-02       Impact factor: 54.908

5.  Pulse-length dependence of the electrical breakdown in lipid bilayer membranes.

Authors:  R Benz; U Zimmermann
Journal:  Biochim Biophys Acta       Date:  1980-04-24

6.  Electrochemotherapy with cisplatin: the systemic antitumour effectiveness of cisplatin can be potentiated locally by the application of electric pulses in the treatment of malignant melanoma skin metastases.

Authors:  G Sersa; B Stabuc; M Cemazar; D Miklavcic; Z Rudolf
Journal:  Melanoma Res       Date:  2000-08       Impact factor: 3.599

7.  Electroendocytosis: exposure of cells to pulsed low electric fields enhances adsorption and uptake of macromolecules.

Authors:  Yulia Antov; Alexander Barbul; Hila Mantsur; Rafi Korenstein
Journal:  Biophys J       Date:  2004-11-19       Impact factor: 4.033

8.  Bleomycin-mediated electrochemotherapy of basal cell carcinoma.

Authors:  L F Glass; N A Fenske; M Jaroszeski; R Perrott; D T Harvey; D S Reintgen; R Heller
Journal:  J Am Acad Dermatol       Date:  1996-01       Impact factor: 11.527

9.  Electroporation enhances radiation and doxorubicin-induced toxicity in solid tumor in vivo.

Authors:  Pratip Shil; Amit Kumar; Pandit B Vidyasagar; Kaushala P Mishra
Journal:  J Environ Pathol Toxicol Oncol       Date:  2006       Impact factor: 3.567

10.  Metastable pores at the onset of constant-current electroporation.

Authors:  Malgorzata Kotulska; Joanna Basalyga; Maria B Derylo; Przemyslaw Sadowski
Journal:  J Membr Biol       Date:  2010-07-23       Impact factor: 1.843
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  16 in total

1.  Changes in optical properties of electroporated cells as revealed by digital holographic microscopy.

Authors:  Violeta L Calin; Mona Mihailescu; Nicolae Mihale; Alexandra V Baluta; Eugenia Kovacs; Tudor Savopol; Mihaela G Moisescu
Journal:  Biomed Opt Express       Date:  2017-03-16       Impact factor: 3.732

Review 2.  In vitro and ex vivo strategies for intracellular delivery.

Authors:  Martin P Stewart; Armon Sharei; Xiaoyun Ding; Gaurav Sahay; Robert Langer; Klavs F Jensen
Journal:  Nature       Date:  2016-10-13       Impact factor: 49.962

3.  Simulation of the osmosis-based drug encapsulation in erythrocytes.

Authors:  Duobiao Ge; Lili Zou; Chengpan Li; Sen Liu; Shibo Li; Sijie Sun; Weiping Ding
Journal:  Eur Biophys J       Date:  2017-09-20       Impact factor: 1.733

4.  Calcein Release from Cells In Vitro via Reversible and Irreversible Electroporation.

Authors:  Violeta Rajeckaitė; Baltramiejus Jakštys; Arnas Rafanavičius; Martynas Maciulevičius; Milda Jakutavičiūtė; Saulius Šatkauskas
Journal:  J Membr Biol       Date:  2017-11-15       Impact factor: 1.843

5.  Improvement in Electrotransfection of Cells Using Carbon-Based Electrodes.

Authors:  Chun-Chi Chang; Mao Mao; Yang Liu; Mina Wu; Tuan Vo-Dinh; Fan Yuan
Journal:  Cell Mol Bioeng       Date:  2016-06-13       Impact factor: 2.321

6.  Gene delivery in adherent and suspension cells using the combined physical methods.

Authors:  Kimia Kardani; Alireza Milani; Azam Bolhassani
Journal:  Cytotechnology       Date:  2022-02-03       Impact factor: 2.058

7.  Assessing membrane material properties from the response of giant unilamellar vesicles to electric fields.

Authors:  Mina Aleksanyan; Hammad A Faizi; Maria-Anna Kirmpaki; Petia M Vlahovska; Karin A Riske; Rumiana Dimova
Journal:  Adv Phys X       Date:  2022-10-06

Review 8.  Delivery of transcription factors as modulators of cell differentiation.

Authors:  Héctor Rilo-Alvarez; Adriana M Ledo; Anxo Vidal; Marcos Garcia-Fuentes
Journal:  Drug Deliv Transl Res       Date:  2021-02-20       Impact factor: 4.617

9.  Numerical optimization of microfluidic vortex shedding for genome editing T cells with Cas9.

Authors:  Justin A Jarrell; Brandon J Sytsma; Leah H Wilson; Fong L Pan; Katherine H W J Lau; Giles T S Kirby; Adrian A Lievano; Ryan S Pawell
Journal:  Sci Rep       Date:  2021-06-03       Impact factor: 4.379

Review 10.  Microfluidic and Nanofluidic Intracellular Delivery.

Authors:  Jeongsoo Hur; Aram J Chung
Journal:  Adv Sci (Weinh)       Date:  2021-06-06       Impact factor: 16.806
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