Literature DB >> 25918864

An ultra-low cost NMR device with arbitrary pulse programming.

Hsueh-Ying Chen1, Yaewon Kim1, Pulak Nath2, Christian Hilty3.   

Abstract

Ultra-low cost, general purpose electronics boards featuring microprocessors or field programmable gate arrays (FPGA) are reaching capabilities sufficient for direct implementation of NMR spectrometers. We demonstrate a spectrometer based on such a board, implemented with a minimal need for the addition of custom electronics and external components. This feature allows such a spectrometer to be readily implemented using typical knowledge present in an NMR laboratory. With FPGA technology, digital tasks are performed with precise timing, without the limitation of predetermined hardware function. In this case, the FPGA is used for programming of arbitrarily timed pulse sequence events, and to digitally generate required frequencies. Data acquired from a 0.53T permanent magnet serves as a demonstration of the flexibility of pulse programming for diverse experiments. Pulse sequences applied include a spin-lattice relaxation measurement using a pulse train with small-flip angle pulses, and a Carr-Purcell-Meiboom-Gill experiment with phase cycle. Mixing of NMR signals with a digitally generated, 4-step phase-cycled reference frequency is further implemented to achieve sequential quadrature detection. The flexibility in hardware implementation permits tailoring this type of spectrometer for applications such as relaxometry, polarimetry, diffusometry or NMR based magnetometry.
Copyright © 2015 Elsevier Inc. All rights reserved.

Keywords:  NMR hardware; Portable NMR; Relaxometry

Year:  2015        PMID: 25918864     DOI: 10.1016/j.jmr.2015.02.011

Source DB:  PubMed          Journal:  J Magn Reson        ISSN: 1090-7807            Impact factor:   2.229


  4 in total

1.  The MR Cap: A single-sided MRI system designed for potential point-of-care limited field-of-view brain imaging.

Authors:  Patrick C McDaniel; Clarissa Zimmerman Cooley; Jason P Stockmann; Lawrence L Wald
Journal:  Magn Reson Med       Date:  2019-06-23       Impact factor: 4.668

2.  Reimagining magnetic resonance instrumentation using open maker tools and hardware as protocol.

Authors:  Jessica I Kelz; Jose L Uribe; Rachel W Martin
Journal:  J Magn Reson Open       Date:  2021-01-30

3.  An open-source, low-cost NMR spectrometer operating in the mT field regime.

Authors:  Nicholas Bryden; Michael Antonacci; Michele Kelley; Rosa T Branca
Journal:  J Magn Reson       Date:  2021-09-27       Impact factor: 2.734

Review 4.  EPR Everywhere.

Authors:  Joshua R Biller; Joseph E McPeak
Journal:  Appl Magn Reson       Date:  2021-01-24       Impact factor: 0.831

  4 in total

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