Literature DB >> 25916025

The colorectal cancer screening program in the local health unit n. 6 of Livorno: evaluation of the screening activity in the period 2000-2011.

A Zani, S De Masi, C Maffei, S Malloggi, M Benvenuti, V Gioli, G Niccoli, K P Biermann, P Lopane.   

Abstract

INTRODUCTION: The colorectal cancer screening program in the Local Health Unit n. 6 of Livorno is running since July 2000 and is meant to residents, aged between 50 and 70, who are invited to perform the test for faecal occult blood every 2 years. The aim of this work is an evaluation of the screening activity in the period 2000-2011.
METHODS: The evaluation is based on the analysis of the main quality indicators formulated by GISCoR (Italian Group for Colorectal screening).
RESULTS: The screening activity extension reached 93% in 2006 and 100% in 2009. The compliance level was maintained above the acceptable GISCoR value (> 45%) with a maximum of 54.9%. Values around 80% were recorded for the compliance to colonoscopy. The detection rate (DR) for cancer and advanced adenoma showed, as expected, the highest values in the early years and then move on values consistently lower than the regional average. In 2011, the raw DR for cancer was 0.9 x 1000 and the raw DR for advanced adenoma 5.3 x 1000. The distribution by stage at diagnosis of screen-detected carcinomas shows that 58.1% of these were identified at stage I while the proportion of cases in stage III+ is 19.5%.
CONCLUSIONS: The overall analysis shows a good performance of the program. The proportion of colonoscopies performed on the total number of positive subjects remains a critical point of the system. The distribution by stage of screen-detected cancers shows an excellent diagnostic anticipation of the screening program.

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Year:  2014        PMID: 25916025      PMCID: PMC4718338     

Source DB:  PubMed          Journal:  J Prev Med Hyg        ISSN: 1121-2233


  7 in total

1.  The effect of fecal occult-blood screening on the incidence of colorectal cancer.

Authors:  J S Mandel; T R Church; J H Bond; F Ederer; M S Geisser; S J Mongin; D C Snover; L M Schuman
Journal:  N Engl J Med       Date:  2000-11-30       Impact factor: 91.245

2.  Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial.

Authors:  Wendy S Atkin; Rob Edwards; Ines Kralj-Hans; Kate Wooldrage; Andrew R Hart; John M A Northover; D Max Parkin; Jane Wardle; Stephen W Duffy; Jack Cuzick
Journal:  Lancet       Date:  2010-04-27       Impact factor: 79.321

Review 3.  Screening for colorectal cancer using the faecal occult blood test, hemoccult.

Authors:  B P Towler; L Irwig; P Glasziou; D Weller; J Kewenter
Journal:  Cochrane Database Syst Rev       Date:  2000

4.  Colorectal cancer mortality: effectiveness of biennial screening for fecal occult blood.

Authors:  J S Mandel; T R Church; F Ederer; J H Bond
Journal:  J Natl Cancer Inst       Date:  1999-03-03       Impact factor: 13.506

5.  Randomised controlled trial of faecal-occult-blood screening for colorectal cancer.

Authors:  J D Hardcastle; J O Chamberlain; M H Robinson; S M Moss; S S Amar; T W Balfour; P D James; C M Mangham
Journal:  Lancet       Date:  1996-11-30       Impact factor: 79.321

6.  Randomised study of screening for colorectal cancer with faecal-occult-blood test.

Authors:  O Kronborg; C Fenger; J Olsen; O D Jørgensen; O Søndergaard
Journal:  Lancet       Date:  1996-11-30       Impact factor: 79.321

7.  [Ouality indicators for the evaluation of colorectal cancer screening programmes].

Authors:  Manuel Zorzi; Priscilla Sassoli de' Bianchi; Grazia Grazzini; Carlo Senore
Journal:  Epidemiol Prev       Date:  2007 Nov-Dec       Impact factor: 1.901

  7 in total

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