Literature DB >> 25934356

The history of Distilbène® (Diethylstilbestrol) told to grandchildren--the transgenerational effect.

Patrick Fénichel1, Françoise Brucker-Davis2, Nicolas Chevalier2.   

Abstract

The Distilbène® story is a dramatic episode which belongs to the history of medicine. It provided several useful lessons such as the importance of evidence-based medicine and the hazard to develop treatments during pregnancy without careful animal verifications. However, this experience has also provided unexpected progress by suggesting new pathophysiological concepts: fetal programming of adult diseases and/or transgenerational transmission of environmental effects through epigenetic modifications.
Copyright © 2015. Published by Elsevier Masson SAS.

Entities:  

Keywords:  Adénocarcinome vaginal; Distilbène(®); Effet transgénérationnel; Endocrine disruptors; Exposition fœtale; Fetal exposure; Hypospadias; Perturbateurs endocriniens; Transgenerational effect; Vaginal adenocarcinoma

Mesh：

Substances：

Year:  2015        PMID： 25934356     DOI： 10.1016/j.ando.2015.03.008

Source DB:  PubMed          Journal:  Ann Endocrinol (Paris)        ISSN： 0003-4266            Impact factor:   2.478


  9 in total

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Journal:  Toxicol Res       Date:  2021-01-25

Review 2.  Are BPA Substitutes as Obesogenic as BPA?

Authors:  Fabiana Oliviero; Alice Marmugi; Catherine Viguié; Véronique Gayrard; Nicole Picard-Hagen; Laila Mselli-Lakhal
Journal:  Int J Mol Sci       Date:  2022-04-11       Impact factor: 6.208

Review 3.  Obesogenic Endocrine Disrupting Chemicals: Identifying Knowledge Gaps.

Authors:  Almudena Veiga-Lopez; Yong Pu; Jeremy Gingrich; Vasantha Padmanabhan
Journal:  Trends Endocrinol Metab       Date:  2018-07-13       Impact factor: 12.015

4.  Determinants of Risk Perception Related to Exposure to Endocrine Disruptors during Pregnancy: A Qualitative and Quantitative Study on French Women.

Authors:  Steeve Rouillon; Houria El Ouazzani; Sylvie Rabouan; Virginie Migeot; Marion Albouy-Llaty
Journal:  Int J Environ Res Public Health       Date:  2018-10-11       Impact factor: 3.390

Review 5.  GPER and Testicular Germ Cell Cancer.

Authors:  Nicolas Chevalier; Charlotte Hinault; Stephan Clavel; Rachel Paul-Bellon; Patrick Fenichel
Journal:  Front Endocrinol (Lausanne)       Date:  2021-01-26       Impact factor: 5.555

Review 6.  On Placental Toxicology Studies and Cerium Dioxide Nanoparticles.

Authors:  Gaëlle Deval; Sonja Boland; Thierry Fournier; Ioana Ferecatu
Journal:  Int J Mol Sci       Date:  2021-11-12       Impact factor: 5.923

7.  Impact of perinatal environmental health education intervention on exposure to endocrine disruptors during pregnancy-PREVED study: study protocol for a randomized controlled trial.

Authors:  Houria El Ouazzani; Steeve Rouillon; Nicolas Venisse; Lynda Sifer-Rivière; Antoine Dupuis; Guillaume Cambien; Sarah Ayraud-Thevenot; Anne-Sophie Gourgues; Pascale Pierre-Eugène; Fabrice Pierre; Sylvie Rabouan; Virginie Migeot; Marion Albouy-Llaty
Journal:  Trials       Date:  2021-12-04       Impact factor: 2.279

8.  Hapten Synthesis and the Development of an Ultrasensitive Indirect Competitive ELISA for the Determination of Diethylstilbestrol in Food Samples.

Authors:  Xingdong Yang; Yinbiao Wang; Chunmei Song; Xiaofei Hu; Fangyu Wang; Xianyin Zeng
Journal:  Sci Rep       Date:  2020-02-24       Impact factor: 4.379

Review 9.  The Adipose Tissue at the Crosstalk Between EDCs and Cancer Development.

Authors:  Emma Bokobza; Charlotte Hinault; Victor Tiroille; Stéphan Clavel; Frédéric Bost; Nicolas Chevalier
Journal:  Front Endocrinol (Lausanne)       Date:  2021-07-20       Impact factor: 5.555
  9 in total

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