| Literature DB >> 25914022 |
Paul Bg van Erp1, Gary Bloomer2, Royce Wilkinson1, Blake Wiedenheft3.
Abstract
The interface between viruses and their hosts' are hot spots for biological and biotechnological innovation. Bacteria use restriction endonucleases to destroy invading DNA, and industry has exploited these enzymes for molecular cut-and-paste reactions that are central to many recombinant DNA technologies. Today, another class of nucleases central to adaptive immune systems that protect bacteria and archaea from invading viruses and plasmids are blazing a similar path from basic science to profound biomedical and industrial applications.Entities:
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Year: 2015 PMID： 25914022 PMCID： PMC4470805 DOI： 10.1016/j.coviro.2015.03.011
Source DB: PubMed Journal: Curr Opin Virol ISSN： 1879-6257 Impact factor: 7.090