Literature DB >> 25923188

Fatty acid and phospholipase A2 plasma levels in children with autism.

Márcia Helena Fávero de Souza Tostes1, Hudson Caetano Polonini2, Rosemeri Mendes2, Marcos Antônio Fernandes Brandão1, Wagner Farid Gattaz3, Nádia Rezende Barbosa Raposo1.   

Abstract

OBJECTIVE: To evaluate fatty acid plasma levels, phospholipase A2 activity, and the developmental profiles of children with autism vs. control subjects.
METHODS: Twenty four children with autism underwent laboratory analysis for fatty acid quantification using gas chromatography and PLA2 activity determination by fluorometric assay.
RESULTS: No correlation was observed between the developmental quotient and fatty acid plasma levels. Phospholipase A2 activity was significantly higher among autistic children compared with controls.
CONCLUSION: The study did not show a correlation between fatty acid and phospholipase A2 plasma levels and the developmental profile of children with autism.

Entities:  

Year:  2013        PMID： 25923188     DOI： 10.1590/s2237-60892013000100009

Source DB:  PubMed          Journal:  Trends Psychiatry Psychother        ISSN： 2237-6089


  2 in total

Review 1.  Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota.

Authors:  Charlotte Madore; Quentin Leyrolle; Chloé Lacabanne; Anouk Benmamar-Badel; Corinne Joffre; Agnes Nadjar; Sophie Layé
Journal:  Neural Plast       Date:  2016-10-20       Impact factor: 3.599

Review 2.  Relationship between Long Chain n-3 Polyunsaturated Fatty Acids and Autism Spectrum Disorder: Systematic Review and Meta-Analysis of Case-Control and Randomised Controlled Trials.

Authors:  Hajar Mazahery; Welma Stonehouse; Maryam Delshad; Marlena C Kruger; Cathryn A Conlon; Kathryn L Beck; Pamela R von Hurst
Journal:  Nutrients       Date:  2017-02-19       Impact factor: 5.717
  2 in total

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