INTRODUCTION: Almost all studies on diabetic foot syndrome focused on prevention of amputation and did not investigate long-term prognosis and survival of patients as a primary outcome parameter. METHODS: We did a retrospective cohort study including 314 patients who had diabetic foot syndrome and underwent amputation between December 1995 and January 2001. RESULTS: A total of 48% of patients received minor amputation (group I), 15% only major amputation (group II) and 36% initially underwent a minor amputation that was followed by a major amputation (group III). Statistically significant differences were observed in comparison of the median survival of group I to group II (51 vs. 40 months; p = 0.016) and of group II to group III (40 vs. 55 months; p = 0.003). DISCUSSION: The prognosis of patients with major amputation due to diabetic foot syndrome is comparable to patients with malignant diseases. Vascular interventions did not improve the individual prognosis of patients.
INTRODUCTION: Almost all studies on diabetic foot syndrome focused on prevention of amputation and did not investigate long-term prognosis and survival of patients as a primary outcome parameter. METHODS: We did a retrospective cohort study including 314 patients who had diabetic foot syndrome and underwent amputation between December 1995 and January 2001. RESULTS: A total of 48% of patients received minor amputation (group I), 15% only major amputation (group II) and 36% initially underwent a minor amputation that was followed by a major amputation (group III). Statistically significant differences were observed in comparison of the median survival of group I to group II (51 vs. 40 months; p = 0.016) and of group II to group III (40 vs. 55 months; p = 0.003). DISCUSSION: The prognosis of patients with major amputation due to diabetic foot syndrome is comparable to patients with malignant diseases. Vascular interventions did not improve the individual prognosis of patients.
Authors: S Borys; J Hohendorff; T Koblik; P Witek; A H Ludwig-Slomczynska; C Frankfurter; B Kiec-Wilk; M T Malecki Journal: Endocrine Date: 2018-08-11 Impact factor: 3.633
Authors: Silvia Cascini; Nera Agabiti; Marina Davoli; Luigi Uccioli; Marco Meloni; Laura Giurato; Claudia Marino; Anna Maria Bargagli Journal: BMJ Open Diabetes Res Care Date: 2020-07
Authors: S Borys; A H Ludwig-Slomczynska; M Seweryn; J Hohendorff; T Koblik; J Machlowska; B Kiec-Wilk; P Wolkow; Maciej T Malecki Journal: Acta Diabetol Date: 2018-09-17 Impact factor: 4.280