Literature DB >> 25908998

Q-r curve of thermal tomography and its clinical application on breast tumor diagnosis.

Guilian Shi1, Fei Han2, Lin Wang2, Chengwen Liang2, Kaiyang Li2.   

Abstract

Heat is the product following the metabolism of cells, and the metabolism is closely related with the pathological information of living organism. So, there are strong ties between the heat distribution and the pathological state in living organism. In this paper, the mathematical function δ is introduced in the classical Pennes bio-heat transfer equation as the point heat source. By simplifying the boundary conditions, a novel bio-heat transfer model is established and solved in a spherical coordinate system. Based on the temperature distribution of human body surface, the information of heat source is mined layer by layer, and the corresponding q-r curve of heat intensity varying with depth is acquired combining the fitting method of Lorentz curve. According to a large number of clinical confirmed cases and statistics, the diagnostic criteria judging diseases by q-r curve are proposed. Five typical clinical practices are performed and four of the diagnosis results are very consistent with those of molybdenum target (MT) X-ray, B-ultrasonic images and pathological examination, one gives the result of early stage malignant tumor that MT X-ray and B-ultrasonic can't check out. It is a radiation-free green method with noninvasive diagnostic procedure and accurate diagnosis result.

Entities:  

Keywords:  (170.3660) Light propagation in tissues; (170.4580) Optical diagnostics for medicine; (170.6510) Spectroscopy, tissue diagnostics

Year:  2015        PMID: 25908998      PMCID: PMC4399653          DOI: 10.1364/BOE.6.001109

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN: 2156-7085            Impact factor:   3.732


  16 in total

Review 1.  Functional infrared imaging of the breast.

Authors:  J R Keyserlingk; P D Ahlgren; E Yu; N Belliveau; M Yassa
Journal:  IEEE Eng Med Biol Mag       Date:  2000 May-Jun

2.  Model-based assessment of tissue perfusion and temperature in deep hypothermic patients.

Authors:  Michael Schwarz; Martin W Krueger; Hans-Jörg Busch; Christoph Benk; Claudia Heilmann
Journal:  IEEE Trans Biomed Eng       Date:  2010-05-03       Impact factor: 4.538

3.  A Novel Approach of Analyzing the Relation between the Inner Heat Source and the Surface Temperature Distribution in Thermal Texture Maps.

Authors:  Gao Chunfang; Li Kaiyang; Zhang Shaoping
Journal:  Conf Proc IEEE Eng Med Biol Soc       Date:  2005

4.  Numerical analysis for determination of the presence of a tumor and estimation of its size and location in a tissue.

Authors:  Koushik Das; Rupesh Singh; Subhash C Mishra
Journal:  J Therm Biol       Date:  2012-10-26       Impact factor: 2.902

5.  Band analysis of hydrated human skin stratum corneum attenuated total reflectance fourier transform infrared spectra in vivo.

Authors:  G W Lucassen; G N van Veen; J A Jansen
Journal:  J Biomed Opt       Date:  1998-07       Impact factor: 3.170

6.  Procedure to estimate thermophysical and geometrical parameters of embedded cancerous lesions using thermography.

Authors:  Jose Manuel Luna; Ricardo Romero-Mendez; Abel Hernandez-Guerrero; Francisco Elizalde-Blancas
Journal:  J Biomech Eng       Date:  2012-03       Impact factor: 2.097

7.  Thermography based breast cancer detection using texture features and Support Vector Machine.

Authors:  U Rajendra Acharya; E Y K Ng; Jen-Hong Tan; S Vinitha Sree
Journal:  J Med Syst       Date:  2010-10-19       Impact factor: 4.460

8.  A multimodal platform for nonlinear optical microscopy and microspectroscopy.

Authors:  Hongtao Chen; Haifeng Wang; Mikhail N Slipchenko; YooKyung Jung; Yunzhou Shi; Jiabin Zhu; Kimberly K Buhman; Ji-Xin Cheng
Journal:  Opt Express       Date:  2009-02-02       Impact factor: 3.894

9.  Boundary element method with bioheat equation for skin burn injury.

Authors:  E Y K Ng; H M Tan; E H Ooi
Journal:  Burns       Date:  2009-05-07       Impact factor: 2.744

10.  Study of the one dimensional and transient bioheat transfer equation: multi-layer solution development and applications.

Authors:  D B Rodrigues; P J S Pereira; P Limão-Vieira; P R Stauffer; P F Maccarini
Journal:  Int J Heat Mass Transf       Date:  2013-07-01       Impact factor: 5.584

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  4 in total

1.  Detection theory for accurate and non-invasive skin cancer diagnosis using dynamic thermal imaging.

Authors:  Sebastián E Godoy; Majeed M Hayat; David A Ramirez; Stephen A Myers; R Steven Padilla; Sanjay Krishna
Journal:  Biomed Opt Express       Date:  2017-03-22       Impact factor: 3.732

2.  Identification of UCP1 and UCP2 as Potential Prognostic Markers in Breast Cancer: A Study Based on Immunohistochemical Analysis and Bioinformatics.

Authors:  Xin Yu; Manman Shi; Qi Wu; Wen Wei; Shengrong Sun; Shan Zhu
Journal:  Front Cell Dev Biol       Date:  2022-07-07

3.  Thermal tomography for monitoring tumor response to neoadjuvant chemotherapy in women with locally advanced breast cancer.

Authors:  Qi Wu; Juanjuan Li; Si Sun; Xiaoli Yao; Shan Zhu; Juan Wu; Qian Liu; Xiaojun Ding; Manman Shi; Kaiyang Li; Shengrong Sun
Journal:  Oncotarget       Date:  2017-03-25

4.  Risk of breast cancer based on thermal tomography characteristics.

Authors:  Si Sun; Xin Yu; Juanjuan Li; Zhiyu Li; Shan Zhu; Lijun Wang; Juan Wu; Kaiyang Li; Qi Wu; Shengrong Sun
Journal:  Transl Cancer Res       Date:  2019-08       Impact factor: 1.241

  4 in total

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