| Literature DB >> 25932784 |
Zoya Cheglakov1, Timothy M Cronin2, Chuan He1, Yossi Weizmann2.
Abstract
Recent advances in RNA research have posed new directives in biology and chemistry to uncover the complex roles of ribonucleic acids in cellular processes. Innovative techniques to visualize native RNAs, particularly, short, low-abundance RNAs in live cells, can dramatically impact current research on the roles of RNAs in biology. Herein, we report a novel method for real-time, microRNA imaging inside live cells based on programmable oligonucleotide probes, which self-assemble through the Cascade Hybridization Reaction (CHR).Entities:
Mesh：
Substances：
Year: 2015 PMID： 25932784 DOI： 10.1021/jacs.5b01451
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419