Literature DB >> 25909027

Temporal and spatial temperature distributions on glabrous skin irradiated by a 1940 nm continuous-wave laser stimulator.

Ji-Chun Yang1, Xiao-Xi Dong2, Zhi-Ming Mu1, Wen-Dong Jin1, He Huang1, Yu Lu3, Zhu-Ying Chen1, Ying-Xin Li1.   

Abstract

For predicting pain stimulation effects and avoiding damage in 1940nm laser evoked potentials (LEPs) experiments, a 2-layer finite element model (FEM-2) was constructed. A series of experiments were conducted on ex-vivo pig skin pieces to verify temperature distribution predicted by this model. Various laser powers and beam radii were employed. Experimental data of time-dependent temperature responses in different sub-skin depths and space-dependent surface temperature was recorded by thermocouple instrument. By comparing with the experimental data and model results, FEM-2 model was proved to predict temperature distributions accurately. A logarithmic relationship between laser power density and temperature increment was revealed by the results. It is concluded that power density is an effective parameter to estimate pain and damage effect. The obtained results also indicated that the proposed FEM-2 model can be extended to predict pain and damage thresholds of human skin samples and thus contribute to LEPs study.

Entities:  

Keywords:  (140.0140) Lasers and laser optics; (140.3330) Laser damage; (140.3580) Lasers, solid-state; (140.6810) Thermal effects; (170.0170) Medical optics and biotechnology; (170.3660) Light propagation in tissues

Year:  2015        PMID: 25909027      PMCID: PMC4399682          DOI: 10.1364/BOE.6.001451

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN: 2156-7085            Impact factor:   3.732


  19 in total

Review 1.  The vanilloid receptor: a molecular gateway to the pain pathway.

Authors:  M J Caterina; D Julius
Journal:  Annu Rev Neurosci       Date:  2001       Impact factor: 12.449

Review 2.  Molecular mechanisms of nociception.

Authors:  D Julius; A I Basbaum
Journal:  Nature       Date:  2001-09-13       Impact factor: 49.962

Review 3.  How do we selectively activate skin nociceptors with a high power infrared laser? Physiology and biophysics of laser stimulation.

Authors:  L Plaghki; A Mouraux
Journal:  Neurophysiol Clin       Date:  2003-12       Impact factor: 3.734

4.  Refractive indices of water and ice in the 0.65- to 2.5-µm spectral range.

Authors:  L Kou; D Labrie; P Chylek
Journal:  Appl Opt       Date:  1993-07-01       Impact factor: 1.980

5.  A novel modelling and experimental technique to predict and measure tissue temperature during CO2 laser stimuli for human pain studies.

Authors:  Mohammed Hamed Al-Saadi; V Nadeau; M R Dickinson
Journal:  Lasers Med Sci       Date:  2006-05-04       Impact factor: 3.161

6.  Laser emitted radiant heat for pain research.

Authors:  Joseph Mor; Amiram Carmon
Journal:  Pain       Date:  1975-09       Impact factor: 6.961

7.  Finite element analysis of thermal laser skin stimulation for a finer characterization of the nociceptive system.

Authors:  E Marchandise; A Mouraux; L Plaghki; F Henrotte
Journal:  J Neurosci Methods       Date:  2013-12-03       Impact factor: 2.390

8.  Modeling optical and thermal distributions in tissue during laser irradiation.

Authors:  S L Jacques; S A Prahl
Journal:  Lasers Surg Med       Date:  1987       Impact factor: 4.025

9.  Spatial temperature distribution in human hairy and glabrous skin after infrared CO2 laser radiation.

Authors:  Ken S Frahm; Ole K Andersen; Lars Arendt-Nielsen; Carsten D Mørch
Journal:  Biomed Eng Online       Date:  2010-11-08       Impact factor: 2.819

Review 10.  Lasers and other thermal stimulators for activation of skin nociceptors in humans.

Authors:  L Arendt-Nielsen; A C N Chen
Journal:  Neurophysiol Clin       Date:  2003-12       Impact factor: 3.734

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  1 in total

1.  A novel dual-wavelength laser stimulator to elicit transient and tonic nociceptive stimulation.

Authors:  Xiaoxi Dong; Tianjun Liu; Han Wang; Jichun Yang; Zhuying Chen; Yong Hu; Yingxin Li
Journal:  Lasers Med Sci       Date:  2017-05-20       Impact factor: 3.161

  1 in total

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