An Tang1,2,3, Guy Cloutier2,3,4,5, Nikolaus M Szeverenyi6, Claude B Sirlin6. 1. 1 Department of Radiology, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, QC, Canada. 2. 2 Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada. 3. 3 Department of Radiology, Radio-Oncology and Nuclear Medicine, Université de Montréal, Pavillon Roger-Gaudry, Local S-716, Montréal, QC, Canada. 4. 4 Institute of Biomedical Engineering, Université de Montréal, Montréal, QC, Canada. 5. 5 Laboratory of Biorheology and Medical Ultrasonics, CRCHUM, Montréal, QC, Canada. 6. 6 Liver Imaging Group, Department of Radiology, University of California San Diego, 408 Dickinson St, San Diego, CA 92103-8226.
Abstract
OBJECTIVE: The purpose of the article is to review the diagnostic performance of ultra-sound and MR elastography techniques for detection and staging of liver fibrosis, the main current clinical applications of elastography in the abdomen. CONCLUSION: Technical and instrument-related factors and biologic and patient-related factors may constitute potential confounders of stiffness measurements for assessment of liver fibrosis. Future developments may expand the scope of elastography for monitoring liver fibrosis and predict complications of chronic liver disease.
OBJECTIVE: The purpose of the article is to review the diagnostic performance of ultra-sound and MR elastography techniques for detection and staging of liver fibrosis, the main current clinical applications of elastography in the abdomen. CONCLUSION: Technical and instrument-related factors and biologic and patient-related factors may constitute potential confounders of stiffness measurements for assessment of liver fibrosis. Future developments may expand the scope of elastography for monitoring liver fibrosis and predict complications of chronic liver disease.
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