Literature DB >> 25935507

Radiation dose for normal organs by helical tomotherapy for lung cancer.

Hsien-Chun Tseng1, Wen-Shan Liu2, Hsiao-Han Tsai3, Hsin-Yi Chu4, Jye-Bin Lin5, Chien-Yi Chen6.   

Abstract

This study derived a simple equation of effective dose (E) versus normal organ of patients with varying body weights undergoing lung cancer treatment of helical tomotherapy (TOMO). Five tissue-equivalent and Rando phantoms were used to simulate lung cancer patients. This study then measured E and equivalent dose of organ or tissues (DT) using thermoluminescent dosimetry (TLD-100H). The TLD-100H was calibrated using TOMO 6MV photons, then inserted into phantom positions that closely corresponded with the position of the represented organs and tissues. Both E and DT were evaluated by ICRP 103. Peripheral doses varied markedly at positions close to the tumor center. The maximum statistical and total errors were 16.7-22.3%. This analytical result indicates that E of Rando and tissue-equivalent phantoms was in the ranged of 9.44±1.70 (10kg) to 4.58±0.83 (90kg)mSv/Gy. Notably, E decreased exponentially as phantom weight increased. Peripheral doses were also evaluated by TLD as a function of distance from the tumor center. Finally, experimental results are compared with those in literature. These findings will prove useful to patients, physicians, radiologists, and the public.
Copyright © 2015 Elsevier Ltd. All rights reserved.

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Keywords:  Effective dose (E); Equivalent dose of organ or tissues (D(T)); Helical tomotherapy (TOMO); ICRP 103; Lung cancer; Peripheral dose; TLD; Tissue-equivalent phantom

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Year:  2015        PMID: 25935507     DOI: 10.1016/j.apradiso.2015.04.007

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  3 in total

1.  TLD environmental monitoring of new scanner facilities at the Nuclear Medicine Department of the Taiwan Medical University Hospital.

Authors:  Yingyi Le; Jui-Hung Weng; Tsung-Min Lee; Yueh-Chun Lee; Pan-Fu Kao; Lung-Kwang Pan; Chien-Yi Chen
Journal:  Technol Health Care       Date:  2020       Impact factor: 1.285

2.  Radiation doses with various body weights of phantoms in brain 128-slice MDCT examination.

Authors:  Hung-Chih Lin; Te-Jen Lai; Hsien-Chun Tseng; Ching-Hsiang Wang; Yen-Ling Tseng; Chien-Yi Chen
Journal:  J Radiat Res       Date:  2019-07-01       Impact factor: 2.724

3.  Evaluating dose distributions of normal organs for patients undergoing VMAT therapy of nasopharyngeal carcinoma using Rando phantom and TLD-100H.

Authors:  Yun-Chih Chen; Hung-Chih Lin; Wei-Hou Lai; Hung-Chang Hung; Hsien-Chun Tseng; Chien-Yi Chen
Journal:  Technol Health Care       Date:  2022       Impact factor: 1.205

  3 in total

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