| Literature DB >> 25935507 |
Hsien-Chun Tseng1, Wen-Shan Liu2, Hsiao-Han Tsai3, Hsin-Yi Chu4, Jye-Bin Lin5, Chien-Yi Chen6.
Abstract
This study derived a simple equation of effective dose (E) versus normal organ of patients with varying body weights undergoing lung cancer treatment of helical tomotherapy (TOMO). Five tissue-equivalent and Rando phantoms were used to simulate lung cancer patients. This study then measured E and equivalent dose of organ or tissues (DT) using thermoluminescent dosimetry (TLD-100H). The TLD-100H was calibrated using TOMO 6MV photons, then inserted into phantom positions that closely corresponded with the position of the represented organs and tissues. Both E and DT were evaluated by ICRP 103. Peripheral doses varied markedly at positions close to the tumor center. The maximum statistical and total errors were 16.7-22.3%. This analytical result indicates that E of Rando and tissue-equivalent phantoms was in the ranged of 9.44±1.70 (10kg) to 4.58±0.83 (90kg)mSv/Gy. Notably, E decreased exponentially as phantom weight increased. Peripheral doses were also evaluated by TLD as a function of distance from the tumor center. Finally, experimental results are compared with those in literature. These findings will prove useful to patients, physicians, radiologists, and the public.Entities:
Keywords: Effective dose (E); Equivalent dose of organ or tissues (D(T)); Helical tomotherapy (TOMO); ICRP 103; Lung cancer; Peripheral dose; TLD; Tissue-equivalent phantom
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Year: 2015 PMID: 25935507 DOI: 10.1016/j.apradiso.2015.04.007
Source DB: PubMed Journal: Appl Radiat Isot ISSN: 0969-8043 Impact factor: 1.513