Literature DB >> 2592021

Molecular cloning and chromosomal assignment of a human perforin (PFP) gene.

Y Shinkai1, M C Yoshida, K Maeda, T Kobata, K Maruyama, J Yodoi, H Yagita, K Okumura.   

Abstract

Human perforin cDNA was isolated and the complete nucleotide sequence of the gene determined. The deduced amino acid sequence of human perforin showed 68.4% similarity to that of mouse perforin. RNA blot analysis of the human perforin gene revealed that the gene product is expressed preferentially in killer-type cells among cell lines tested, and in large granular lymphocytes among the peripheral blood mononuclear cells. In situ hybridization analysis with a human perforin cDNA probe revealed that the human perforin (PFP) gene is located on chromosome 17q11-21.

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Year:  1989        PMID： 2592021     DOI： 10.1007/bf02421177

Source DB:  PubMed          Journal:  Immunogenetics        ISSN： 0093-7711            Impact factor:   2.846


  18 in total

1.  The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities.

Authors:  J D Young; Z A Cohn; E R Podack
Journal:  Science       Date:  1986-07-11       Impact factor: 47.728

2.  Regional location of a novel yes-related proto-oncogene, syn, on human chromosome 6 at band q21.

Authors:  M C Yoshida; H Satoh; M Sasaki; K Semba; T Yamamoto; K Toyoshima
Journal:  Jpn J Cancer Res       Date:  1986-11

3.  Homology of perforin to the ninth component of complement (C9).

Authors:  Y Shinkai; K Takio; K Okumura
Journal:  Nature       Date:  1988-08-11       Impact factor: 49.962

4.  Report of the committee on the genetic constitution of chromosome 17.

Authors:  E Solomon; D Barker
Journal:  Cytogenet Cell Genet       Date:  1988

5.  Electron microscopic demonstration of lesions in target cell membranes associated with antibody-dependent cellular cytotoxicity.

Authors:  R R Dourmashkin; P Deteix; C B Simone; P Henkart
Journal:  Clin Exp Immunol       Date:  1980-12       Impact factor: 4.330

6.  Molecular cloning of rat cytolysin.

Authors:  H Ishikawa; Y Shinkai; H Yagita; C C Yue; P A Henkart; S Sawada; H A Young; C W Reynolds; K Okumura
Journal:  J Immunol       Date:  1989-11-01       Impact factor: 5.422

7.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

8.  The C8A and C8B loci are closely linked on chromosome 1.

Authors:  S Rogde; B Olaisen; T Gedde-Dahl; P Teisberg
Journal:  Ann Hum Genet       Date:  1986-05       Impact factor: 1.670

9.  Resistance of cytolytic lymphocytes to perforin-mediated killing. Lack of correlation with complement-associated homologous species restriction.

Authors:  S B Jiang; P M Persechini; A Zychlinsky; C C Liu; B Perussia; J D Young
Journal:  J Exp Med       Date:  1988-12-01       Impact factor: 14.307

10.  Natural killer-mediated lysis of normal and malignant target cells, and its regulation by monocytes.

Authors:  K Oshimi; Y Oshimi; M Satake; H Mizoguchi
Journal:  J Exp Med       Date:  1985-08-01       Impact factor: 14.307
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  15 in total

Review 1.  Perforin and its role in T lymphocyte-mediated cytolysis.

Authors:  B Lowin; O Krähenbühl; C Müller; M Dupuis; J Tschopp
Journal:  Experientia       Date:  1992-10-15

2.  Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain.

Authors:  R Uellner; M J Zvelebil; J Hopkins; J Jones; L K MacDougall; B P Morgan; E Podack; M D Waterfield; G M Griffiths
Journal:  EMBO J       Date:  1997-12-15       Impact factor: 11.598

3.  Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis.

Authors:  K Göransdotter Ericson; B Fadeel; S Nilsson-Ardnor; C Söderhäll; A Samuelsson; G Janka; M Schneider; A Gürgey; N Yalman; T Révész; R Egeler; K Jahnukainen; I Storm-Mathiesen; A Haraldsson ; J Poole; G de Saint Basile; M Nordenskjöld; J Henter
Journal:  Am J Hum Genet       Date:  2001-02-06       Impact factor: 11.025

4.  Activation of human monocytes induces differential resistance to apoptosis with rapid down regulation of caspase-8/FLICE.

Authors:  L P Perera; T A Waldmann
Journal:  Proc Natl Acad Sci U S A       Date:  1998-11-24       Impact factor: 11.205

5.  Perforin mRNA expression in the inflamed tissues of NZB/W F1 lupus mice decreases with methylprednisolone treatment.

Authors:  T Nakamura; I Ebihara; Y Tomino; K Okumura; H Koide
Journal:  Am J Pathol       Date:  1991-10       Impact factor: 4.307

6.  The human complement component C8B gene: structure and phylogenetic relationship.

Authors:  T Kaufmann; C Rittner; P M Schneider
Journal:  Hum Genet       Date:  1993-08       Impact factor: 4.132

7.  Cytokine mRNA profiles in mononuclear cells in acute aseptic meningoencephalitis.

Authors:  V Navikas; M Haglund; J Link; B He; L Lindqvist; S Fredrikson; H Link
Journal:  Infect Immun       Date:  1995-04       Impact factor: 3.441

8.  Establishment and functional characterization of human herpesvirus 6-specific CD4+ human T-cell clones.

Authors:  Y Yakushijin; M Yasukawa; Y Kobayashi
Journal:  J Virol       Date:  1992-05       Impact factor: 5.103

9.  Different localization of lysosomal-associated membrane protein 1 (LAMP1) in mammalian cultured cell lines.

Authors:  Kosuke Baba; Sara Kuwada; Ayaka Nakao; Xuebing Li; Naoaki Okuda; Ai Nishida; Satoshi Mitsuda; Natsuki Fukuoka; Hideaki Kakeya; Takao Kataoka
Journal:  Histochem Cell Biol       Date:  2020-01-06       Impact factor: 4.304

10.  Perforin-secreting killer cell infiltration and expression of a 65-kD heat-shock protein in aortic tissue of patients with Takayasu's arteritis.

Authors:  Y Seko; S Minota; A Kawasaki; Y Shinkai; K Maeda; H Yagita; K Okumura; O Sato; A Takagi; Y Tada
Journal:  J Clin Invest       Date:  1994-02       Impact factor: 14.808
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