Literature DB >> 25932977

Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors.

Yuval Elani1, Robert V Law, Oscar Ces.   

Abstract

Whereas spatial organisation of function is ubiquitous in biology, it has been lacking in artificial cells. We rectify this by using multi-compartment vesicles as chassis for artificial cells, allowing distinct biological processes to be isolated in space. This is demonstrated by in vitro synthesis of two proteins in predefined vesicle regions.

Mesh：

Substances：

Year:  2015        PMID： 25932977     DOI： 10.1039/c4cp05933f

Source DB:  PubMed          Journal:  Phys Chem Chem Phys        ISSN： 1463-9076            Impact factor:   3.676


  26 in total

1.  Multivesicular droplets: a cell model system to study compartmentalised biochemical reactions.

Authors:  N Nuti; P E Verboket; P S Dittrich
Journal:  Lab Chip       Date:  2017-09-12       Impact factor: 6.799

2.  Implanted synthetic cells trigger tissue angiogenesis through de novo production of recombinant growth factors.

Authors:  Gal Chen; Rotem Levin; Shira Landau; Maya Kaduri; Omer Adir; Iris Ianovici; Nitzan Krinsky; Ofri Doppelt-Flikshtain; Jeny Shklover; Janna Shainsky-Roitman; Shulamit Levenberg; Avi Schroeder
Journal:  Proc Natl Acad Sci U S A       Date:  2022-09-12       Impact factor: 12.779

3.  Dynamic Reconfiguration of Subcompartment Architectures in Artificial Cells.

Authors:  Greta Zubaite; James W Hindley; Oscar Ces; Yuval Elani
Journal:  ACS Nano       Date:  2022-06-13       Impact factor: 18.027

4.  A microfluidic platform for size-dependent generation of droplet interface bilayer networks on rails.

Authors:  P Carreras; Y Elani; R V Law; N J Brooks; J M Seddon; O Ces
Journal:  Biomicrofluidics       Date:  2015-12-30       Impact factor: 2.800

5.  A MATLAB toolbox for modeling genetic circuits in cell-free systems.

Authors:  Vipul Singhal; Zoltan A Tuza; Zachary Z Sun; Richard M Murray
Journal:  Synth Biol (Oxf)       Date:  2021-02-05

6.  A Detailed Protocol for Preparing Millimeter-sized Supergiant Liposomes that Permit Efficient Eukaryotic Cell-free Translation in the Interior.

Authors:  Hajime Takahashi; Atsushi Ogawa
Journal:  Bio Protoc       Date:  2021-06-20

7.  Synthetic Cells Synthesize Therapeutic Proteins inside Tumors.

Authors:  Nitzan Krinsky; Maya Kaduri; Assaf Zinger; Janna Shainsky-Roitman; Mor Goldfeder; Itai Benhar; Dov Hershkovitz; Avi Schroeder
Journal:  Adv Healthc Mater       Date:  2017-12-28       Impact factor: 11.092

Review 8.  Artificial cell mimics as simplified models for the study of cell biology.

Authors:  Ali Salehi-Reyhani; Oscar Ces; Yuval Elani
Journal:  Exp Biol Med (Maywood)       Date:  2017-06-04

9.  Modelling compartmentalization towards elucidation and engineering of spatial organization in biochemical pathways.

Authors:  Govind Menon; Chinedu Okeke; J Krishnan
Journal:  Sci Rep       Date:  2017-09-21       Impact factor: 4.379

Review 10.  Construction of membrane-bound artificial cells using microfluidics: a new frontier in bottom-up synthetic biology.

Authors:  Yuval Elani
Journal:  Biochem Soc Trans       Date:  2016-06-15       Impact factor: 5.407
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.