Literature DB >> 2590601

The effect of phentolamine on basal and pethidine-induced inhibition of gastric emptying in healthy volunteers.

O U Petring1.   

Abstract

1. The effect of phentolamine 5 mg i.v. on basal and pethidine-induced inhibition of gastric emptying of semisolid TC-99m labelled Chelex-100 resin/oatmeal was studied in ten healthy volunteers. 2. Each volunteer acted as his/her own control. 3. Basal gastric emptying remained unchanged after administration of phentolamine. 4. Administration of phentolamine reversed the pethidine-induced inhibition of gastric emptying.

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Year:  1989        PMID： 2590601      PMCID： PMC1379990          DOI： 10.1111/j.1365-2125.1989.tb03520.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  16 in total

1.  Comparison of the effect of cisapride and metoclopramide on morphine-induced delay in gastric emptying.

Authors:  D J Rowbotham; P A Bamber; W S Nimmo
Journal:  Br J Clin Pharmacol       Date:  1988-12       Impact factor: 4.335

2.  The relationship between gastric emptying of semisolids and paracetamol absorption.

Authors:  O U Petring; B Adelhøj; M Ibsen; H E Poulsen
Journal:  Br J Clin Pharmacol       Date:  1986-12       Impact factor: 4.335

Review 3.  Central control of human gastrointestinal function.

Authors:  D G Thompson
Journal:  Baillieres Clin Gastroenterol       Date:  1988-01

4.  Effect of opiate and adrenergic blockers on the gut motor response to centrally acting stimuli.

Authors:  V Stanghellini; J R Malagelada; A R Zinsmeister; V L Go; P C Kao
Journal:  Gastroenterology       Date:  1984-11       Impact factor: 22.682

5.  The action of dazopride to enhance gastric emptying and block emesis.

Authors:  B Costall; A M Domeney; S J Gunning; M E Kelly; R J Naylor; V Nohria; J B Owera-Atepo; K M Simpson; C C Tan; D Tattersall
Journal:  Neuropharmacology       Date:  1987-07       Impact factor: 5.250

Review 6.  Studies on the role of dopamine and dopamine blockers in gastroduodenal motility.

Authors:  J M Van Nueten; J A Schuurkes
Journal:  Scand J Gastroenterol Suppl       Date:  1984

7.  Role of dopamine and alpha-adrenoreceptors in the control of gastric emptying in the rat: possible involvement in the mechanism of action of metoclopramide.

Authors:  S M Cooper; B McRitchie
Journal:  J Auton Pharmacol       Date:  1985-12

8.  Analgesic and gastrointestinal effects of nalbuphine--a comparison with pethidine.

Authors:  P J Slattery; A Mark; R A Couch
Journal:  Anaesth Intensive Care       Date:  1986-05       Impact factor: 1.669

9.  The action of cisapride on gastric emptying and the pharmacodynamics and pharmacokinetics of oral diazepam.

Authors:  D N Bateman
Journal:  Eur J Clin Pharmacol       Date:  1986       Impact factor: 2.953

Review 10.  Action of opiates on gastrointestinal function.

Authors:  L Bueno; J Fioramonti
Journal:  Baillieres Clin Gastroenterol       Date:  1988-01
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  2 in total

1.  Inter- and intrasubject variability of gastric emptying in healthy volunteers measured by scintigraphy and paracetamol absorption.

Authors:  O U Petring; H Flachs
Journal:  Br J Clin Pharmacol       Date:  1990-06       Impact factor: 4.335

Review 2.  Pharmacokinetic considerations in gastrointestinal motor disorders.

Authors:  G S Hebbard; W M Sun; F Bochner; M Horowitz
Journal:  Clin Pharmacokinet       Date:  1995-01       Impact factor: 6.447
  2 in total

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